Development of a homogeneous screening assay for automated detection of antiviral agents active against severe acute respiratory syndrome-associated coronavirusArticle Published on 2005-06-142022-11-01 Journal: Journal of virological methods [Category] Coronavirus, [키워드] 2003 active against Antiviral antiviral activity antiviral agent Antiviral compounds antiviral drug antiviral potency assay automated be applied compounds coronavirus cytotoxicity demonstrated detect development Drug discovery EGFP expression evaluated Express facilitate fluorescent gastroenteritis Health High-throughput screening homogeneous inhibitor initial screening outbreak Protein risk SARS-CoV SARS-CoV infection severity specificity Spread therapeutic agent viral disease virus viruses [DOI] 10.1016/j.jviromet.2005.05.010 PMC 바로가기 [Article Type] Article
Longitudinally Profiling Neutralizing Antibody Response to SARS Coronavirus with PseudotypesResearch Published on 2005-03-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] 2003 229E against SARS-CoV antibody coronavirus coronavirus strain correlated cross-neutralization determine develop emerging handling Hong Kong human sera Immunity in vitro Infectious diseases long-lasting microneutralization natural infection neutralization tests Neutralizing antibodies Neutralizing antibody response Neutralizing titer NO OC43 occurred outbreak Profiling pseudotype recovered patients Research response SARS patient SARS virus SARS-CoV SARS-CoV neutralizing antibodies SARS-CoV S SARS-CoV spike protein serum sample Spike protein Vaccines was used [DOI] 10.3201/eid1103.040906 PMC 바로가기 [Article Type] Research
SARS Transmission Pattern in Singapore Reassessed by Viral Sequence Variation AnalysisResearch Article Published on 2005-02-222022-10-29 Journal: PLoS Medicine [Category] Coronavirus, [키워드] accurate acquisition acute respiratory syndrome Analysis approach clinical sample clinical samples Contact demonstrated dependent on detect different Direct effective Epidemiological investigation epidemiological link Epidemiological study finding genetic analysis Genetic variation heterogeneous Host Infectious disease information isolate isolates lung tissues mass molecular nine outbreak overcome pathogen pathogen transmission Patient pattern population level problems provide quasispecy SARS Coronavirus SARS-CoV Sequence analysis sequence variation Singapore Stage thought variety Viral RNA viral sequence virus was determined [DOI] 10.1371/journal.pmed.0020043 PMC 바로가기 [Article Type] Research Article
Wild Animal Mortality Monitoring and Human Ebola Outbreaks, Gabon and Republic of Congo, 2001–2003Article Published on 2005-02-012023-05-31 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] Congo Duiker Ebola virus Gabon great apes monitoring network outbreak prevention Research wildlife [DOI] 10.3201/eid1102.040533 PMC 바로가기
Late Recognition of SARS in Nosocomial Outbreak, TorontoDispatch Published on 2005-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] absence acute respiratory syndrome Clusters Contact dispatch Hospitalization Hospitalized hospitalized patient nosocomial Nosocomial infections outbreak postoperative Recognition recognize SARS Surveillance symptom onset Toronto underlying condition variety [DOI] 10.3201/eid1102.040607 PMC 바로가기 [Article Type] Dispatch
Quarantine for SARS, TaiwanResearch Published on 2005-02-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] 2003 acute respiratory syndrome compared Diagnosis Effect Effectiveness Emerging infectious disease Evidence faster found Hospitalization Infection infections infective Intervention investigated Isolation laboratory-confirmed led to measure Measures onset of symptom outbreak quarantine reducing Research SARS SARS patients SARS-coronavirus SARS-CoV screened significantly symptomatic Taiwan thought [DOI] 10.3201/eid1102.040190 PMC 바로가기 [Article Type] Research
Molecular mechanisms of severe acute respiratory syndrome (SARS)Review Published on 2005-01-202022-10-28 Journal: Respiratory Research [Category] Coronavirus, [키워드] acute respiratory syndrome approach caused contribute coronavirus Deleterious Effect effort Epidemics Features Genome Health immune immune system indirect effect infections Infectious disease Interaction Laboratory mechanism molecular mechanisms morbidity and mortality mutability Novel coronavirus Occurrence offer Open reading frame outbreak Pathogenesis Prevent pulmonary pathological Region required Research Respiratory disease SARS SARS-CoV severe Severe acute respiratory syndrome target cell the disease therapy vaccination Vaccine viral genome virulence virus widespread [DOI] 10.1186/1465-9921-6-8 PMC 바로가기 [Article Type] Review
Clinical evaluation of real-time PCR assays for rapid diagnosis of SARS coronavirus during outbreak and post-epidemic periodsArticle Published on 2004-12-012022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, [키워드] assays average clinical clinically suspected collected Course CoV detected Diagnosis disease Epidemic evaluate exhibited facilitated Germany highlight Hong Kong Laboratory lack nucleic acid extraction outbreak PCR assay PCR assays Positive predictive value protocol Rapid diagnosis Real-time PCR real-time PCR assay respiratory specimen reverse transcription RNA extraction Roche Roche Diagnostics RT-PCR SARS Coronavirus SARS CoV SARS epidemic SARS patient sensitivity serum sample shown specificity specimen specimens Stool tested the SARS epidemic Urine WHO [DOI] 10.1016/j.jcv.2004.09.029 PMC 바로가기 [Article Type] Article
Comprehensive detection and identification of human coronaviruses, including the SARS-associated coronavirus, with a single RT-PCR assayArticle Published on 2004-09-112022-11-01 Journal: Journal of virological methods [Category] Coronavirus, [키워드] acute respiratory syndrome Analysis analytical sensitivity Canada Comprehensive coronavirus described detect enzyme HCoV-229E HCoV-OC43 human coronaviruses other coronavirus outbreak provided RT-PCR assay SARS screening test Sequencing Specy Toronto virus [DOI] 10.1016/j.jviromet.2004.07.008 PMC 바로가기 [Article Type] Article
SARS Risk Perception, Knowledge, Precautions, and Information Sources, the NetherlandsDispatch Published on 2004-08-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] 2003 SARS acute respiratory syndrome dispatch information information sources knowledge Netherland outbreak Perception Precautionary behavior risk perceptions SARS severe [DOI] 10.3201/eid1008.040283 PMC 바로가기 [Article Type] Dispatch