Impact of obesity on survival in COVID-19 ARDS patients receiving ECMO: results from an ambispective observational cohortResearch Published on 2021-11-152022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome affected age Analysis ARDS ARDS patient arterial pH BMI Cohort Compliance coronavirus COVID-19 COVID-19 ARDS patient ECMO Extra-corporeal membrane oxygenation Health care system ICU identify Impact independent interquartile range IQR mechanical ventilation median multivariate logistic regression obesity Observational cohort study outbreak PaO Patient PEEP presenting Prognosis receiving Respiratory system Result risk factor SARS-CoV-2 severe ARDS severe COVID-19 supplementary material supported survival survival rate syndrome university hospital Ventilated [DOI] 10.1186/s13613-021-00943-0 PMC 바로가기 [Article Type] Research
Is endogenous carboxyhaemoglobin level a useful biomarker of clinical course and prognosis in COVID-19 patients?내인성 카르복시헤모글로빈 수치가 COVID-19 환자의 임상 경과 및 예후에 유용한 바이오마커입니까?Article Published on 2021-11-012022-09-11 Journal: International journal of clinical practice [Category] MERS, SARS, 바이오마커, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome Admission analysed Analysis ARDS Biomarker C-reactive protein caused Clinical course Comorbidities confirmed case correlation COVID-19 COVID-19 patient CRP D-dimer level D-dimer levels demographic data diagnosed with COVID-19 died emergency department ferritin Follow-up hospital identify laboratory parameter Macrophage macrophage activation syndrome morbidity morbidity and mortality Mortality Nasopharyngeal swab nasopharyngeal swab sample Older PaO Patient patients with ARDS PCR analysis Prognosis prothrombin Prothrombin time pulmonary disease pulmonary diseases Real-time PCR respiratory distress SARS-CoV-2 Significant significantly higher significantly lower Smokers syndrome treated Treatment treatment planning troponin Troponin-I university Wuhan Wuhan, China [DOI] 10.1111/ijcp.14680 PMC 바로가기 [Article Type] Article
Blood purification with CytoSorb in critically ill COVID-19 patients: A case series of 26 patients중환자 COVID-19 환자에서 CytoSorb를 사용한 혈액 정화: 26명의 환자에 대한 사례 시리즈Article Published on 2021-11-012022-09-11 Journal: Artificial organs [Category] MERS, SARS, 바이오마커, [키워드] (procalcitonin accompanied acute respiratory distress acute respiratory distress syndrome ARDS best C-reactive protein case sery Complication Confidence intervals coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill Cytokine storm Cytosorb effective expressed failure feasible ferritin form hemoadsorption hemodynamic hyperinflammation ICU Inflammatory intensive care intensive care unit knowledge Laboratory Lung function marker median moderate moderate ARDS Norepinephrine organ function PaO Patient patients with COVID-19 plasma concentration post treatment procalcitonin purification respiratory distress Respiratory distress syndrome Retrospective study SARS-CoV-2 positive patient SARS-CoV-2 positive patients Sepsis Sequential Organ Failure Assessment significant decrease significantly SOFA score survived syndrome therapy treated Treatment [DOI] 10.1111/aor.14024 PMC 바로가기 [Article Type] Article
Non-Randomized Trial of Dornase Alfa for Acute Respiratory Distress Syndrome Secondary to Covid-19Clinical Trial Published on 2021-10-202022-10-04 Journal: Frontiers in Immunology [Category] SARS, 임상, [키워드] 95% CI ARDS BALF Bronchoalveolar lavage fluid cleaving clinical clinical trial complexes COVID - 19 COVID-19 Degradation develop DNA Dornase alfa Effect Effects evaluate the effect Extracellular extracellular DNA fraction Genentech improvement Inhaled inhibited Lung compliance MPO NET NETs Neutrophil extracellular trap non-randomized oxygen oxygen saturation Oxygenation P-value PaO Patient patients with ARDS performed pilot study Pneumonia positive reduction in Registration respiratory Respiratory failure Result secondary to Severe case Structure sustained therapy treatment group Viral [DOI] 10.3389/fimmu.2021.714833 PMC 바로가기 [Article Type] Clinical Trial
Severe Patients With ARDS With COVID-19 Treated With Extracorporeal Membrane Oxygenation in China: A Retrospective StudyMedicine Published on 2021-10-202022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress affecting ARDS Characteristics China Clinical features Complication Coronavirus (COVID-19) country COVID-19 COVID-19 patient COVID-19 patients died ECMO Extracorporeal Extracorporeal membrane oxygenation (ECMO) Health increased survival increasingly management membrane Mortality negative non-survivor novel coronavirus disease outcome Oxygenation pandemic PaO Patient patients poor prognosis recruited required Respiratory failure Retrospective study Severe acute respiratory syndrome Support survival rate survived survivor syndrome those who survived treated Treatment variable ventilator parameters [DOI] 10.3389/fmed.2021.699227 PMC 바로가기 [Article Type] Medicine
Plasma endostatin correlates with hypoxia and mortality in COVID-19-associated acute respiratory failureClinical Trial Published on 2021-10-202022-10-04 Journal: Biomarkers in Medicine [Category] MERS, SARS, 임상, [키워드] 30-Day mortality acute respiratory distress Admission Analysis analyzed Angiogenesis ARDS arterial oxygen tension association Biomarker Blood C-reactive protein characteristic Characteristics collected correlated COVID-19 Cutoff D-dimer demographic disease severity endostatin Endothelial dysfunction endothelial injury ferritin hypoxia IL-6 Inflammation inhibitor intensive care Kaplan–Meier analysis Lactate medical records Mortality PaO Pathogenesis Patient plasma predict probability of survival pulmonary disease pulmonary injury quantification receiving Respiratory failure resulting Sample sensitivity Severe COVID-19 Infection specificity survival survivor syndrome upregulated was used [DOI] 10.2217/bmm-2021-0111 PMC 바로가기 [Article Type] Clinical Trial
Feasibility of CPAP application and variables related to worsening of respiratory failure in pregnant women with SARS-CoV-2 pneumonia: Experience of a tertiary care centreClinical Trial Published on 2021-10-192022-10-04 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] Admission adverse events applied ARF assessment C reactive protein Care chest X-ray Cohort Continuous CPAP distress distribution Endotracheal intubation experience feasibility feasible fraction hospitalised hypoxemic lobes outcome oxygen oxygen only oxygen supplementation Oxygenation pandemic PaO Patient patients with COVID-19 positive airway pressure pregnant women Prevent Respiratory failure retrospective Safe SARS-CoV-2 SARS-CoV-2 pneumonia serum significantly variable worsening [DOI] 10.1371/journal.pone.0258754 PMC 바로가기 [Article Type] Clinical Trial
Data automated bag breathing unit for COVID-19 ventilator shortagesCOVID-19 인공호흡기 부족에 대한 데이터 자동화 백 호흡 장치Research Articles Published on 2021-10-182022-09-10 Journal: Intensive Care Medicine Experimental [Category] 비임상, [키워드] ABBU acute respiratory distress syndrome Acute respiratory failure Adult patients animal model arterial blood arterial blood gases assist automated Bag Bag valve resuscitator baseline Bench breath breathing caused changes in clinical trial Compliance COVID-19 COVID-19 pandemic development Efficacy Emergency resuscitator etiology fixed followed by fraction injured lung Injury lung Lung injury lung lavage mechanical ventilator minute ventilation output oxygen oxygen flow oxygen flow rate Oxygenation PaO parameter Patient PEEP Physiological levels PIGS provide respiratory Respiratory failure respiratory rate Result saline lavage Tidal volume Treatment unit Ventilation ventilator Ventilator shortage Volume was increased was tested weight were measured [DOI] 10.1186/s40635-021-00419-2 PMC 바로가기 [Article Type] Research Articles
PaO 2 /FiO 2 ratio forecasts COVID-19 patients’ outcome regardless of age: a cross-sectional, monocentric studyIm - Original Published on 2021-10-122022-10-04 Journal: Internal and Emergency Medicine [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] 95% CI Atypical pneumonia AUC calculated clinical clinical outcomes Cohort COVID-19 cross-sectional cut-off value develop highlight identify indicated indication Inflammatory LDH NLR outcome overlapped oxygen support pandemic PaO PaO2/FiO2 ratio parameter Patient Population Predictive recruited Registered SARS-CoV-2 SARS-CoV-2-infected patients score sensitivity severe disease severe respiratory failure specificity supplementary material supportive therapies Trial validation cohort with mild disease World Health Organization [DOI] 10.1007/s11739-021-02840-7 PMC 바로가기 [Article Type] Im - Original
Open-label randomized controlled trial of ultra-low tidal ventilation without extracorporeal circulation in patients with COVID-19 pneumonia and moderate to severe ARDS: study protocol for the VT4COVID trialCOVID-19 폐렴 및 중등도에서 중증 ARDS 환자에서 체외 순환이 없는 초저 일회 호흡 호흡의 공개 라벨 무작위 대조 시험: VT4COVID 시험을 위한 연구 프로토콜Study Protocol Published on 2021-10-112022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 acute respiratory distress syndrome Adult patient Adult patients all-cause mortality Analysis analyzed ARDS block body weight circulation complication of COVID-19 consumables control group COVID-19 COVID-19 pneumonia criterion data-driven defined distress eligible extracorporeal circulation groups Inclusion intensive care intensive care unit intention-to-treat intervention group Invasive mechanical ventilation less Lung injury manuscript mechanical ventilation Mild moderate Mortality mortality rate outcomes PaO Patient patients with COVID-19 Pneumonia predicted Prevent Primary outcome Protective random randomization list Randomized Randomized controlled trial recruitment reduce respiratory distress Respiratory distress syndrome SARS-CoV-2 selective severe ARDS stratified Study protocol supplementary material syndrome Tidal volume Transparency treat Trial Trial registration Ultra-low tidal volume ventilation Ultraprotective ventilation Ventilated Ventilation ventilator ventilator-free day Ventilator-free days Volume worldwide pandemic [DOI] 10.1186/s13063-021-05665-z PMC 바로가기 [Article Type] Study Protocol