Charlson comorbidity index, neutrophil-to-lymphocyte ratio and undertreatment with renin-angiotensin-aldosterone system inhibitors predict in-hospital mortality of hospitalized COVID-19 patients during the omicron dominant periodArticle Published on 2022-08-252022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] 95%CI absence analyzed Angiotensin-converting enzyme angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers ARBs blocker Care CCI Charlson comobidity index clinician Comorbidity Coronavirus disease 2019 COVID-19 COVID-19 patient cut-off value died discharged dominant echocardiographic Endpoint greater help high-risk patient Hospital admission Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized patient in-hospital mortality Infection inhibitor Laboratory laboratory-confirmed males Mortality mortality risk Neutrophil-to-lymphocyte ratio NLR Older omicron Patient physical predict predicted predictor Prevalence prognostic indicator Radiographic receptor reduce risk stratification significantly the primary endpoint therapy [DOI] 10.3389/fimmu.2022.958418 PMC 바로가기
Clinical manifestations and disease severity of SARS-CoV-2 infection among infants in Canada캐나다 영유아에서 SARS-CoV-2 감염의 임상 증상 및 질병 중증도Article Published on 2022-08-242022-09-11 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] absence acute COVID-19 age approved Asymptomatic Canada Care Characteristics Clinical management clinical manifestation clinical manifestations clinics Cohort comorbid condition comorbid conditions condition coryza cough COVID-19 criteria defined disease severity Fever help higher odd higher odds Hospitalization Hospitalized identify incidentally detected Infant Infants Infrastructure initial Inpatient Logistic regression main analysis microbiologically Mild moderate moderate or severe disease multivariable logistic regression National oral intake outcome Outpatient outpatients patient with SARS-CoV-2 presenting symptom Program Prospective Study Public health interventions reported SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severe disease severity strain Vaccine was performed [DOI] 10.1371/journal.pone.0272648 PMC 바로가기 [Article Type] Article
Impact of Coronavirus Disease 2019 (COVID-19) on Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis Prescriptions in the United States-A Time-Series Analysis코로나바이러스 질병 2019(COVID-19)가 인간 면역결핍 바이러스(HIV)에 미치는 영향 미국의 사전 노출 예방 처방-시계열 분석Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] 치료제, [키워드] 95% CI absence affected Algorithm analyzed COVID-19 COVID-19 pandemic database decrease FDA approval greater highlighting HIV Human Impact Intervention maintain National Observed occurred outcome pandemic pre-exposure prophylaxis predicted PrEP prescription Prophylaxis quantified rate ratio reduction the United State The United States United States uptake [DOI] 10.1093/cid/ciac038 PMC 바로가기 [Article Type] Article
Factors Affecting the Self-Isolation Monitoring Program for COVID-19 Patients at the Universitas Indonesia HospitalArticle Published on 2022-08-242022-11-16 Journal: Journal of Environmental and Public Health [Category] SARS, 변종, [키워드] absence administration Admission ALT Analysis Antibiotics Characteristics condition conducted COVID-19 COVID-19 patient cross-sectional determine Effectiveness electronic medical records evaluate Factor hospital increase in Indonesia MONITOR monitoring observé occurred outbreak outcome outcomes pandemic Patient patients performed Program provided risk factor Self-isolation service Shortness of breath significantly Stage suggested Symptoms the patient variant was performed with COVID-19 [DOI] 10.1155/2022/2297328 PMC 바로가기
In silico investigation and potential therapeutic approaches of natural products for COVID-19: Computer-aided drug design perspectiveArticle Published on 2022-08-222022-11-16 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 신약개발, [키워드] absence acute respiratory syndrome alkaloids analyzed anti-SARS-CoV-2 approach approved assist binding binding energy caused Clinicians Compound computer-aided drug design contribute coronavirus COVID-19 death derivative determine Diseases drug candidate drug design Drug discovery drugs effective facilitate highest in silico Ligand mechanism Medicines natural natural products Perspective pharmacological physician phytochemical Practitioner public health RdRP reported Research researcher researchers RNA polymerase Safe SARS-CoV-2 SARS-CoV-2 main protease subsequent therapeutic Therapeutic approach therapeutic molecules therapeutic target took place Toxicity Treatment vaccination viral replication Virtual screening [DOI] 10.3389/fcimb.2022.929430 PMC 바로가기
Pathogen Profile of Children Hospitalised with Severe Acute Respiratory Infections during COVID-19 Pandemic in the Free State Province, South Africa남아프리카 공화국 프리 스테이트 주에서 COVID-19 팬데믹 기간 동안 중증 급성 호흡기 감염으로 입원한 어린이의 병원체 프로필Article Published on 2022-08-212022-09-11 Journal: International Journal of Environmental Research an [Category] SARS, 치료기술, 치료제, [키워드] absence Acute respiratory infection acute respiratory infections acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aetiology change children circulation Co-infection collected complicate contribute coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 transmission Ct values detection rate Diagnosis exacerbated Free Immunity infection control Influenza Influenza virus measure Mortality negativity Panel pathogen Pathogens profile QIAstat-Dx® Respiratory SARS-CoV-2 Panel respiratory respiratory infections respiratory pathogen Respiratory pathogens respiratory syncytial virus respiratory virus respiratory viruses SARI SARS-CoV-2 severe acute respiratory infections severe acute respiratory syndrome Coronavirus Severe infection severe infections South Africa state susceptibility Swab Treatment Viral detection virus waned Waves waves of COVID-19 pandemic. [DOI] 10.3390/ijerph191610418 PMC 바로가기 [Article Type] Article
Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil Research Published on 2022-08-182022-10-05 Journal: Nature Microbiology [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] absence Brazil characterized country COVID-19 case death effective Epidemic Epidemiology Europe Evidence Gamma Genome genomic Latin America Lineage Local Measures National P.1 P.2 pandemic progressed SARS-CoV-2 SARS-CoV-2 variants Spread Surveillance sustained the epidemic the SARS-CoV-2 Transmission transmission cluster variant variants of concern viral lineage virus transmission [DOI] 10.1038/s41564-022-01191-z [Article Type] Research
Effect of Ultra-Micronized Palmitoylethanolamide and Luteolin on Olfaction and Memory in Patients with Long COVID: Results of a Longitudinal StudyRandomized Controlled Trial Published on 2022-08-172022-10-05 Journal: Cells [Category] 임상, [키워드] absence affected age ameliorated Anosmia average baseline Biomarkers Brain brain fog Combination COVID COVID-19 disorders Effect group Hyposmia interval investigated Long long-haul COVID syndrome longitudinal lutein Luteolin measure mechanisms memory men Mental mental clouding Neuroinflammation Olfaction olfactory olfactory dysfunction olfactory threshold olfactory training outcomes palmitoylethanolamide parosmia Patient patients PEA-LUT Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) Prevalence qualitative smell disorders Quantitative Randomized receive recruited reduction in regimen remaining group Result SARS-COV-2 infection self-report measure severity smell disorders. subjects subsequent therapy thresholds Treatment were assessed women [DOI] 10.3390/cells11162552 PMC 바로가기 [Article Type] Randomized Controlled Trial
Monoclonal antibodies for mild-to-moderate COVID-19 in multiple sclerosis: A case series다발성 경화증에서 경증에서 중등도의 COVID-19에 대한 단일클론항체: 사례 시리즈Article Published on 2022-08-152022-09-12 Journal: Journal of the neurological sciences [Category] MERS, 진단, 치료제, [키워드] absence anti-CD20 anti-SARS-CoV-2 antibody case sery change COVID-19 COVID-19 vaccine disease FIVE Mild-to-moderate monoclonal antibodies monoclonal antibody Multiple multiple sclerosis reduced reported symptomatic treated Treatment [DOI] 10.1016/j.jns.2022.120306 PMC 바로가기 [Article Type] Article
Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infectionOmicron BA.4/BA.5 탈출 중화 면역 BA.1 감염Article Published on 2022-08-102022-09-11 Journal: Nature Communications [Category] SARS, 변종, 진단, 치료기술, [키워드] absence B.1.1.529 change Decline decrease elicited fold Immunity individuals infected individuals Infection lineages neutralization neutralizing immunity omicron Receptor binding domain SARS-CoV-2 selective South Africa Spike receptor binding domain subsequent Substitution substitutions the strongest vaccinated individual vaccinated individuals vaccination virus Virus neutralization viruses [DOI] 10.1038/s41467-022-32396-9 PMC 바로가기 [Article Type] Article