Current Paradigm of Hepatitis E Virus Among Pediatric and Adult PatientsArticle Published on 2021-09-302023-08-30 Journal: Frontiers in Pediatrics [Category] E형 간염, [키워드] Adult patients Antiviral treatment hepatitis E virus Pediatric patients prevention [DOI] 10.3389/fped.2021.721918 PMC 바로가기
Use of Telemedicine to Expedite and Expand Care During COVID-19COVID-19 기간 동안 치료를 신속하고 확장하기 위한 원격 의료 사용Endemic Infections Published on 2021-09-192022-09-12 Journal: Western Journal of Emergency Medicine [Category] MERS, SARS, 진단, [키워드] Admission Adult patients Care center coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic death Descriptive statistics effective emergency department Healthcare system Healthcare systems Hospitalization Intubated intubation Novel coronavirus novel coronavirus disease one patient outcome Patient performed Program reducing required Result Retrospective study risk Rush University Medical Center Safe Seven subsequent Telemedicine telemedicine visit telemedicine visits treat university vulnerable patients [DOI] 10.5811/westjem.2021.4.51317 PMC 바로가기 [Article Type] Endemic Infections
Early versus late awake prone positioning in non-intubated patients with COVID-19COVID-19를 가진 intubated 환자에서 조기 대 늦게 깨어있는 낙인 위치Randomized Controlled Trial Published on 2021-09-172022-08-13 Journal: Critical Care [Category] 임상, [키워드] 28-day mortality Acute hypoxemic respiratory failure Adult patient Adult patients advanced age age app Awake prone positioning ClinicalTrials.gov NCT04325906 collected coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients defined HFNC High-flow nasal cannula Hydrocortisone hypoxemic Hypoxemic respiratory failure IMPROVE increased mortality initiated intubation intubation rate lower mortality male management median time nasal nasal cannula NCT04325906 no difference Non-intubated non-intubated patient outcome Patient per day post-hoc analysis Primary outcomes prone positioning Randomized controlled trial Respiratory failure Result secondary to survival Trial registration with COVID-19 [DOI] 10.1186/s13054-021-03761-9 PMC 바로가기 [Article Type] Randomized Controlled Trial
Epidural morphine in COVID ARDS patients with high respiratory drive: a structured summary of a study protocol for a randomised controlled trial높은 호흡 드라이브가 있는 COVID ARDS 환자의 경막외 모르핀: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-09-162022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 28-day mortality Abnormalities acceptance administer Administered Admission Adult patient Adult patients allocation ARDS patient aseptic technique assistant average blind Blinding both group both groups catheterization Coagulation comparator Patients control group COVID COVID 19 patient COVID 19 patients COVID-19 criteria CTRI death discharge dissemination dose doses double blind Dyspnoea element Endotracheal intubation Epidural epidural catheter Epidural morphine epidural space Escalation exclusion criteria fixed fraction greater Group allocation HCO hypoventilation Hypoxemia ICU ICU patient inclusion criteria India injection Intervention intervention group intubation involved list Local maximum mechanical ventilation Medical Science Medical Sciences Metabolic acidosis minimum morphine morphine sulphate Mortality NIV non-invasive ventilation number Nurse objective outcome Pain parameters participant Patient Patient self-induced lung injury patients with COVID19 physician Placebo protocol random randomisation randomised randomised controlled trial recruited reduce Registered registry Research respiratory respiratory acidosis Respiratory drive respiratory parameters resulting Sample size sealed second dose secondary Secondary outcomes Sedation Sepsis severe hypoxemia sitting position skin Source Study protocol sulphate supplementary material team the patient Trial ventilator parameters website with COVID-19 [DOI] 10.1186/s13063-021-05570-5 PMC 바로가기 [Article Type] Letter
Intravenous immunoglobulin as an important adjunct in the prevention and therapy of coronavirus 2019 disease코로나바이러스 2019 질병의 예방 및 치료에 중요한 보조제로서의 정맥 면역글로불린Review Published on 2021-09-162022-09-10 Journal: Scandinavian journal of immunology [Category] MERS, SARS, 진단, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adult patients affected attenuate Autoimmune disease Autoimmune diseases Autoimmunity benefit caused clinically contributing to control group control groups coronavirus coronavirus 2019 disease coronavirus disease Coronavirus disease‐19 Corticosteroids COVID‐19 COVID‐19 patients COVID‐19 COVID‐19 vaccination Critically ill Cytokines disease early administration Evidence heterogeneity ICU Immunoglobulin immunomodulation immunotherapies Immunotherapy in some Intravenous immunoglobulin IVIG lack limitation Long‐COVID lung mechanical ventilation mechanism morbidity and mortality New coronavirus outcome pandemic pathogenic Patient patients Post‐COVID presenting Pulmonary function rapid response reduce reduction in mortality respiratory SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus severe disease syndrome target the disease therapy Treatment vaccination Vascular vascular system [DOI] 10.1111/sji.13101 PMC 바로가기 [Article Type] Review
Lack of effect on in-hospital mortality of drugs used during COVID-19 pandemic: Findings of the retrospective multicenter COVOCA studyCovid-19 Pandemic 동안 사용되는 약물의 병원 사망률에 미치는 영향 부족 : 후 향적 Multicenter Covoca 연구 결과Observational Study Published on 2021-09-142022-09-10 Journal: PLoS ONE [Category] MERS, 임상, 치료제, [키워드] administration Adult patients Antibiotics Anticoagulants Antiviral association Campania Clinical outcome Clinical practice COVID COVID-19 COVID-19 pandemic cumulative cumulative mortality cut-off database described drug Drug administration drugs early treatment Effect effective finding Hospitalization hospitalized patient hospitalized patients Hydroxychloroquine In-hospital in-hospital mortality incidence intubation Italy knowledge Mortality MOST multicenter Multivariable models non-invasive ventilation Observational cohort study orotracheal intubation outcome pandemic Patient regimen Region Result retrospective retrospective observational cohort study SARS-COV-2 infection significantly the disease therapeutic therapy Tocilizumab Treatment Usage [DOI] 10.1371/journal.pone.0256903 PMC 바로가기 [Article Type] Observational Study
Comparative therapeutic efficacy of interferon alfa-2b and combination lopinavir/ritonavir plus interferon alfa-2b against SARS-CoV-2SARS-COV-2에 대한 인터페론 ALFA-2B 및 조합 Lopinavir/Ritonavir Plus 인터페론 ALFA-2B의 비교 치료 효능Research Article Published on 2021-08-302022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료제, [키워드] Adult patients adverse event adverse events antiviral drug antiviral drugs assigned association benefit clearance Clinical characteristics clinical monitoring Combination Comparative confidence interval coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 Cox proportional hazard Cox proportional hazards regression disease Efficacy and safety evaluate faster group incidence individual Infection interferon interferon alfa-2b Lopinavir Lopinavir/ritonavir Nasopharyngeal swab no significant difference no significant differences not significantly different outbreak outcome oxygen oxygen support Patient patients hospitalized patients with SARS-CoV-2 PCR Pneumonia primary endpoint primary endpoints public health required Result retrospective cohort study Ritonavir SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) significant differences standard care group standard supportive care Symptom therapeutic efficacy therapy three group three groups Treatment treatment guideline treatment guidelines triggered virus virus clearance were assessed with COVID-19 [DOI] 10.1186/s12879-021-06595-6 PMC 바로가기 [Article Type] Research Article
Clinical validation of an open-access SARS-COV-2 antigen detection lateral flow assay, compared to commercially available assays상업적으로 이용 가능한 분석법과 비교하여 개방 액세스 SARS-COV-2 항원 검출 측면 흐름 분석의 임상 적 검증Comparative Study Published on 2021-08-172022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, 치료제, [키워드] Adult patient Adult patients antigen detection clinical Clinical sign Clinical signs COVID-19 diagnostic Infection lateral flow meet minimum nare nasopharyngeal pandemic positive Predictive Rapid Rapid test Rapid tests reagents Result RT-qPCR SARS-COV-2 infection Signs and symptoms Symptom Symptoms WHO [DOI] 10.1371/journal.pone.0256352 PMC 바로가기 [Article Type] Comparative Study
The first newborn patient with SARS-CoV-2 variant B.1.1.7 identified in Viet Nam: treatment and care practicesSARS-COV-2 변이체를 가진 최초의 신생아 B.1.1.7 베트남에서 확인 : 치료 및 치료 관행Case Reports Published on 2021-08-162022-09-10 Journal: Western Pacific Surveillance and Response Journal [Category] MERS, SARS, 변종, 치료기술, [키워드] Admission Adult patients B.1.1.7 B.1.1.7 variant breastmilk Care Child Clinical characteristics clinical feature Clinical features clinical symptom Contact tracing cough country COVID-19 described diarrhoea digestive discharge during treatment equipment Great Britain hand sanitizer Hospitalization infected with SARS-CoV-2 information Ireland Medical mask medical masks mother mother and child Newborn no symptom no symptoms on admission Patient patient with SARS-CoV-2 patients Personal protective equipment preventive measure preventive measures productive cough provided receive runny nose SARS-CoV-2 SARS-CoV-2 variant Spread Symptom Symptoms tested the patient these symptoms Treatment United Kingdom variant vomiting was used while [DOI] 10.5365/wpsar.2021.12.2.008 PMC 바로가기 [Article Type] Case Reports
Prolonged in-hospital stay and higher mortality after Covid-19 among patients with non-Hodgkin lymphoma treated with B-cell depleting immunotherapyB 세포 고갈 면역 요법으로 치료받은 비호지킨 림프종 환자의 코비드-19 이후 입원 기간 연장 및 사망률 증가Multicenter Study Published on 2021-08-012022-09-11 Journal: American journal of hematology [Category] MERS, SARS, 바이오마커, 진단, [키워드] 95% confidence interval administration Adult patient Adult patients age analyzed anti-CD20 anti-CD20 therapy B-cell contribute death deficiency depleting determinant disease Efficacy Follow-up French hazard ratio higher risk hospital Hospitalization immune immune deficiency Immunotherapy In-hospital Length LOS lymphoma management median median age Mortality multivariable analyses Non-Hodgkin Lymphoma outcomes overall survival pandemic Patient patients patients hospitalized Prolonged question raise risk factor Risk factors subdistribution Support survival therapeutic approaches treated vaccination [DOI] 10.1002/ajh.26209 PMC 바로가기 [Article Type] Multicenter Study