Non-COVID-19 patients in times of pandemic: Emergency department visits, hospitalizations and cause-specific mortality in Northern ItalyResearch Article Published on 2021-03-222022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adjust all age group Care cause-specific mortality caused conducted consequence COVID-19 COVID-19 pandemic death Department described Diagnosis Diseases driven by dropped early phase Emergency emergency department Endocrine Endocrine diseases groups healthcare healthcare service Healthcare system Hospitalization hospitalizations increase in Italian Italy lockdown Mortality neoplasm Neoplasms non-COVID-19 patient Non-COVID-19 patients pandemic Patient recorded reduced reduction retrospective severity significant increase Weekly [DOI] 10.1371/journal.pone.0248995 PMC 바로가기 [Article Type] Research Article
Interventions for treatment of COVID-19: Second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)COVID-19 치료를 위한 중재: 메타 분석 및 시험 순차 분석이 포함된 살아있는 체계적인 검토의 두 번째 판(The LIVING 프로젝트)Meta-Analysis Published on 2021-03-112022-08-13 Journal: PLoS ONE [Category] Biochemistry, SARS, 임상, 진단, 치료제, [키워드] 95% CI 95% confidence interval adjusted Admission aggregate data meta-analyses all age group all age groups all-cause mortality Analysis boundary bromhexine caused certainty certainty of evidence Clinical research Clinical significance Cochrane guidelines comparison Comparisons Corticosteroid Corticosteroids COVID-19 database Effect Effects eight events Evidence evidence of Families FIVE Fixed-effect meta-analysis futility GRADE high risk Hydroxychloroquine Immunoglobulin indicate indication indications individual patient data meta-analyses individuals information intensive care Intervention effects intravenous Intravenous immunoglobulin lack life Lopinavir Lopinavir-ritonavir mechanical ventilation meta-analyses Meta-analysis moderate Network meta-analysis no evidence of non-serious adverse non-serious adverse events on mechanical ventilation outcome outcomes participant Participants patient data performed Primary outcomes PRISMA Quality of life random error random errors random-effects meta-analyses randomized clinical trial randomized clinical trials rapidly spreading disease reached reduce reduced Remdesivir renal replacement therapy replacement therapy required Research risk risk of death risk ratio risks of bia Ritonavir searched second secondary Secondary outcomes sequential analysis Serious Adverse Event Serious Adverse Events single trial standard care statistically significant systematic review threshold Tocilizumab Treatment treatment for COVID-19 treatment intervention treatments of COVID-19 Trial Trial methodology trial sequential analyses trial sequential analysis website with COVID-19 [DOI] 10.1371/journal.pone.0248132 PMC 바로가기 [Article Type] Meta-Analysis
Future scenarios for the SARS-CoV-2 epidemic in Switzerland: an age-structured modelBrief Report Published on 2021-03-112022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] age all age group applied cause children compartmental model Contact Course COVID-19 Critical Epidemic expected Future groups increased risk intensive care Intervention lifting mathematical model measure reduction reduction in resulting SARS-CoV-2 SARS-CoV-2 transmission selected suppressed Switzerland the epidemic the SARS-CoV-2 [DOI] 10.12688/f1000research.24497.2 PMC 바로가기 [Article Type] Brief Report
A Cross-Country Examination on the Fear of COVID-19 and the Sense of Loneliness during the First Wave of COVID-19 OutbreakArticle Published on 2021-03-052022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] age age and gender all age group Analysis complex country COVID-19 COVID-19 outbreak COVID-19 pandemic Croatia Cross-country death emotional examination fear Fear of COVID-19 female Future Gender greater group groups help Infection Italian Italy less lockdown loneliness male measure mental health issue Mild participant Psychosocial distress rate of infection reported Research risk sense Slovakia Slovenia Spain Spanish Spread Symptom Wave [DOI] 10.3390/ijerph18052586 PMC 바로가기 [Article Type] Article
Understanding Concerns, Sentiments, and Disparities Among Population Groups During the COVID-19 Pandemic Via Twitter Data Mining: Large-scale Cross-sectional StudyOriginal Paper Published on 2021-03-052022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] 95% CI addition age all age group analyses Analysis analyzed approach attributes collected Concerns conducted COVID-19 COVID-19 pandemic cross-sectional Depression Disparities disparity effective English Evolution expressed female FIVE Github group groups Health identify Impact individuals infodemiology infoveillance less lowest male males objective Odds ratio Older organization pandemic Penetrating population group population groups positive public health released Research Result sentiments significantly significantly more study period Support Twitter mining understanding Via [DOI] 10.2196/26482 PMC 바로가기 [Article Type] Original Paper
Evaluation of serum ferritin for prediction of severity and mortality in COVID-19- A cross sectional studyCross-sectional Study Published on 2021-02-122022-10-04 Journal: Annals of Medicine and Surgery [Category] 바이오마커, [키워드] all age group all-cause mortality Analysis analyzed association Binary logistic regression category characteristic Chemical Concentration conducted Coronavirus disease 2019 COVID-19 COVID-19 cases cross Department evaluated females ferritin Final genders hospitalized patient Hypothesis identify in-patient independent Karachi Logistic regression male material medical record Medicine Mortality Non-survivors Patient positive Prognosis prognostic prognostic biomarker Result ROC analysis Science Serum ferritin severe severity significant difference SPSS Statistical Package subject survivor tested total body university utility variable was used were recorded with COVID-19 [DOI] 10.1016/j.amsu.2021.02.009 PMC 바로가기 [Article Type] Cross-sectional Study
Inosine Pranobex Significantly Decreased the Case-Fatality Rate among PCR Positive Elderly with SARS-CoV-2 at Three Nursing Homes in the Czech RepublicCommunication Published on 2020-12-162022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] acute respiratory viral infection affected age all age group Case-fatality rate CFR COVID-19 COVID-19 pandemic COVID-19 patients Czech Republic Decreased demonstrated effective elderly Epidemic home inosine pranobex Ireland Natural killer cells Nursing nursing homes Odds ratio PCR Rate reduced SARS-CoV-2 significant difference significantly statistically significant tested the SARS-CoV-2 virus Treatment Trial viral respiratory infections [DOI] 10.3390/pathogens9121055 PMC 바로가기 [Article Type] Communication
Interventions for treatment of COVID-19: A living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)COVID-19 치료를 위한 중재: 메타 분석 및 시험 순차 분석을 통한 살아있는 체계적인 검토(The LIVING Project)Research Article Published on 2020-09-172022-08-13 Journal: PLoS Medicine [Category] Biochemistry, COVID-19, SARS, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus Admission adverse event adverse events aggregate data meta-analyses all age group all age groups all-cause mortality assessment caused certainty certainty of evidence Clinical effect Clinical research Clinical significance clinical trials Cochrane guidelines Comparisons conducted convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients database development Dexamethasone driven by Effect Evidence evidence of experimental intervention Families GRADE high risk Hydroxychloroquine individual patient data meta-analyses individuals Infection intensive care International Intervention Intervention effects item Juul lack life Lopinavir Lopinavir–ritonavir mechanical ventilation meta-analyses Meta-analysis Network meta-analysis no effect no effects no evidence of nonserious adverse event nonserious adverse events on mechanical ventilation outbreak outcome outcomes participant Participants Patient patient data paucity of data performed Placebo Primary outcomes Quality of life random errors random-effects meta-analyses randomized clinical trial randomized clinical trials rapidly spreading disease rate ratio reduce reduced reducing Remdesivir renal replacement therapy replacement therapy Reporting Research researcher respiratory Respiratory failure review risk risk of bia risk of death risk ratio Ritonavir SARS-CoV-2 searched secondary Secondary outcomes Serious Adverse Event Serious Adverse Events severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 single trial single trial randomizing Sophie Spread standard care statistically significant systematic review systematic reviews Treatment treatment for COVID-19 treatment intervention treatment of COVID-19 treatments for COVID-19 treatments of COVID-19 Trial Trial methodology trial randomizing trial sequential analyses trial sequential analysis website with COVID-19 [DOI] 10.1371/journal.pmed.1003293 PMC 바로가기 [Article Type] Research Article
Does severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cause orchitis in patients with coronavirus disease 2019 (COVID-19)?Research Article Published on 2020-08-112022-10-28 Journal: Arab Journal of Urology [Category] COVID-19, [키워드] acute respiratory syndrome age all age group association clinical symptom collected coronavirus coronavirus disease Coronavirus-2 COVID-19 disease severity disease status enzyme excluded Follow-up group hospital Hypothesis identify immunodeficiency information IRB male molecular observé orchitis Patient patients patients with COVID-19 polymerase chain Prevalence protease retrospective review SARS-CoV-2 Serine Symptom transcriptase transmembrane White blood cell with COVID-19 [DOI] 10.1080/2090598X.2020.1798862 PMC 바로가기 [Article Type] Research Article
Contriving Multi-Epitope Subunit of Vaccine for COVID-19: Immunoinformatics ApproachesImmunology Published on 2020-07-282022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] adaptation all age group Amino acid B cell B cells beta coronavirus binding epitope C-terminal can be used caused codon complex COVID-19 CTL CTL epitope cytotoxic T lymphocyte determine domains EAAAK linker Efficacy ENhance epitope Epitope prediction evaluated experiment experimental validation expression Fatality rate Final functional fusing help histocompatibility complex HTL Immune receptor immunoinformatics immunoinformatics approach in silico In silico cloning Incubation period linkers MHC-I MHC-II molecular docking mRNA Multi-epitope vaccine N-terminal performed positive predicted Prevalence producing Protein public health reduce RNA SARS-CoV-2 SARS-CoV-2 infections secondary structure sequence single-stranded susceptible T lymphocyte TAT the vaccine tlr-3 Treatment Vaccine virus vital role β-defensin [DOI] 10.3389/fimmu.2020.01784 PMC 바로가기 [Article Type] Immunology