Search like an expert: Reducing expertise disparity using a hybrid neural index for COVID-19 queriesResearch article Published on 2022-03-012022-10-05 Journal: Journal of biomedical informatics [Category] COVID19(2023년), SARS, 바이오마커, [키워드] alleviate Biomedical search comparable consumer COVID-19 Degradation Dense retrieval document Effectiveness evaluate extension index model information Information retrieval knowledge lack Medical misinformation natural language processing Neural index reduce reducing resources retrieved Universal sentence embeddings [DOI] 10.1016/j.jbi.2022.104005 [Article Type] Research article
Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors새로운 당화 기반 치료제 - 글리옥살라제 1 유도제 및 글리옥살라제 1 억제제Review Published on 2022-02-232022-09-10 Journal: International Journal of Molecular Sciences [Category] 비임상, [키워드] Activation active against aging alleviate apoptotic appear Breast cancer breath cancer chemotherapy Cell cell line Chemotherapy clinical impact clinical trial clinically Combination Complication contribute correction diabetes dicarbonyl stress disease DNA double-blind dysfunction evaluated expression Glioblastoma glioblastoma multiforme Glo1 Glycation glyoxalase hesperetin IMPROVE in vitro in vivo inactivation Increased induce inducer inhibitor insulin insulin resistance low-grade inflammation malaria metabolism methylglyoxal mice multidrug-resistant National Cancer Institute obese outcome outcomes pathogenic Placebo placebo-controlled Protein Proteins prototype Randomized resveratrol SARS-CoV-2 small molecule spliceosome Stress subjects survival therapeutic therapy Treatment Tumor tumor cell line tumors type 2 diabete type 2 diabetes unfolded protein response Vascular [DOI] 10.3390/ijms23052453 PMC 바로가기 [Article Type] Review
The Impact of SARS-CoV-2 Primary Vaccination in a Cohort of Patients Hospitalized for Acute COVID-19 during Delta Variant PredominanceArticle Published on 2022-02-232022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute COVID-19 age alleviate association Breakthrough infection Comorbidities Comorbidity COVID-19 COVID-19 outcome COVID-19 patients COVID-19 vaccine death Delta delta variant discharged duration of hospitalization effective intervention enrolled European evaluate hospital Hospitalization Hospitalized Immunocompromised Impact mechanical ventilation median age men morbidity and mortality mRNA-1273 Older Patient patients patients hospitalized PCR-confirmed progression SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine severe disease Sex Slovenia symptom onset vaccination Vaccine breakthrough with COVID-19 [DOI] 10.3390/jcm11051191 PMC 바로가기 [Article Type] Article
Impact of a resident and student-led video visitation navigation programResearch Published on 2022-02-192022-10-28 Journal: BMC Medical Education [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] alleviate Anxiety Care conducted connection contribute COVID-19 COVID-19 pandemic demonstrated facilitate facilitated hospital Hospitalized Impact IMPROVE involved mechanism mitigate objective pandemic Patient Patient support persons provided Quality improvement resident Result Stress supplementary material Support survey telehealth the patient the SARS-CoV-2 Trainee engagement [DOI] 10.1186/s12909-022-03172-6 PMC 바로가기 [Article Type] Research
Trained Immunity: An Overview and the Impact on COVID-19Immunology Published on 2022-02-172022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] activate alleviate approach B-glucan Bacillus BCG cell type cells clinical study clinical trials component Corona COVID-19 COVID-19 crisis COVID-19 pandemic develop disease pathogenesis effective greater Health immune immune protection immune response immune system Immunity Impact in vitro in vivo Infection Infectious disease innate immune cell innate immune system Innate immunity involved LPS mechanism monocyte Monocytes natural killer natural killer (NK) non-specific Pathogens pathway potential therapeutic target Protective respiratory SARS-CoV-2 SARS-COV-2 infection signaling pathway therapeutic target trained immunity understanding [DOI] 10.3389/fimmu.2022.837524 PMC 바로가기 [Article Type] Immunology
Augmenting existing deterioration indices with chest radiographs to predict clinical deteriorationResearch Article Published on 2022-02-152022-10-28 Journal: PLoS ONE [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] 48 hour Accuracy administration Admission alleviate analyzed AUROC candidate Care Chest Clinical data Clinical deterioration Cohort coronavirus disease COVID-19 defined Deterioration disease models Dyspnea EHR EpiC form fraction Health help hospital Hospital admission Hospitalization hospitalized patient identify Importance IMPROVE in-hospital mortality individual information invasive machine measure mechanical ventilation Model nasal Negative predictive value Non-invasive NPV objective outcome participant Patient patients patients hospitalized patients with COVID-19 predict Result risk tested total patient with COVID-19 [DOI] 10.1371/journal.pone.0263922 PMC 바로가기 [Article Type] Research Article
Influenza A(H1N1)pdm09 Virus but Not Respiratory Syncytial Virus Interferes with SARS-CoV-2 Replication during Sequential Infections in Human Nasal Epithelial CellsArticle Published on 2022-02-152022-10-28 Journal: Viruses [Category] COVID-19, COVID19(2023년), Fulltext, SARS, 신종인플루엔자, [키워드] acute respiratory syndrome alleviate Co-infection combinations coronavirus D614G described evaluated HAE Human Human airway epithelium human nasal epithelium Infection infection with SARS-CoV-2 Influenza Influenza virus inhibitor Interaction interfere interferon involved mechanism mutant nasal other respiratory virus pandemic Post-infection reduce reduced replication Replication replication kinetics respiratory respiratory syncytial virus respiratory viruses RSV RT-qPCR SARS-CoV-2 SARS-CoV-2 replication subsequent viral interference virus [DOI] 10.3390/v14020395 PMC 바로가기 [Article Type] Article
A proficient approach to forecast COVID-19 spread via optimized dynamic machine learning modelsArticle Published on 2022-02-142022-10-04 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] 95% confidence interval addition Algorithm alleviate approach averaged Bayesian Brazil confidence level confirmed COVID-19 case COVID-19 data-driven Decision tree develop feature forest Health care impacted India information investigated machine learning model machine learning models Mathematics and computing predicted provided Result Spread time dependency [DOI] 10.1038/s41598-022-06218-3 PMC 바로가기 [Article Type] Article
A Comprehensive Review of Neuromuscular Manifestations of COVID-19 and Management of Pre-Existing Neuromuscular Disorders in ChildrenReview Published on 2022-02-112022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] alleviate Cardiomyopathy children clinical care Complication Comprehensive COVID-19 COVID-19 pandemic disorder disorders include management manifestation MIS-C muscular muscular dystrophy Neuromuscular Patient patients pediatric Research Restrictive lung disease review risk SARS-CoV-2 scoliosis severe complication spinal muscular atrophy Telemedicine the disease Treatment [DOI] 10.3390/jcm11040934 PMC 바로가기 [Article Type] Review
Risk of Vaccine Breakthrough SARS-CoV-2 Infection and Associated Factors in Healthcare Workers of Trieste Teaching Hospitals (North-Eastern Italy)Article Published on 2022-02-072022-10-28 Journal: Viruses [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] alleviate Analysis Asymptomatic BMI Breakthrough infection category clinical Cohort cohort study Complete COVID-19 COVID-19 patient COVID-19 vaccination Diabetes Mellitus evaluate Factor Gender HCW HCWs Healthcare system healthcare worker Healthcare workers higher risk Infection investigated Italy less male Male sex Mild multivariable logistic regression Nasopharyngeal swab no symptom occupational biological risk occurred pandemic PCR Real-time PCR risk risk factor RT–PCR SARS-CoV-2 SARS-COV-2 infection screened significantly study period Surveillance symptomatic Teaching the disease Trieste univariable vaccination Vaccine worker [DOI] 10.3390/v14020336 PMC 바로가기 [Article Type] Article