Outcomes of treatment of severe COVID-19 pneumonia with tocilizumab: a report of two cases from TunisiaTocilizumab으로 심각한 Covid-19 폐렴의 치료 결과 : 튀니지의 두 가지 사례에 대한 보고서Case Reports Published on 2021-11-022022-09-01 Journal: The Pan African Medical Journal [Category] SARS, 진단, [키워드] “cytokine storm” anti-IL6 Biological biological parameters blocking body weight Case report chest scan clinically correlated COVID-19 COVID-19 infection COVID-19 pathology COVID-19 pneumonia cytokine Cytokine storm decrease Diagnosis Evolution Health Hospitalization hypoxia IL-6 IL6 immune disorders immunomodulatory interleukin interleukin 6 interleukin-6 intravenously morbidity and mortality pandemic parameter Patient Pneumonia regulate SARS CoV SARS CoV-2 Severe case Severe COVID-19 pneumonia significantly Therapeutic approach therapy Tocilizumab tomography Treatment [DOI] 10.11604/pamj.2021.40.126.28020 PMC 바로가기 [Article Type] Case Reports
Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Survey Among 17 971 Healthcare and Administrative Personnel at Hospitals, Prehospital Services, and Specialist Practitioners in the Central Denmark Region중부 덴마크 지역의 병원, 병원 전 서비스 및 전문 개업의의 의료 및 행정 직원 17,971명을 대상으로 한 중증 급성 호흡기 증후군 코로나바이러스 2 혈청 유병률 조사Article Published on 2021-11-022022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, [키워드] 95% confidence interval acute respiratory syndrome Administrative Personnel antibody Beijing Biological China clinics Contact coronavirus coronavirus 2 COVID-19 Denmark enzyme-linked immunosorbent groups healthcare healthcare worker Healthcare workers highest hospitals identify In-hospital lowest participant Patient PCR Pharmacy polymerase chain positive Practitioner Precaution prehospital Prevalence raise Region Regular respiratory SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody testing SARS-CoV-2 RNA Sensitivity and specificity serology seropositive seropositive participants Seroprevalence seroprevalence survey specialist survey tested Transmission [DOI] 10.1093/cid/ciaa1471 PMC 바로가기 [Article Type] Article
COVID-19: Overview of rheumatology fellowsCOVID-19: 류마티스 펠로우 개요Article Published on 2021-11-012022-09-11 Journal: Reumatología clinica [Category] 치료제, [키워드] activity arteritis Arthritis Biological Biological agents Biológicos Case series coronavirus country COVID-19 demonstrated drug drugs English front line giant cell giant cell arteritis health emergency health system immune disorder Infection lack management observational studies observational study off-label Pandemia pandemic para patients randomised clinical trial Randomised clinical trials RCTs resident Residente Resilience Reumatólogos rheumatologist Rheumatologists. rheumatology SARS-COV-2 infection Spanish Spread the disease Therapeutic approach treat Treatment World War World War II Wuhan Wuhan, China [DOI] 10.1016/j.reumae.2020.05.001 PMC 바로가기 [Article Type] Article
Large-Scale Postmarketing Surveillance of Biological Drugs for Immune-Mediated Inflammatory Diseases Through an Italian Distributed Multi-Database Healthcare Network: The VALORE Project이탈리아의 분산 다중 데이터베이스 의료 네트워크를 통한 면역 매개 염증성 질환에 대한 생물학적 약물의 대규모 시판 후 감시: The VALORE 프로젝트Article Published on 2021-11-012022-09-12 Journal: BioDrugs : clinical immunotherapeutics, biopharmac [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome adverse event age Analysis approved association Biological biological drug biological drugs calculated Compound conducted coronavirus cumulative database drug event Follow-up Frequency highest Immune-mediated inflammatory disease incidence rate Inclusion Infection infections inhibitor investigated Italian Italian region Italian regions lowest malignancy management moderate Necrosis offer outcome outcomes Patient power calculation Prevalence provide Region required retrospective cohort study Severe infection Standard deviation Statistical power stratified Surveillance therapeutic TNFα [DOI] 10.1007/s40259-021-00498-3 PMC 바로가기 [Article Type] Article
Linarin, a Glycosylated Flavonoid, with Potential Therapeutic Attributes: A Comprehensive ReviewReview Published on 2021-10-292022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] acetylcholinesterase activity assessment bioactivities Biological biological properties Buddleja Central nervous system Characteristics characterized chemotaxonomy Cirsium CNS compounds Comprehensive derivatives dietary supplement disorders drug candidates Effect exhibited flavonoid flavonoids Health indicated inhibitory activity linarin Osteoarthritis Osteoporosis pharmacological phytochemistry Potential proliferation review therapeutic [DOI] 10.3390/ph14111104 PMC 바로가기 [Article Type] Review
Laboratory diagnosis and management of COVID-19 cases: creating a safe testing environmentResearch Article Published on 2021-10-292022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] analyzed association Awareness Biological biosafety Cabinet Community COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 pandemic creating demonstrated effort enabling factor ENhance equipment Factors IBM Infection influence initiation of treatment Laboratory laboratory diagnosis Laboratory environment Laboratory safety Laboratory testing Laboratory-testing majority management measure Measures Medical scientist Nigeria Personal efforts positive PPE questionnaire required Result risk Safe Safety Safety enabling factors significantly SPSS Statistics study participant supplementary material Support Wuhan, China [DOI] 10.1186/s12879-021-06806-0 PMC 바로가기 [Article Type] Research Article
Assessing the Role of Trust in Information Sources, Adoption of Preventive Practices, Volunteering and Degree of Training on Biological Risk Prevention, on Perceived Risk of Infection and Usage of Personal Protective Equipment Among Italian Medical Students During the SARS-CoV-2 PandemicPublic Health Published on 2021-10-282022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] activities adopted adoption Affect Analysis Assessing average benefit Biological Characteristics COVID COVID-19 COVID-19 pandemic cross-sectional daily living degree Effect exogenous factor healthcare Healthcare system help highest hospital Implementing Infection Infectious disease influence information initial Intervention Italian knowledge lack medical student mitigate pandemic Perceived Perceived risk Poisson regression model PPE prevention preventive measure preventive measures public health risk risk of infection Risk perception role SARS-CoV-2 School Seven source of information student survey the SARS-CoV-2 training Trust University of Bologna Usage viral infection voluntary voluntary service volunteering [DOI] 10.3389/fpubh.2021.746387 PMC 바로가기 [Article Type] Public Health
Biological and Clinical Significance of Adaptive Evolution of CoronavirusesEditorial Published on 2021-10-232022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] Biological clinical Significance [DOI] 10.3390/life11111129 PMC 바로가기 [Article Type] Editorial
Biological Significance of the Genomic Variation and Structural Dynamics of SARS-CoV-2 B.1.617Microbiology Published on 2021-10-072022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute respiratory syndrome amino acid change analyzed B.1.617 B.1.617.2 binding ability Biological biological significance circulating coronavirus country COVID-19 pandemic Deletion Dynamics Follow-up Frequency genetic diversity Genome genomic variation Haplotype Haplotype network increasingly India indicated involved L452R lifted Lineage measure molecular evolution mutant Mutation N501Y nonstructural proteins P681R pandemic Positive selection predominant prevalent reported SARS-CoV-2 sequence sequenced Significance Single nucleotide polymorphism SNPs Spread Structural analysis structural proteins Substitution tertiary structure the S protein the vaccine tracing variant viral genome [DOI] 10.3389/fmicb.2021.750725 PMC 바로가기 [Article Type] Microbiology
Biological Risk in Italian Prisons: From the COVID-19 Management to the Development of a Standardized Model for Emergency ResponseArticle Published on 2021-10-012022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] addition administration adopted approved Biological biological risk communicable diseases contagious contingency plan COVID-19 COVID-19 outbreak COVID-19 pandemic Critical Deceased development disease draft Emergency Epidemics epidemiological feature General population handling Health highlight indoor facilities information International Italian Local measure Model National National Health Service Outbreaks prison prison system public health recommendation resource respond response service sick summer WHO’ [DOI] 10.3390/ijerph181910353 PMC 바로가기 [Article Type] Article