An observational, cohort, multi-centre, open label phase IV extension study comparing preschool DTAP-IPV booster vaccine responses in children whose mothers were randomised to one of two pertussis-containing vaccines or received no pertussis-containing vaccine in pregnancy in England영국에서 임신 중 두 가지 백일해 포함 백신 중 하나에 무작위로 배정된 어머니를 둔 어린이와 백일해 포함 백신을 받지 않은 어린이의 유아 DTAP-IPV 부스터 백신 반응을 비교하는 관찰적 코호트 다기관 개방 라벨 4상 확장 연구Article Published on 2022-11-222024-08-19 Journal: Vaccine [Category] 백일해, 파상풍, 폴리오, [키워드] blunting booster children immune immunisation maternal vaccination pertussis Pregnancy response Vaccine [DOI] 10.1016/j.vaccine.2022.10.005
A booster hepatitis B vaccine for children with maternal HBsAg positivity before 2 years of age could effectively prevent vaccine breakthrough infectionsArticle Published on 2022-11-182023-06-12 Journal: BMC Infectious Diseases [Category] B형 간염, [키워드] booster Long-term protective effect Mothers with chronic HBV infection vaccine breakthrough infections Yeast recombinant hepatitis B vaccine. [DOI] 10.1186/s12879-022-07854-w PMC 바로가기
Protection against Omicron from Vaccination and Previous Infection in a Prison SystemArticle Published on 2022-11-102022-11-16 Journal: The New England Journal of Medicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Analysis B.1.1.529 B.1.617.2 booster collected Combination coronavirus Cox model dose doses effective Effectiveness estimate evaluate evaluated hazard ratio high-risk population Infection mRNA mRNA vaccination mRNA vaccine offered omicron Omicron variant prison protection ranged retrospective cohort risk of infection SARS-CoV-2 significantly more stratified System vaccination vaccine dose vaccine doses variant were used [DOI] 10.1056/NEJMoa2207082 PMC 바로가기
Evaluation of commercially available fully automated and ELISA-based assays for detecting anti-SARS-CoV-2 neutralizing antibodiesArticle Published on 2022-11-082022-11-15 Journal: Scientific Reports [Category] SARS, 치료기술, [키워드] acute respiratory syndrome administration affecting Analysis anti-RBD IgG antibody anti-SARS-CoV-2 AUC automated binding antibody booster clinical settings Cohort collected Control coronavirus correlation COVID-19 cutoff value demonstrated Effectiveness Genscript gold standard Immunity immunoassay in both groups infected patient Mindray NAb neutralization Neutralization assay neutralization test neutralizing antibody population level protective immunity provide pseudovirus R 2 Rapid receiver operating characteristic Research ROC ROC Curve Sample SARS-CoV-2 SARS-CoV-2 infected patient second dose sensitivity shown significantly specificity subjects sVNT sVNT assay symptoms onset tested threshold vaccinated individual Vaccine virus neutralization test was performed [DOI] 10.1038/s41598-022-21317-x PMC 바로가기
Viral load dynamics of SARS-CoV-2 Delta and Omicron variants following multiple vaccine doses and previous infectionArticle Published on 2022-11-072022-11-16 Journal: Nature Communications [Category] SARS, 변종, [키워드] affected affecting booster can be used COVID-19 cycle threshold Delta Delta wave demonstrated effective Effectiveness implication individuals Infection Laboratory less morbidity and mortality natural infection omicron pathogen public health qRT-PCR reduce SARS-CoV-2 significantly sustained the vaccine Transmissibility vaccination Vaccine vaccine dose variant Viral load while [DOI] 10.1038/s41467-022-33096-0 PMC 바로가기
An additional dose of viral vector COVID-19 vaccine and mRNA COVID-19 vaccine in kidney transplant recipients: A randomized controlled trial (CVIM 4 study)Article Published on 2022-11-012022-11-15 Journal: American journal of transplantation : official jou [Category] COVID19(2023년), SARS, 진단, [키워드] age anti-RBD antibody B cell response BNT162b2 booster Cell-mediated immunity ChAdOx1 ChAdOx1 nCoV-19 comparable Coronavirus disease 2019 COVID-19 COVID-19 vaccine dose elicit group humoral immunization Immunocompromised immunogenicity investigated IQR kidney transplant male median mononuclear cells mRNA mRNA-1273 no difference participant Peripheral blood positive Randomized Randomized controlled trial receive recipients response SARS-CoV-2 seroconversion rate significantly statistically T cell Vaccine Viral vector virus neutralization test [DOI] 10.1111/ajt.17151 PMC 바로가기
Immunogenicity and safety of SpikoGen®, an adjuvanted recombinant SARS-CoV-2 spike protein vaccine as a homologous and heterologous booster vaccination: A randomized placebo-controlled trialArticle Published on 2022-11-012022-11-15 Journal: Immunology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% confidence interval Administered adverse event approved assessment booster booster dose booster vaccination clinical trials Course COVID-19 COVID-19 vaccination COVID-19 vaccine cross-neutralization cross-neutralization. Day double-blind Effect fatigue Heterologous homologous humoral immunogenic immunogenicity incidence injection site pain Local Neutralizing antibodies neutralizing antibody outcome participant Participants Placebo placebo-controlled primary immunogenicity Randomized randomized placebo-controlled trial Recombinant spike protein reported robust Safe Safety safety profile saline placebo SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variants Serious Adverse Event Serious Adverse Events Seroconversion seroconversion rate shown SpikoGen subunit the placebo group Trial Vaccine was performed [DOI] 10.1111/imm.13540 PMC 바로가기
Effectiveness of Second mRNA COVID-19 Booster Vaccine in Immunocompromised Persons and Long-Term Care Facility ResidentsArticle Published on 2022-11-012023-07-10 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), [키워드] booster coronavirus disease COVID-19 mRNA respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 South Korea Vaccine viruses zoonoses [DOI] 10.3201/eid2811.220918 PMC 바로가기
Pronounced antibody elevation after SARS-CoV-2 BNT162b2 mRNA booster vaccination in nursing home residentsArticle Published on 2022-11-012022-11-15 Journal: Influenza and Other Respiratory Viruses [Category] SARS, 진단, [키워드] age Anti-spike antibody Antibody Response BNT162b2 mRNA vaccination booster booster dose booster vaccination changed characterized COVID-19 COVID-19 outbreak Critical domain dose evaluated Factor four groups groups healthcare healthcare worker highest IgG infected individual initial lowest median mRNA nursing home residents public health RBD Responder SARS-CoV-2 SARS-CoV-2 BNT162b2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine second dose significantly higher vaccination [DOI] 10.1111/irv.13030 PMC 바로가기
Antibody and T-cellular response to COVID-19 booster vaccine in SARS-CoV-1 survivorsSARS-CoV-1 생존자의 COVID-19 추가 백신에 대한 항체 및 T세포 반응Article Published on 2022-11-012022-11-15 Journal: Clinical immunology (Orlando, Fla.) [Category] SARS, 백일해, 진단, 파상풍, [키워드] acute respiratory syndrome Antibody titer Beta booster booster vaccination Booster vaccine CD4 CD8 comparable coronavirus COVID-19 Delta dose effective elicit elicited generate healthy individual humoral immune response less MOST naïve neutralization neutralizing antibody omicron robust SARS-CoV-1 SARS-CoV-1 survivors SARS-CoV-2 survivor Survivors T cell response T cell responses T-cell Response WA1 while Wuhan-Hu-1 [DOI] 10.1016/j.clim.2022.109103 PMC 바로가기