Candida – Page 7 – Communicable Diseases Research

Exposure of Candida albicans β (1,3)-glucan is promoted by activation of the Cek1 pathway

Cek1 경로의 활성화에 의해 칸디다 알비칸스 β(1,3)-글루칸의 노출이 촉진됩니다

Research Article

Published on 2019-01-312022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

Functional diversification accompanies gene family expansion of MED2 homologs in Candida albicans

기능적 다양화는 칸디다 알비칸스에서 MED2 상동체의 유전자 패밀리 확장을 수반합니다

Research Article

Published on 2018-04-092022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] 3’ end accompany addressed affected aggregation biological function Biological functions buffer Candida Candida albican Candida albicans Cell Combination commensal complex component conserved contribute contributed correlated did not produce difficulty domain duplication Effect entire gene example expansion expression facilitate family members function functional functions Gene duplication gene families gene family generate Genes genetic diversity greater growth homolog identify INDEL individual gene individual genes induced Infection influence involved killing Macrophage mapped mechanism mediator Mutation natural selection neofunctionalization occurred opportunistic pathogen organism overlap pathogen pathogenic phenotype Phenotypes phenotypic phenotypic effect polymorphic site Positive selection promoter provide question regulate regulated Regulation Regulatory repeated selective pressure sequence sequence similarity Specific strain Strains subfunctionalization subunit sucrose traits transcriptional transcriptional regulator unique Variability variant virulence were assessed yeast
[DOI] 10.1371/journal.pgen.1007326 PMC 바로가기 [Article Type] Research Article

Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans

Wor1은 Candida albicans에서 일반적인 공동 억제 인자 Tup1의 억제를 통해 불투명한 세포 운명을 설정합니다.

Research Article

Published on 2018-01-162022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] absence Affect Affinity purification analyses analysis approach Author bypass Candida Candida albican Candida albicans carbon carbon source carbon sources Cell cell fate cells colonization colonize commensal complex protein explain expressed facilitate Factor function functions fungal Genetic gut microbiota Host identify individuals induce Loss maintain mass spectrometry mass spectroscopy master regulator mechanism molecular Morphological occur pathogen pathogenic phenotypic plasticity positive feedback promoter Proteins provide Region regulated Regulation regulatory circuit repression repressor serious infection serious infections stability starting switching temperature transcriptional transcriptional repressor undergo white Wor1
[DOI] 10.1371/journal.pgen.1007176 PMC 바로가기 [Article Type] Research Article

Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1

단백질 키나제 Cak1의 발현 감소를 통한 칸디다 알비칸스 필라멘트/생물막 조절기 우회

Research Article

Published on 2016-12-092022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] absence activating Activation antimicrobial Antimicrobials bacterial pathogen biofilm bypass Candida Candida albican Candida albicans Cell cell cycle cell growth cell proliferation contribute coupling dependence determinant diminished Effectiveness Express expresse expression Filamentous functional Gene Expression Genes growth implicated induce Infection infections information inhibition invasive kinase leads Medical devices Mutation occur organism pathogen Pathogens proliferation property Protein protein kinase reduced regulator Regulatory required Screen Stimulation strain Strains Target genes the cell transcription factor transcription factors wild-type
[DOI] 10.1371/journal.pgen.1006487 PMC 바로가기 [Article Type] Research Article

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues

Lrg1, Rho1 및 Pkc1을 통한 신호는 다양한 신호에 대한 응답으로 Candida albicans 형태 형성을 제어합니다

Research Article

Published on 2016-10-272022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] absence Activation adenylyl cyclase allele analysis blocked CAMP Candida Candida albican Candida albicans canonical cascade Cell cell growth concert Critical defined Deletion developmental disease downstream example form function functional fungal fungal pathogens Genetic growth GTPase healthy homozygous hosts Human humans hyphal identify Immunocompromised implicated inactive independent independent of Infection insertion invasive leads Lrg1 morphogenesis Morphological morphology mutant Mutation not impaired pathogen Pathogenesis Pathogens pathway positive promoted reduced regulate represse repression required response screened serum signaling pathway skin infections strain Strains transition transposon virulence yeast
[DOI] 10.1371/journal.pgen.1006405 PMC 바로가기 [Article Type] Research Article

Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp .

TLO 중재자 소단위 유전자의 증폭은 칸디다 종에서 필라멘트 성장을 촉진합니다.

Research Article

Published on 2016-10-142022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] Activation amplification amplitude ascomycete ascomycetes binding domain bloodstream infection Bloodstream infections Candida Candida albican Candida albicans candidiasis cause cell physiology complex death DNA domain Engineering ENhance environmental cues eukaryotic exhibit facilitated Filamentous fungal fungi gene family Genome genomes genomic growth hallmark individual Infection infections Interaction less mediator mortality rate multitude murine mutant Nuclear localization nuclear localization signal nucleus ortholog overexpressed overexpression pathogenicity phenotype Phenotypes phenotypic plasticity Protein provide reduced regulate subunit Support systemic Candidiasis systemic infection target targets The United States Transcription transcription factor transcription factors transcriptional transcriptional activation unique United States virulence
[DOI] 10.1371/journal.pgen.1006373 PMC 바로가기 [Article Type] Research Article

Neocentromeres Provide Chromosome Segregation Accuracy and Centromere Clustering to Multiple Loci along a Candida albicans Chromosome

네오센트로미어는 칸디다 알비칸스 염색체를 따라 여러 유전자좌에 염색체 분리 정확도 및 중심체 클러스터링을 제공합니다

Research Article

Published on 2016-09-232022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] Accuracy adaptation addition approach assembly benefit Cancer cancer cell Cancer cells cancers Candida Candida albican Candida albicans caused Cell cell division centromere change Chemotherapy chromosome chromosome 5 chromosome segregation chromosomes Cluster Clustering Complexes consequence Contact copy number de novo defined disease DNA DNA sequence drug resistance error rate exhibit function functional functions Gene Expression Genes Genome greater independent independent of instance kinetochore leads Like loci maintain mechanisms Multiple nuclear nucleus observation occur organism protein complex Proteins provide recent reduced Region reorganization required segregation speciation stability Support the cells three-dimensional structure Transcription yeast
[DOI] 10.1371/journal.pgen.1006317 PMC 바로가기 [Article Type] Research Article

Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant

대식세포에서 칸디다 알비칸스의 소진화는 필라멘트가 아닌 돌연변이에서 필라멘트를 복원합니다

Research Article

Published on 2014-12-042022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] addition Antifungal treatment approach avirulent C. albican C. albicans Candida Candida albican Candida albicans Cdk8 Cell cell wall clinical setting complex component Compound connection drug resistance ENCODE environmental cue environmental cues Evolution example exhibited fungi gene encoding growth hosts hyphae hyphal identify in vivo Incubation induce Infection leads Macrophage macrophages maintain mechanism mediator Mediator complex microbe microevolution microevolutionary microorganism microorganisms Missense mutation murine mutant Mutation nucleotide pathogenic pathogenicity phagocytosis regulatory network responsible selection pressure Signaling signaling pathway single nucleotide strain subject the macrophage phagosome These data took place Transcription transcription factor transcription factors transcription regulation transcriptional transcriptional regulation undergo virulence whole genome yeast
[DOI] 10.1371/journal.pgen.1004824 PMC 바로가기 [Article Type] Research Article