Effects of surgical and FFP2 masks on cardiopulmonary exercise capacity in patients with heart failureRandomized Controlled Trial Published on 2022-08-232022-10-05 Journal: PLoS ONE [Category] SARS, 임상, [키워드] activity Adults age Cardiopulmonary changed chronic heart failure clinically cross-over discomfort Effect Ejection fraction Exercise capacity facemask healthy heart failure LVEF Mask maximum oxygen uptake Patient patients peak ventilation quantified questionnaire Randomized reduce reduction in sequence significantly significantly increased surgical transmission of SARS-CoV-2 ventricular was reduced [DOI] 10.1371/journal.pone.0269470 PMC 바로가기 [Article Type] Randomized Controlled Trial
SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy Research Published on 2022-08-192022-10-05 Journal: Pediatric Research [Category] SARS, 치료기술, 치료법, [키워드] Autoimmune clinical implications clinically cohort study COVID-19 death elevated elicited evaluated fetal gastrointestinal tract gestation Gut Health hospital IFN-γ IL-6 immune Impact in utero Infant Inflammatory Inflammatory cytokine interferon-γ interleukin-6 intestinal intestine investigated Liver disease macrophages mechanism Microbiome MOST mother nasal Neonatal Newborn PCR Pregnancy Protein required resolved Result risk SARS Coronavirus SARS CoV-2 SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission spike Stool swabs Transmission transmission of SARS-CoV-2 Viral reservoir Viral RNA with COVID-19 [DOI] 10.1038/s41390-022-02266-7 [Article Type] Research
SARS-CoV-2 antibodies and breakthrough infections in the Virus Watch cohortVirus Watch 코호트의 SARS-CoV-2 항체 및 획기적인 감염Article Published on 2022-08-182022-09-12 Journal: Nature Communications [Category] SARS, 진단, [키워드] 95% confidence interval anti-S anti-S antibody antibody BNT162b2 booster vaccination Breakthrough infection ChAdOx1 clinically Cohort Course Delta Effectiveness Efficacy Evidence geometric hazard higher risk Increasing individual Infection nine Older protective effect provide Ratio reduced risk risk risk of infection SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 vaccine second dose Support the timing total effect Vaccine [DOI] 10.1038/s41467-022-32265-5 PMC 바로가기 [Article Type] Article
COVID-19 Self-Test Data: Challenges and Opportunities – United States, October 31, 2021-June 11, 2022COVID-19 자가 테스트 데이터: 도전과 기회 - 미국, 2021년 10월 31일-2022년 6월 11일Article Published on 2022-08-122022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 치료기술, [키워드] addition agency Care care provider cause CDC challenge clinically Combination Completeness contributed COVID-19 COVID-19 case COVID-19 tests Demographic variables detect Health Health care IMPROVE include Increased indicated infection with SARS-CoV-2 information Infrastructure opportunity performed point-of-care point-of-care test point-of-care tests positive public health public health authorities public health authority receive reduce reported Reporting risk reduction Supply chain Surveillance Treatment United States virus Volume website [DOI] 10.15585/mmwr.mm7132a1 PMC 바로가기 [Article Type] Article
Developing a Long COVID Phenotype for Postacute COVID-19 in a National Primary Care Sentinel Cohort: Observational Retrospective Database AnalysisObservational Study Published on 2022-08-112022-10-04 Journal: JMIR Public Health and Surveillance [Category] 임상, [키워드] 95% CI acute COVID-19 acute infection addition biomedical ontologies BioPortal Clinical characteristics clinical symptom clinically coded coding college Comorbidities complex computerized contribute COVID COVID-19 data accuracy data extracts data sets database develop Developing diagnosed Diagnosis Digital tool disease disease management Electronic health record English Epidemiology Ethnicity general practitioner General practitioners groups had no Health Hospital admission Hospitalization Hospitalized include individual Infection Laboratory Logistic regression Long Long COVID long-COVID management medical record systems nomenclature office ontological Ontology Oxford Patient phenotype postacute COVID-19 syndrome primary care problems public health RCGP recorded recruited Research retrospective RSC SARS-CoV-2 sentinel social class Sociodemographic Study protocol Surveillance Symptom Systematized Nomenclature of Medicine used data Validity [DOI] 10.2196/36989 PMC 바로가기 [Article Type] Observational Study
Effect of interleukin-6 receptor antagonists in critically ill adult patients with COVID-19 pneumonia: two randomised controlled trials of the CORIMUNO-19 Collaborative GroupCOVID-19 폐렴이 있는 위독한 성인 환자에서 인터루킨-6 수용체 길항제의 효과: CORIMUNO-19 공동 그룹의 2건의 무작위 대조 시험Article Published on 2022-08-102022-09-11 Journal: The European Respiratory Journal [Category] Fulltext, SARS, 임상, [키워드] 95% CI antagonist anti-IL-6 receptor assigned Bayesian clinical trials clinically controlled clinical trials coronavirus disease Coronavirus disease 2019 COVID-19 credible interval CrI Critically ill Critically ill patient critically ill patients determine Effect events group hazard ratio IMPROVE indicated interleukin-6 receptor intravenously investigator-initiated mechanical ventilation median multicentre NIV Noninvasive ventilation not need numbers of patient Open-label outcome Patient patients with COVID-19 Pneumonia posterior probability randomised randomised controlled randomised controlled trial Randomly receive receptor risk of death SARI sarilumab significantly TCZ TOCI Tocilizumab Trial usual care with COVID-19 [DOI] 10.1183/13993003.02523-2021 PMC 바로가기 [Article Type] Article
A CRISPR-based ultrasensitive assay detects attomolar concentrations of SARS-CoV-2 antibodies in clinical samplesCRISPR 기반 초고감도 분석은 임상 샘플에서 SARS-CoV-2 항체의 원자 농도를 감지합니다.Article Published on 2022-08-092022-09-11 Journal: Nature Communications [Category] SARS, 바이오마커, 진단, 치료기술, [키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Antibody detection classic clinical clinical sample clinical samples Clinical use clinically collected Concentration CRISPR detect diagnostics General population homogeneous immunoassay immunoassays kidney transplant recipient Laboratory large cohort nucleic acid Nucleic acid detection nucleic acids point-of-care powerful tool Proteins Quantitative analysis SARS-CoV-2 antibody sensitivity serum serum sample serum samples shown simplicity specificity translate [DOI] 10.1038/s41467-022-32371-4 PMC 바로가기 [Article Type] Article
Convalescent plasma therapy for patients with severe COVID-19: A case series study중증 COVID-19 환자를 위한 회복기 혈장 요법: 사례 시리즈 연구Case Reports Published on 2022-08-052022-09-11 Journal: Medicine [Category] SARS, 치료제, [키워드] Administered allergic allergic reaction alleviation alleviation of symptoms analyzed antiviral drug antiviral drugs arterial oxygen saturation bilateral lungs C-reactive protein case sery CD3+ CD4 CD8+ cerebral infarction Chest computed tomography Clinical data clinically collected Computed tomography convalescent plasma coronavirus disease Coronavirus disease 2019 cough COVID-19 CP infusion diabetes dysfunction early treatment effective Efficacy and safety elevated exhibited female Fever hospital hypertension IMPROVE Infarction interleukin interleukin-6 investigated lack lesion lesions lymphocyte Lymphocytes male Mild multiple-organ oxygen oxygen saturation Patient patients plasma postoperative respiratory infectious disease Safe severe adverse reaction severe adverse reactions severe COVID-19 severe disease Shortness of breath subset Supportive treatments Symptom T lymphocyte T lymphocytes the patient therapeutic therapy Thyroid Thyroid adenoma treated Treatment underlying disease [DOI] 10.1097/MD.0000000000029912 PMC 바로가기 [Article Type] Case Reports
Humoral responses to the SARS-CoV-2 spike and receptor binding domain in context of pre-existing immunity confer broad sarbecovirus neutralization기존 면역의 맥락에서 SARS-CoV-2 스파이크 및 수용체 결합 도메인에 대한 체액 반응은 광범위한 사베코바이러스 중화를 부여합니다Article Published on 2022-08-042022-09-12 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] approved B cell response Candidates clinically coronavirus elicited Epitopes evaluated Evaluating Humoral response IgG immune immune imprinting immune response immunization Infection naïve neutralization pre-existing immunity RBD reactivity Receptor binding domain receptor binding domain (RBD) regimen sarbecovirus Sarbecoviruses SARS-CoV-2 serum spike (S). spike glycoprotein the SARS-CoV-2 vaccination vaccine candidate [DOI] 10.3389/fimmu.2022.902260 PMC 바로가기 [Article Type] Article
The Effectiveness of a Four-Week Digital Physiotherapy Intervention to Improve Functional Capacity and Adherence to Intervention in Patients with Long COVID-19Clinical Trial Published on 2022-08-032022-10-04 Journal: International Journal of Environmental Research an [Category] SARS, 임상, [키워드] adherence Capacity carried clinically complementary COVID-19 defined diagnosed Diagnosis Digital digital physiotherapy practice effect size feasible functional functional capacity identify individual Intervention Long Long COVID-19 maintain medium Participants Patient Physiotherapy randomised clinical trial Research Safe SARS-COV-2 infection statistically significant STS subject Symptom telerehabilitation the disease therapeutic therapeutic adherence Treatment [DOI] 10.3390/ijerph19159566 PMC 바로가기 [Article Type] Clinical Trial