Clinical evaluation of Sofia Rapid Antigen Assay for detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among emergency department to hospital admissions응급실부터 입원까지 중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 검출을 위한 Sofia Rapid Antigen Assay의 임상적 평가Article Published on 2022-08-012022-09-11 Journal: Infection Control and Hospital Epidemiology [Category] SARS, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Admission Analysis Antigen Asymptomatic calculated Characteristics clinical Clinical characteristics clinical utility Community conducted coronavirus cross-sectional analysis cycle threshold determine emergency department evaluated false-negative fluorescent hospital Hospital admission immunoassay initial Negative predictive value no difference no differences Patient patients PCR assays positive predictive values Quality improvement Rapid replacement RT-PCR RT-PCR Ct SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 RT-PCR sensitivity specificity Symptom symptomatic and asymptomatic symptomatic and asymptomatic patients symptomatic individuals Transmission turnaround time utility [DOI] 10.1017/ice.2021.281 PMC 바로가기 [Article Type] Article
Variant-specific SARS-CoV-2 within-host kinetics변이체 특이적 SARS-CoV-2 숙주 내 역학Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] alpha and delta variants Alpha variant Analysis caused Chain Reaction characterized Cohort contagiousness copy number Ct values cycle threshold ddPCR Delta determinant digital PCR Epidemic epidemiological Evidence France General population highlight hospital individual Infection Kinetics lineages no significant difference Older performed polymerase chain polymerase chain reaction populations Quantitative RT-qPCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV2 screening test significant difference significantly higher Swab translate Transmission upper respiratory tract variant variant of concern variants variations viral dynamics viral genome virus virus load VoC VOCs within-host [DOI] 10.1002/jmv.27757 PMC 바로가기 [Article Type] Article
Factors associated with weak positive SARS-CoV-2 diagnosis by reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR)Article Published on 2022-08-012023-07-09 Journal: Pathology [Category] COVID19(2023년), [키워드] biological sampling cycle threshold RT-qPCR SARS-CoV-2 diagnosis [DOI] 10.1016/j.pathol.2022.04.001 PMC 바로가기
Elucidation of correlation between SARS-CoV-2 RdRp and N gene cycle threshold (Ct) by RT-PCR with age and gender연령 및 성별에 따른 RT-PCR에 의한 SARS-CoV-2 RdRp와 N 유전자 주기 역치(Ct) 간의 상관관계 규명Article Published on 2022-08-012022-09-11 Journal: Clinica chimica acta; international journal of cli [Category] COVID19(2023년), SARS, 치료법, [키워드] Abu acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age age and gender Analysis association caused children conducted coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patients COVID19 Ct value Ct values cycle cycle threshold Diseases dynamic Factor female females Gender global public health global public health emergency implication in viral individual longitudinal longitudinal analysis male mutated N gene N genes no statistically significant difference outcome P-value prevalent ranged RdRP RdRp gene risk rRT-PCR RT-PCR SARS-CoV-2 SARS-CoV-2 RdRp second wave significantly higher statistically significant difference strain study period target threshold Viral load viral loads [DOI] 10.1016/j.cca.2022.06.008 PMC 바로가기 [Article Type] Article
Cycle threshold responses in SARS-COV2 PCR tests depend on the method by which the samples were obtained and require strict global standardizationSARS-COV2 PCR 테스트의 주기 임계값 응답은 샘플을 얻은 방법에 따라 다르며 엄격한 글로벌 표준화가 필요합니다.Article Published on 2022-08-012022-09-11 Journal: Infection [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis CDC Ct values cycle cycle threshold detect determine emergency room Epidemic false negatives hospitals include PCR PCR test penetration platform reduce response risk SARS-CoV2 Schools Standardization Swab threshold Viral load virus [DOI] 10.1007/s15010-022-01772-4 PMC 바로가기 [Article Type] Article
Accuracy of 2 Rapid Antigen Tests During 3 Phases of SARS-CoV-2 VariantsArticle Published on 2022-08-012022-11-15 Journal: JAMA Network Open [Category] SARS, 변종, 치료기술, [키워드] 95% CI Accuracy age Alter Antigen B.1.617.2 Card clinical testing collected COVID-19 COVID-19 testing COVID-19 vaccination Culture cycle threshold Delta demonstrated diagnostic diagnostic sensitivity diagnostic tests enrolled female infectious dose Intervention IQR King limit of detection median nasal swab no significant difference nucleocapsid antigen Older omicron outcome participant phase positive ranged Rapid rapid antigen test Rapid diagnostic test reduce reported RT-PCR RT-PCR testing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission SARS-CoV-2 variants sequence variation specificity specimen Symptom symptom onset Test tested The diagnostic sensitivity tissue USA-WA1/2020 variant variants viral genome Viral load Washington wild-type with COVID-19 [DOI] 10.1001/jamanetworkopen.2022.28143 PMC 바로가기
Environmental SARS-CoV-2 contamination in hospital rooms of patients with acute COVID-19급성 COVID-19 환자의 병실 환경 SARS-CoV-2 오염Article Published on 2022-08-012022-09-11 Journal: The Journal of hospital infection [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% confidence interval acute COVID-19 acute phase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Airborne contamination Analysis Chain Reaction consecutive patient Contamination coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 Culture cycle threshold environmental contamination evaluate Face mask Factor Frequency HCW healthcare worker Healthcare workers higher risk hospital identify infection control Infectious virus Isolation marker Mask Masks Odds ratio Patient polymerase chain polymerase chain reaction positive result positive sample qPCR Quantitative reverse transcription risk RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA Seven Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly the disease the patient Transmission Vero Cell Vero cells Viral isolation virus was performed [DOI] 10.1016/j.jhin.2022.05.003 PMC 바로가기 [Article Type] Article
Whole blood samples for faster real-time PCR analysis of thrombophilic mutations in SARS-CoV-2 virus positive patientsArticle Published on 2022-07-292022-11-16 Journal: Physiological research [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis Blood blood sample carried carrier carriers Complete Concordance COVID-19 COVID-19 positive patients cycle threshold demonstrated DNA DNA extraction DNA molecule evaluated faster genotyping healthy heterozygote heterozygous homozygote homozygous incidence Laboratory Leiden median Modification Mutation mutations outpatients patients with COVID-19 PCR performed positive positive patient protocol provided real time Real-time PCR reported SARS-CoV-2 virus significant difference significantly subject thawing thrombosis Venous Thromboembolism Whole blood whole blood sample [DOI] 10.33549/physiolres.934883 PMC 바로가기
Multiplex Fragment Analysis for Flexible Detection of All SARS-CoV-2 Variants of Concern우려되는 모든 SARS-CoV-2 변이체의 유연한 검출을 위한 다중 단편 분석Article Published on 2022-07-272022-09-11 Journal: Clinical Chemistry [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] ABI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus allele Analysis analyzed approach capillary electrophoresis concern coronavirus cycle threshold deleted Deletion Delta detection effective equipment exhibited fluorescent fragment insertion insertions Lambda limit of detection multiplex mutants omicron ORF1a ORF8 PCR performed primer primer pair primer pairs RDR RDR1 RDR2 RDR3 Receptor binding domain resolved respiratory specimens S-gene SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sensitivity Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specificity subsequent target variant variants variants of concern VoC VOCs WGS whole genome Whole genome sequencing [DOI] 10.1093/clinchem/hvac081 PMC 바로가기 [Article Type] Article
The importance of effect sizes when comparing cycle threshold values of SARS-CoV-2 variantsSARS-CoV-2 변이체의 주기 임계값을 비교할 때 효과 크기의 중요성Article Published on 2022-07-212022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] age Alpha variant Alpha VOC Analysis ANOVA Beta calculation carried clinical setting Combination Ct values cycle threshold Cycle threshold value effect size effect sizes estimate Gender group investigated magnitude marker mechanism mutations Occurrence onset of symptoms outpatients P-value p-values Patient positive sample post-hoc Retrospective study SARS-CoV-2 SARS-CoV-2 variant significant effect significantly statistical analysis study period Transmission variants of SARS-CoV-2 Viral load viral variant VoC were recorded wild type [DOI] 10.1371/journal.pone.0271808 PMC 바로가기 [Article Type] Article