Coronavirus disease 2019 and the gut–lung axisPerspective Published on 2021-09-102023-07-01 Journal: International Journal of Infectious Diseases [Category] SARS, [키워드] Coronavirus disease 2019 Dysbiosis gut–lung axis Immunity microbiota [DOI] 10.1016/j.ijid.2021.09.013 PMC 바로가기 [Article Type] Perspective
Progressive deterioration of the upper respiratory tract and the gut microbiomes in children during the early infection stages of COVID-19Research article Published on 2021-09-012022-10-05 Journal: Journal of genetics and genomics = Yi chuan xue ba [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome affected Alter children clinical recovery Complication coronavirus coronavirus disease Course COVID-19 Deterioration discharge Disturbed Dysbiosis early infection evaluated Gut gut microbiota Health hospital individuals Infection less longitudinal manifested mechanism Microbiome morbidity and mortality nine persist predisposition Progressive Pseudomonas risk SARS-CoV-2 SARS-CoV-2/COVID-19 Stage susceptible upper respiratory Upper respiratory microbiome upper respiratory tract [DOI] 10.1016/j.jgg.2021.05.004 [Article Type] Research article
The human symbiont Mucispirillum schaedleri: causality in health and diseasearticle Published on 2021-08-312024-09-01 Journal: Medical Microbiology and Immunology [Category] 살모넬라증, [키워드] Colitogenic Crohn’s disease Dysbiosis Inflammation Microbiome Pathobiont ulcerative colitis [Article Type] article
Gut Microbiota Dysbiosis Is a Crucial Player for the Poor Outcomes for COVID-19 in Elderly, Diabetic and Hypertensive PatientsMedicine Published on 2021-08-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome aging Bacteria Bacterial bloodstream caused circulating Comorbidity coronavirus correlation COVID-19 COVID-19-related death COVID19 Cytokines death diabetes Diabetic Dysbiosis elderly group Gut gut microbiota hypertension hypertensive IL-6 immune increase in infected with SARS-CoV-2 Infectious disease Inflammatory intestinal permeability LPS modulation outcome pandemic Patient Poor pro-inflammatory proportion risk SARS-CoV-2 systemic inflammation the cytokine storm the disease therapeutic strategy translocation weakness [DOI] 10.3389/fmed.2021.644751 PMC 바로가기 [Article Type] Medicine
Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients감염 초기에 높은 바이러스 부하에 의한 인터페론 반응 유도는 COVID-19 환자의 심각한 결과로부터 보호할 수 있습니다Article Published on 2021-08-032022-09-10 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, 치료기술, [키워드] Analysis antiviral response antiviral responses cellular Clinical outcome clinical outcomes Co-infection Cohort component correlated COVID-19 COVID-19 patient COVID-19 patients Critical defined disease severity Dysbiosis early phase early stage element Factor Gene Expression Gene expression analysis high viral load host responses include induction Infection infectious viruses interferon interferon response inverse correlation key factor limit of detection majority microflora Mild symptom mild symptoms nasopharyngeal outcome PROTECT question respiratory SARS-CoV-2 SARS-CoV-2 RNA Sequencing severe complications severe symptoms shown upper respiratory tract upregulation Viral Viral load viral loads viral pathogenesis viral strains viral titer Virological while [DOI] 10.1038/s41598-021-95197-y PMC 바로가기 [Article Type] Article
Gut Dysbiosis during COVID-19 and Potential Effect of ProbioticsReview Published on 2021-07-282022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Bifidobacteria ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 Antiviral effect association bifidobacteria binding cause cell entry characterized clinical trial Complication coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 severity dietary supplement disease Dysbiosis Effect effective Efficacy Evidence evidenced exhibiting expressed family Coronaviridae fecal gastrointestinal involvement Gut gut microbiome Health homeostasis IMPROVE infect Inflammation intestinal lactobacillus lung oral pathogen Potential Probiotics receptor RNA virus SARS-CoV-2 SARS-COV-2 infection Spike protein target therapeutic therapy tissues transmembrane protein Transmission treating COVID-19 treating COVID-19 patient [DOI] 10.3390/microorganisms9081605 PMC 바로가기 [Article Type] Review
Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Severity in COVID-19 PatientsMicrobiology Published on 2021-07-192022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] 16S rRNA gene 95% CI Analysis association Bacteria C-reactive protein changes in clinical clinical parameter Clinical severity conducted coronavirus disease COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity cross-sectional demonstrated Diversity Dysbiosis functions Gut gut microbiota gut microbiota composition Hospitalized hospitalized patient Host immune Inflammatory intensive care investigated Isolation microbial microbiota mild COVID-19 patients moderate multicenter multivariable logistic regression Multivariable regression analysis prognostic biomarker risk factor scale Sequencing severe COVID-19 Severe patient severity Shannon—Weiner diversity index the WHO was performed WHO Clinical Progression Scale [DOI] 10.3389/fmicb.2021.705020 PMC 바로가기 [Article Type] Microbiology
Taste Dysfunction and Long COVID-19Cellular and Infection Microbiology Published on 2021-07-142022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] COVID-19 Dysbiosis epithelial exfoliation Long Long COVID-19 SARS-CoV-2 Taste taste buds [DOI] 10.3389/fcimb.2021.716563 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
The human microbiome and COVID-19: A systematic review인간 미생물 군과 Covid-19 : 체계적인 검토Research Article Published on 2021-06-232022-08-13 Journal: PLoS ONE [Category] MERS, 유전자 메커니즘, [키워드] abundance alternation analyzed article association Bronchoalveolar lavage fluid changed CINAHL Cochrane Library Community conducted coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity database databases disease pathogenesis Dysbiosis eight eligible English evaluate Evidence fecal Host immune response Human humans literature review Lower respiratory tract lower respiratory tract samples lung lung tissue Microbiome microbiota microorganism microorganisms nasopharyngeal opportunistic pathogen Opportunistic Pathogens pandemic era pathogen Pathogens PROSPERO Registered remains uncertain reported Research respiratory respiratory tract respiratory viral infection Result Stool suggested symbiosis systematic review These data throat swab Viral viral infection Web of Science [DOI] 10.1371/journal.pone.0253293 PMC 바로가기 [Article Type] Research Article
Oral Microbiome Dysbiosis Is Associated With Symptoms Severity and Local Immune/Inflammatory Response in COVID-19 Patients: A Cross-Sectional StudyMicrobiology Published on 2021-06-232022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] analyzed association Bacteria clinical disease component controls coronavirus SARS-CoV-2 correlated COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients determine Dysbiosis Evidence fungi GM-CSF Gut identify IgA response IL-17 immune response Immunoglobulin Inflammation Inflammatory cytokines Local local immune response local inflammation marker microbial community Microbiome mucosal oral Oral microbiome other diseases pandemic parameter PCR primary site pro-inflammatory cytokine progression Protective quantified Replication respiratory virus response SARS-COV-2 infection secretory IgA shown significantly subjects susceptibility symptom severity symptomatic patient systemic diseases the SARS-CoV-2 therapy TNFα to define Vaccine development virus virus infection virus replication viruses WGS [DOI] 10.3389/fmicb.2021.687513 PMC 바로가기 [Article Type] Microbiology