Global Longitudinal Strain to Predict Respiratory Failure and Death in Patients Admitted for COVID-19-Related DiseaseArticle Published on 2022-02-152022-11-16 Journal: The American journal of cardiology [Category] 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory distress Admission cardiovascular system center Complete consecutive patient continuous variable COVID Cutoff death decrease detect early treatment enrolled evidence of failure fraction hazard ratio help high-risk patient higher risk Hospitalization intubation longitudinal mechanical ventilation Mortality outcome oxygen P/F Patient patients patients with COVID-19 remained respiratory Respiratory function Risk factors risk stratification secondary outcome severe disease significantly strain syndrome ventricular was performed worsening [DOI] 10.1016/j.amjcard.2021.10.046 PMC 바로가기
Posthospitalization Follow-Up of Patients With Heart Failure Using eHealth Solutions: Restricted Systematic RevieweHealth 솔루션을 사용한 심부전 환자의 입원 후 추적: 제한된 체계적 검토Review Published on 2022-02-152022-09-10 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] adherence Affect aims appraisal Care care needs CINAHL Cochrane Library controlled trials counseling COVID-19 pandemic database Effect eHealth element elements emotional emotional support examined extension failure Follow-up group heart heart failure hospital hospital discharge Hospitalization IMPROVE incidence rates information Interactive Voice Response Intervention involved item less life literature Methodological quality objective outcome Patient Patient education patient outcome posthospitalization follow-up promise provided Quality of life Randomized controlled trials readmission receive recruited reduce Reporting Research researcher Restricted Result review risk searched self-care self-monitoring Study design Support Symptom syndrome systematic review systematic reviews the patient The United States thematic analysis transition Treatment Trial United States vital signs was used [DOI] 10.2196/32946 PMC 바로가기 [Article Type] Review
Circulating Type I Interferon Levels in the Early Phase of COVID-19 Are Associated With the Development of Respiratory FailureObservational Study Published on 2022-02-142022-10-04 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] Analysis association Blood chemokine circulation collected correlated COVID-19 CXCL10 development early phase ELISA enrolled evaluate failure Hypoxemia hypoxemic IFN-I IFN-α IFN-β IFNs IL-6 interferon-alpha Interferon-beta interleukin-6 Invasion Level Ligand motif objective onset of symptoms Patient patients hospitalized patients with COVID-19 phase Pneumonia prospective observational study qPCR recruited respiratory Respiratory failure Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral load serum Serum level significantly significantly higher specimen symptom onset systemic immune response Type type I interferon Viral load was determined were measured with COVID-19 [DOI] 10.3389/fimmu.2022.844304 PMC 바로가기 [Article Type] Observational Study
Hydroxychloroquine for prophylaxis of COVID-19 in health workers: A randomized clinical trial보건 종사자의 Covid-19의 예방에 대한 하이드 록시 클로로 퀴인 : 무작위 임상 시험Randomized Controlled Trial Published on 2022-02-092022-09-10 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 임상, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 assigned baseline clinical trial Complete coronavirus coronavirus disease COVID-19 effect size Effectiveness Efficacy and safety evaluate failure HCQ Health Health care Health care worker health care workers Health personnel high risk hospitalized patient hospitalized patients Hydroxychloroquine lack negative RT-PCR outcome Patient Placebo placebo group placebo-controlled Prophylaxis Randomized randomized clinical trial refusal reported respiratory Result Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 severe acute respiratory syndrome Coronavirus severe COVID-19 severe COVID-19 patients single center statistically significant subject symptomatic infection symptomatic SARS-CoV-2 infection The effect size the placebo group Trial with COVID-19 [DOI] 10.1371/journal.pone.0261980 PMC 바로가기 [Article Type] Randomized Controlled Trial
Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial급성 저산소성 호흡부전 및 COVID-19 환자의 삽관 또는 사망에 대한 비침습적 호흡 전략의 영향: RECOVERY-RS 무작위 임상 시험Randomized Controlled Trial Published on 2022-02-082022-09-11 Journal: JAMA [Category] 유전자 메커니즘, 임상, [키워드] absolute difference Acute hypoxemic respiratory failure adaptive Adult patient Adult patients Adverse adverse events age Care clinical Clinical outcome clinical outcomes clinical trial Composite conducted Continuous Continuous Positive Airway Pressure COVID-19 COVID-19 case CPAP crossover declining determine Effect Effectiveness event failure Follow-up group HFNO High-flow nasal oxygen hospital Hospitalized hospitalized patient hospitalized patients hypoxemic Hypoxemic respiratory failure IMPROVE initial Intervention intubation Mortality no significant difference noninvasive respiratory not significantly different occurred outcome oxygen Oxygen therapy parallel group participant Participants Patient patients with COVID-19 positive airway pressure Primary outcome Randomized randomized clinical trial randomized patient receive recruitment reduced respiratory Respiratory failure risk significantly significantly lower Strategy tracheal tracheal intubation Trial Uncertainty white [DOI] 10.1001/jama.2022.0028 PMC 바로가기 [Article Type] Randomized Controlled Trial
Prediction of Conventional Oxygen Therapy Failure in COVID-19 Patients With Acute Respiratory Failure by Assessing Serum Lactate Concentration, PaO2/FiO2 Ratio, and Body TemperatureEmergency Medicine Published on 2022-02-072022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 30-Day mortality 95% CI ARF Assessing AUROC benefit Body body temperature cannulas Cohort Concentration Conventional coronavirus disease COVID COVID-19 COVID-19 patient CPAP cut-off value develop emergency department failure fraction HFNC high risk highest identify Invasive mechanical ventilation Italy Lactate lot score Masks nasal NIV non-invasive ventilation non-rebreather mask oxygen oxygen supplementation Oxygen therapy pandemic PaO paO2/fiO2 Patient patients Polyclinic positive airway pressure predict prediction Predictive presenting prognostic tool Ratio respiratory Respiratory failure respiratory therapy retrospective serum lactate significantly higher therapy university was used [DOI] 10.7759/cureus.21987 PMC 바로가기 [Article Type] Emergency Medicine
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responsesArticle Published on 2022-02-032022-10-31 Journal: Cell [Category] COVID-19, [키워드] Abstract ACE2 ACE2 binding ACE2 binding site ameliorated Analysis antibody Beta binding Booster vaccine change changes in comprehensive analysis convalescent convalescent patient COVID-19 pandemic Delta driven by Evolution facilitate failure Gamma Immune escape immune evasion mAb monoclonal antibody Mutation neutralization neutralization titers neutralize Neutralizing antibody response new SARS-CoV-2 omicron pandemic RBD receptor receptor interaction receptor-binding motif reduce reduced reduction in reported reveal SARS-CoV-2 selective sequence sera spike subject the SARS-CoV-2 titer vaccinated individual vaccine dose vaccinee vaccinees Vaccines variant variants virus viruses widespread [DOI] 10.1016/j.cell.2021.12.046 PMC 바로가기 [Article Type] Article
Nationwide external quality assessment of SARS-CoV-2 nucleic acid amplification tests in Japan일본에서 SARS-CoV-2 핵산 증폭 검사의 전국 외부 품질 평가Article Published on 2022-02-012022-09-11 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification automated cause conducted controls coronavirus COVID-19 dependent on detect diagnostics error external quality assessment failure handling highest inherent Japan Laboratory limit of detection molecular nucleic acid nucleic acid amplification nucleic acid amplification testing Other participated performance private sector public health reported respiratory RNA SARS-CoV-2 SARS-CoV-2 nucleic acid severe acute respiratory syndrome Coronavirus [DOI] 10.1016/j.ijid.2021.11.022 PMC 바로가기 [Article Type] Article
Analysis of Early Biomarkers Associated with the Development of Critical Respiratory Failure in Coronavirus Disease 2019 (COVID-19)Article Published on 2022-01-282022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acute respiratory distress Admission Analysis analyzed association Biomarker C-reactive protein Concentration consecutive patient coronavirus disease COVID-19 COVID-19 patients Cox proportional hazard CRP d -dimer death development elevated failure high-mobility group box-1 protein hospital IL-6 independent Inflammatory cytokine inflammatory mediator Injury interleukin-6 Krebs von den Lungen-6 mechanical ventilation Multivariate analysis outcome Platelet predict Protein receiver operating characteristic regression analysis reported respiratory Respiratory failure syndrome type II pneumocytes Ventilation [DOI] 10.3390/diagnostics12020339 PMC 바로가기 [Article Type] Article
First Case of a COVID-19 Patient Infected by Delta AY.4 with a Rare Deletion Leading to a N Gene Target Failure by a Specific Real Time PCR Assay: Novel Omicron VOC Might Be Doing Similar Scenario?Case Report Published on 2022-01-252022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Analysis Antigen Atypical circulating COVID-19 Deletion Delta delta variant Diagnosis diagnostic assay diagnostic tests Europe failure Genes GISAID sequence globe highlight Hospitalized Infection Interpretation Italian leading Lineage male MiSeq molecular N gene N gene target failure Nasopharyngeal swab negativity NGS novel nucleocapsid deletion nucleotides omicron Omicron variant Patient PCR performed positive result Prevalence responsible SARS-CoV-2 SARS-CoV-2 genome sequencing SARS-CoV-2 sequencing sequence Specific target time variant VoC [DOI] 10.3390/microorganisms10020268 PMC 바로가기 [Article Type] Case Report