infectious – Page 7 – Communicable Diseases Research

Comparison of seven commercial SARS-CoV-2 rapid point-of-care antigen tests: a single-centre laboratory evaluation study

7 개의 상업용 SARS-COV-2 빠른 시점 항원 테스트 비교 : 단일 센터 실험실 평가 연구

Articles

Published on 2021-07-012022-09-06
Journal: The Lancet. Microbe [Category] Communicable Disease, MERS, SARS, 치료기술,

[키워드] 95% CI Abbott Abbott Panbio COVID-19 Ag Rapid Test accelerate Affair AgPOCT AgPOCTs analytical sensitivity Antigen Antigen point-of-care test assays Biocredit COVID-19 Ag Care cassette Cell culture clinical sample clinical samples Concentration coronavirus Coronaviruses COVID-19 COVID-19 Ag Respi-Strip cross-reactivity cumulative Cumulative specificities Cumulative specificity Decision making Endemic endemic human coronavirus energy evaluated False-positive results finding FIVE foundation funding generate HCoV HCoV-HKU1 supernatant HCoV‑229E HCoV‑HKU1 HCoV‑NL63 HCoV‑OC43 Healgen Healgen assay Healgen Coronavirus Ag Rapid Test Cassette Health Health care healthy volunteer healthy volunteers Horizon Infection infectious Laboratory limit of detection Melinda Gate Melinda Gates MERS MERS-CoV Ministry of Health Most patients nal von minden nal von minden NADAL COVID-19 Ag Test outlier overlap PanBio Pathogens Patient patients point-of-care positive public health quantified R-Biopharm ranged Rapid Rapid test RapiGEN RapiGEN BIOCREDIT COVID-19 Ag real-time RT-PCR recombinant SARS-CoV-2 nucleoprotein Research respiratory respiratory pathogen Respiratory pathogens Respiratory samples RIDA Roche Roche-SD Biosensor Roche-SD Biosensor SARS-CoV Rapid Antigen Test RT-PCR SARS-CoV SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 testing SARS-CoV-2 viral load SARS-CoV-2 viral loads sensitivity Seven specificity stored respiratory sample stored respiratory samples Swab Symptoms Test test results tissue culture tissue culture supernatant tissue culture supernatants utility Viral Viral concentration Viral load viral loads virus concentration
[DOI] 10.1016/S2666-5247(21)00056-2 PMC 바로가기 [Article Type] Articles

A critical review on SARS-CoV-2 infectivity in water and wastewater. What do we know?

물과 폐수에서 SARS-CoV-2 감염성에 대한 비판적 검토. 우리는 무엇을 알고 있습니까?

Review

Published on 2021-06-202022-09-11
Journal: The Science of the total environment [Category] SARS, 치료기술,

SARS-CoV-2 seroconversions and chains of infection in healthcare professionals in a German maximum care provider (The CoSHeP study)

독일 최대 의료 제공자의 의료 전문가에서 SARS-CoV-2 혈청 전환 및 감염 연쇄(CoSHeP 연구)

Observational Study

Published on 2021-06-182022-09-10
Journal: Infection [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] age assumed Care Chains of infection Contact contact with contagious effective Elecsy emergency room FIVE Follow-up healthcare Healthcare professional healthcare professionals Healthcare-professionals higher risk hospitalized patient hospitalized patients hygiene Immunity Inclusion Infection infectious Infectious disease intensive care intensive care unit median median age observational study participant Patient patients performed Persisting immunity positive provide rate of infection remained Result reveal risk Roche Roche Elecsys Anti-SARS-CoV-2 assay SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2-IgG self-assessment Seroconversion seroconversion rate seropositive participants Symptoms through contact triggered university vaccination was measured with COVID-19
[DOI] 10.1007/s15010-021-01641-6 PMC 바로가기 [Article Type] Observational Study

Inactivation of SARS-CoV-2 virus in saliva using a guanidium based transport medium suitable for RT-PCR diagnostic assays

RT-PCR 진단 분석에 적합한 구아니듐 기반 운송 배지를 사용하여 타액에서 SARS-Cov-2 바이러스의 불 활성화

Research Article

Published on 2021-06-112022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술,

[키워드] 1:1 abrogated buffer Cell culture chain Chain Reaction clinical sample clinical samples condition conditions Copan COVID-19 CPE Cytopathic effect detect detectable diagnostic Dilution downstream evaluated expand guanidinium hazard inactivated inactivation Incubation infectious limit of detection log media medium minute passages positive processing reaction remained respiratory respiratory sample Result room temperature RT-PCR Saliva sample collection SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA SARS-CoV-2 USA-WA1/2020 SARS-CoV-2 virus stability temperature tested Transport upper VeroE6 cell VeroE6 cells Viral Viral RNA virus
[DOI] 10.1371/journal.pone.0252687 PMC 바로가기 [Article Type] Research Article

V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity

초기 전파 단계에서 나타나는 SARS-CoV-2 스파이크 RBD의 V367F 돌연변이는 증가된 인간 ACE2 수용체 결합 친화도를 통해 바이러스 감염성을 향상시킵니다

Virus-Cell Interactions

Published on 2021-06-022022-09-10
Journal: Journal of Virology [Category] SARS, 변종, 유전자 메커니즘, 진단,

[키워드] ACE2 ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity Analysis analyzed angiotensin assays binding binding affinity caused circulating coronavirus CoV COVID-19 COVID-19 pandemic Critical domain dominant dominant mutations drug ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Genome genomes hot spot Human human ACE2 human Angiotensin-converting enzyme humans in silico Increased indicated infect infectious Infectivity MDs molecular dynamics Molecular dynamics simulation molecular dynamics simulations mutant Mutation nonsynonymous Novel coronavirus pandemic of COVID-19 pangolin pangolin CoV phase Phylogenetic analysis provide Pseudotyped virus RBD RBD mutation RBD mutations receptor Receptor binding Receptor-binding domain (RBD) Recombination Research respiratory SARS-CoV-2 SARS-CoV-2 isolate SARS-CoV-2 isolates SARS-CoV-2 RBD SARS-CoV-2 spike protein SARS-CoV-2 variant selection pressure severe acute respiratory syndrome Coronavirus spike spike mutation spike mutations Spike protein Support surface plasmon surface plasmon resonance Surveillance sustained the RBD the SARS-CoV-2 trajectory Transmission V367F Vaccine Vaccines variant variants Viral viral infectivity viral tropism zoonotic infections zoonotic origin
[DOI] 10.1128/JVI.00617-21 PMC 바로가기 [Article Type] Virus-Cell Interactions

SARS-CoV-2 in hospital indoor environments is predominantly non-infectious

병원 실내 환경에서 SARS-COV-2는 주로 비 영향을 미칩니다

Research

Published on 2021-06-022022-09-10
Journal: Virology Journal [Category] MERS, SARS, 치료기술, 치료법,

[키워드] absence Complete Concentration COVID-19 Ct values degrade disease environmental sampling Future future work hospital Hospital environment in vitro In vitro infection infect Infection infectious Infectious disease Infectious virus investigated knowledge moderate non-infectious positive sample Prevent qPCR Result risk RNA RNA extraction RNase RNase A RT-qPCR SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 pandemic SARS-CoV-2 RNA SARS-CoV-2 virions SARS-CoV-2 virus Spread supplementary material the SARS-CoV-2 virus transmission route Transmission routes Treatment Uppsala University Vaccine Vero E6 Vero E6 cell VERO E6 cells Viral viral infectivity Viral RNA virus virus particle
[DOI] 10.1186/s12985-021-01556-6 PMC 바로가기 [Article Type] Research

Correlating qRT-PCR, dPCR and Viral Titration for the Identification and Quantification of SARS-CoV-2: A New Approach for Infection Management

SARS-CoV-2의 식별 및 정량화를 위한 qRT-PCR, dPCR 및 바이러스 적정의 상관관계: 감염 관리를 위한 새로운 접근 방식

Comparative Study

Published on 2021-05-282022-09-01
Journal: Viruses [Category] SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analytical methods assays can not causative agent cell cultures Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 CT Ct value Culture diagnostic diagnostic routine diagnostics dose dPCR Endpoint extraction gold gold standard identification infecting infectious methodological New pandemic polymerase chain polymerase chain reaction protocol provide purification qRT-PCR Research respiratory resulting RNA RNA copies RNA copy RNA extraction SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen TCID50/mL tissue tissue culture titration to define Viral viral burden Viral RNA viral titration Wuhan Wuhan, China
[DOI] 10.3390/v13061022 PMC 바로가기 [Article Type] Comparative Study

SARS‐CoV‐2 rapid antigen test: Fast‐safe or dangerous? An analysis in the emergency department of an university hospital

SARS-CoV-2 신속 항원 검사: 빠른 안전 또는 위험한가요? 대학병원 응급실 분석

Research Article

Published on 2021-05-092022-09-10
Journal: Journal of medical virology [Category] 진단, 치료기술,

[키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 AgPOCT Analysis Antigen Asymptomatic calculated can be used Chain Reaction coronavirus coronavirus disease Coronavirus disease 2019 COVID‐19 feasible indicate indicated infectious Inflammation information less pandemic Pandemics Patient patients PCR point of care polymerase chain polymerase chain reaction positive positive patients Positive predictive value Predictive value question respiratory SARS Coronavirus SARS‐CoV‐2 SARS‐CoV‐2 virus sensitivity severe acute respiratory syndrome Coronavirus shown specificity Symptom symptomatic and asymptomatic symptomatic and asymptomatic patients Symptoms tested the patient threshold typical symptoms university hospital without symptoms
[DOI] 10.1002/jmv.27033 PMC 바로가기 [Article Type] Research Article

Intercellular viral spread and intracellular transposition of Drosophila gypsy

초파리 집시의 세포간 바이러스 전파 및 세포내 전위

Research Article

Published on 2021-04-222022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] absence acquisition age aging ancestor animals arthropods assembly Author biological processe biological processes Cancer Cell chromosome chromosomes Combination develop disease Drosophila dysfunction element elements envelope gene Evidence exhibit exogenous retrovirus exogenous retroviruses expressed expression feature functional Genome genomes genomic germ line glial cell glial cells host genome implicated Implications incompatible increasingly infectious intercellular Like Long Long Terminal Repeat murine myriad neurodegeneration Neuron neurons occur organism plant plants Protein question raise related diseases Repeat replicate Replication retrotransposon retrotransposons retroviral retrovirus retroviruses similarity somatic cell somatic cells terminal the cell thought tissue transitioned Transmission Viral viral envelope protein viral spread Viral transmission viruses
[DOI] 10.1371/journal.pgen.1009535 PMC 바로가기 [Article Type] Research Article

Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols

비말 및 에어로졸을 통한 전염성 및 SARS-CoV-2 배출의 이질성

Meta-Analysis

Published on 2021-04-162022-08-31
Journal: eLife [Category] MERS, SARS, 신종인플루엔자, 치료제,

[키워드] Action addition aerosol Aerosols airway airways analyses Analysis Asymptomatic asymptomatic infections average Canada cause caused chair close contact collected Concentration Contact Contact tracing contagiousness cough coughing Council COVID-19 COVID-19 case COVID-19 pandemic dataset develop disease disease control droplet droplets elevated eLife emerging pathogens emerging respiratory viruses emerging viruses Engineering Epidemiology expel explain facilitate Factor greater H1N1 H1N1 virus help heterogeneity increase individual Industrial infect infecting Infection infectious Infectious disease Infectious virus infectiousness infects Influenza influenza A influenza pandemic information intrinsic lead learning limit maintain Masks mathematical Mathematical models meta-analyze minute natural new strain None Novel viruses Other outbreak overdispersion pandemic Particle pediatric people with COVID-19 post-symptom onset proportion public health question respiratory respiratory droplet Respiratory droplets respiratory tract respiratory viral respiratory viruses risk SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 virions Science social distancing Spread Subsequent infection subsequent infections superspreading superspreading event symptom onset symptomatic case symptomatic cases Symptoms systematic review Toronto Transmissibility Transmission Variability Variation Viral Virological virus virus concentration Virus concentrations virus particle virus particles viruses Volume
[DOI] 10.7554/eLife.65774 PMC 바로가기 [Article Type] Meta-Analysis