Abnormal Liver Function Tests Were Associated With Adverse Clinical Outcomes: An Observational Cohort Study of 2,912 Patients With COVID-19Medicine Published on 2021-06-092022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95%CI abnormality adjusted Admission Adverse adverse outcomes alanine aminotransferase albumin alkaline phosphatase ALP ALT Aspartate aminotransferase association AST baseline China clinical Clinical outcome collected data confounders consecutive patient coronavirus disease coronavirus disease-2019 COVID-19 Cox regression models died function homogeneous hospital Hospitalization hospitalized patient ICU ICU admission increased risk Infection intensive care large cohort Liver function liver function test abnormality mechanical ventilation median Mortality outcome outcomes parameter Patient patients required severe acute respiratory syndrome coronavirus 2 severity of COVID-19 significantly Test total bilirubin was measured with COVID-19 [DOI] 10.3389/fmed.2021.639855 PMC 바로가기 [Article Type] Medicine
Liver and Kidney Function Biomarkers, Blood Cell Traits and Risk of Severe COVID-19: A Mendelian Randomization StudyGenetics Published on 2021-05-272022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] abnormality albumin association Bilirubin Biomarker Biomarkers Blood Cell Coronavirus disease 2019 corpuscular hemoglobin COVID-19 COVID-19 pathogenesis COVID-19 severity eight Europeans Evidence function Genetic Health hematological independent individual Kidney function liver Liver function Lymphocyte count mean corpuscular hemoglobin mechanism mendelian randomization Mendelian randomization analysis neutrophil count observational studies pandemic performed remained risk risk factor Risk factors risk stratification severe COVID-19 White blood cell White blood cells [DOI] 10.3389/fgene.2021.647303 PMC 바로가기 [Article Type] Genetics
Effect of COVID-19 on liver abnormalities: a systematic review and meta‐analysisArticle Published on 2021-05-192022-10-04 Journal: Scientific Reports [Category] SARS, 임상, 치료제, [키워드] 95% CI 95% confidence interval Abnormalities abnormality acute respiratory syndrome association calculated Case report Clinical effect Coagulation coagulation parameter confounding factor coronavirus COVID-19 COVID-19 diagnosed patients database diagnosed with COVID-19 Effect epidemiological Evidence Gastrointestinal diseases Google Scholar identify Infection Interpretation liver liver diseases liver enzyme Liver function Meta-analysis observational study parameter participant Patient profile Quantitative data remained reported Sample size SARS-CoV-2 SARS-COV-2 infection searched significantly Study design systematic review total bilirubin transaminase [DOI] 10.1038/s41598-021-89513-9 PMC 바로가기 [Article Type] Article
Case Report: Viral Pneumonia Could Prompt the Advancement of Immune-Mediated Liver DiseaseMedicine Published on 2021-05-172022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] advancement Alanine Autoimmune hepatitis Case series case sery changes in COVID-19 COVID-19 outbreak described diagnosed elevated evaluated Glucocorticoids H1N1 H1N1 infection H1N1 virus Hepatitis Infection Influenza influenza A Injury liver Liver cirrhosis Liver function Liver injury Patient Pneumonia progression raise SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus the patient the SARS-CoV-2 virus therapy total bilirubin Trigger viral infection [DOI] 10.3389/fmed.2021.582620 PMC 바로가기 [Article Type] Medicine
Differences in clinical characteristics and liver injury between suspected and confirmed COVID-19 patients in Jingzhou, Hubei Province of ChinaObservational Study Published on 2021-05-142022-10-04 Journal: Medicine [Category] SARS, 임상, [키워드] acute respiratory syndrome analyzed C-reactive protein (CRP Characteristics Chest China Clinical characteristics control patients coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 patients CRP D-dimer difference disease severity Diseases Dyspnea evaluate excluded Factor Fever glucocorticoid HCT impairment involved Liver function Liver injury lymphocyte Male sex MOST Multiple Occurrence oxygen saturation patients predict predictor pulse respiratory infectious disease Retrospective study SARS-CoV-2 severity severity of COVID-19 significantly SpO2 suspected patient temperature therapeutic drug tomography Treatment was performed WBC White blood cell [DOI] 10.1097/MD.0000000000025913 PMC 바로가기 [Article Type] Observational Study
Clinical course and management of 73 hospitalized moderate patients with COVID-19 outside Wuhan우한 외 지역의 COVID-19 입원 중등도 환자 73명의 임상 경과 및 관리Research Article Published on 2021-05-132022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, 치료제, [키워드] active treatment acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission analyzed blood biochemistry Chest chest tightness clinical Clinical course coronavirus cough Course died discharge fatigue Fever Follow-up Hospitalization Hospitalized hospitalized patient hospitalized patients hyperglycemia IMPROVE Infection investigated Laboratory less Liver function lymphopenia majority management median median age medical record medical records men moderate myocardial enzymes nucleic acid nucleic acid test on admission Patient patients with COVID-19 positive positively correlated Prognosis proportion recurrence respiratory SARS-CoV-2 SARS-CoV-2 patient SARS-CoV-2 patients severe acute respiratory syndrome Coronavirus survivor Survivors Symptom Symptoms the median the SARS-CoV-2 Treatment Viral Viral detection virus carrier virus carriers women Wuhan [DOI] 10.1371/journal.pone.0249655 PMC 바로가기 [Article Type] Research Article
The effect of Chinese herbal medicine on digestive system and liver functions should not be neglected in COVID-19: An updated systematic review and meta-analysisMeta-Analysis Published on 2021-05-012023-06-19 Journal: Iubmb Life [Category] MERS, [키워드] Chinese herbal medicine Coronavirus disease 2019 gastrointestinal symptoms Liver function Meta-analysis [DOI] 10.1002/iub.2467 PMC 바로가기 [Article Type] Meta-Analysis
Liver injury is independently associated with adverse clinical outcomes in patients with COVID-19간 손상은 COVID-19 환자의 불리한 임상 결과와 독립적으로 연관되어 있습니다Article Published on 2021-04-012022-09-11 Journal: Gut [Category] SARS, 치료제, [키워드] 95% CI acute respiratory syndrome adjusted Admission admitted to ICU age Alanine alanine aminotransferase albumin ALT/AST aspartate Aspartate aminotransferase AST Beta Biochemistry cholestasis Clinical outcome coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids COVID-19 COVID-19 patient COVID-19 patients database death defined diabete diabetes Diagnosis died HCoV HCoVs Hepatitis Hong Kong human coronavirus hypertension ICU Injury intensive care intensive care unit interferon interferon beta Invasive mechanical ventilation limit liver Liver function Liver function test Liver injury Lopinavir Lopinavir-ritonavir men occurred Patient patients patients with COVID-19 primary end point retrospective cohort study ribavirin Ritonavir SARS patient SARS patients Severe acute respiratory syndrome Virological [DOI] 10.1136/gutjnl-2020-321726 PMC 바로가기 [Article Type] Article
The role of teicoplanin in the treatment of SARS‐CoV‐2 infection: A retrospective study in critically ill COVID‐19 patients (Tei‐COVID study)Observational Study Published on 2021-03-262022-10-04 Journal: Journal of medical virology [Category] SARS, 임상, 치료제, [키워드] acute respiratory syndrome analysed Analysis Antibiotics Antiviral antiviral activity Biochemical parameters BSI C‐reactive protein causative pathogen Clinical stages Cohort complementary control group controls coronavirus coronavirus disease correlated Course COVID COVID‐19 COVID‐19 patient COVID‐19 Critically ill Critically ill patient critically ill patients Day effective empiric antibiotic enrolled evaluate expressed glycopeptide Hospitalization Hospitalized ICU ICUs infected patient intensive care unit kidney lack Liver function lymphocyte mechanical ventilation Mortality onset of disease outcome pathogenic mechanism Patient patients Pneumonia Primary outcome reduced reducing Research respiratory viral infection retrospective Retrospective study SARS‐CoV‐2 SARS‐CoV‐2 several limitation Side effect significantly Staphylococcus aureus statistical statistical significance statistically significant difference suggested sustained Teicoplanin the disease therapeutic therapy treat treated Treatment two group viral clearance viral damage viral replication virus White blood cell [DOI] 10.1002/jmv.26925 PMC 바로가기 [Article Type] Observational Study
Nomogram for prediction of fatal outcome in patients with severe COVID-19: a multicenter study중증 COVID-19 환자의 치명적인 결과 예측을 위한 노모그램: 다기관 연구Multicenter Study Published on 2021-03-172022-09-12 Journal: Military Medical Research [Category] 진단, [키워드] 95% CI Admission Analysis analyzed Blood C-reactive protein Chest computed tomography clinician Coagulation Cohort COVID-19 COVID-19 patient CRP death develop effective enrolled Factor help high risk hospital identify IL-6 IMPROVE independent indicated interleukin-6 Laboratory test Liver function Lymphocyte count Mortality multicenter multivariate nomogram observation outcome oxygen saturation Patient patients PCT predict prediction Probability procalcitonin Prognosis prognostic pulse receiving reduce renal function Result routine blood tests sensitivity serological severe coronavirus disease severe COVID-19 severe COVID-19 patient severe COVID-19 patients Severe patient severe patients specificity supplementary material survival Tocilizumab treatment strategy validation cohort validation cohorts was measured [DOI] 10.1186/s40779-021-00315-6 PMC 바로가기 [Article Type] Multicenter Study