mendelian randomization – Page 7 – Communicable Diseases Research

Causal Association and Shared Genetics Between Asthma and COVID-19

천식과 COVID-19 사이의 인과 관계 및 공유 유전학

Meta-Analysis

Published on 2022-03-212022-09-11
Journal: Frontiers in Immunology [Category] SARS, 변종, 유전자 메커니즘,

[키워드] 95% confidence interval ABO analyses Analysis Asthma ATXN2 Causal Causality conducted connection controls COVID-19 COVID-19 case COVID-19 disease COVID-19 hospitalization COVID-19 infection early stage Effect evaluate Genes Genetic Genetic variant genetic variants genome-wide significant GWAS hospitalized COVID-19 Inflammation loci mechanism mendelian randomization Meta-analysis OAS2 Odds ratio outcome outcomes pleiotropic effect Pleiotropic effects protective effect Protective effects recent responses against risk SARS-CoV-2 severe COVID-19 disease susceptibility variant variants was performed were used
[DOI] 10.3389/fimmu.2022.705379 PMC 바로가기 [Article Type] Meta-Analysis

Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19

Proteome wide Mendelian Randomization은 혈액 단백질과 심한 covid-19 사이의 인과 관계를 식별합니다

Research Article

Published on 2022-03-032022-09-10
Journal: PLoS Genetics [Category] MERS, SARS, 바이오마커, 진단,

[키워드] ABO applied assumption ATP2A3 binding Biology Biomarker Blood Blood Group Blood level blood levels blood protein blood proteins C1GALT1C1 causal link CD207 Cell contrary COVID-19 COVID-19 pandemic death decrease died disease pathology enzyme FAAH2 facilitate FIVE form forms GCNT4 genetic instrument genetic instruments Hospitalization ICAM-1 identify implicated increased risk individuals investigated involved KEL LCTL lead marker mendelian randomization multiple testing outcome pathophysiology Potential biomarker potential biomarkers Protein RAB14 replicate Research respiratory Respiratory Support risk SELE SELL severe COVID-19 severe forms of COVID-19 severity SFTPD surpassed target targets vaccination Vaccinations with COVID-19
[DOI] 10.1371/journal.pgen.1010042 PMC 바로가기 [Article Type] Research Article

Genetic Predisposition to Coronavirus Disease 2019 in Relation to Ten Cardiovascular Conditions: A Two-Sample Mendelian Randomization Study

Medicine

Published on 2022-02-172022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

A Narrative Review of the Evidence for Variations in Serum 25-Hydroxyvitamin D Concentration Thresholds for Optimal Health

Review

Published on 2022-02-022022-10-31
Journal: Nutrients [Category] COVID-19, COVID19(2023년),

Influence of Nutritional Intakes in Japan and the United States on COVID-19 Infection

Article

Published on 2022-02-012022-10-30
Journal: Nutrients [Category] COVID-19,

Total body bone mineral density and severe COVID-19: A Mendelian randomization analysis in five age strata

Correspondence

Published on 2022-02-012022-10-05
Journal: Bone [Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] age Aged population Analysis COVID-19 FIVE mendelian randomization Total Total body bone mineral density
[DOI] 10.1016/j.bone.2021.116281 [Article Type] Correspondence

Cancer and COVID-19 Susceptibility and Severity: A Two-Sample Mendelian Randomization and Bioinformatic Analysis

Cell and Developmental Biology

Published on 2022-01-242022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

[키워드] addition Affect alteration Analysis analyzed anticancer approach association Bioinformatic Cancer cancer progression cancer type cancers Chemotherapy Clinical management Consensus COVID-19 COVID-19 disease severity COVID-19 severity COVID-19 susceptibility death demonstrated Deterioration differential expression ERAP2 example expression pattern Genetic Genetic predisposition GWAS heterogeneity implication information introduced involved less lung lung adenocarcinoma mendelian randomization Mutation outlier Patient patients patients with COVID-19 Pleiotropy Prognosis prognostic reached reduce reliability risk factor severity SNP SNPs statistical significance supported Surveillance susceptibility Treatment upregulated with COVID-19
[DOI] 10.3389/fcell.2021.759257 PMC 바로가기 [Article Type] Cell and Developmental Biology

Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging

Research

Published on 2022-01-202022-10-05
Journal: Nature Aging [Category] 바이오마커, 유전자 메커니즘,

Non-Causal Effects of Asthma on COVID-19 Susceptibility and Severity

Genetics

Published on 2022-01-102022-10-31
Journal: Frontiers in Genetics [Category] COVID-19,

The Effect of Circulating Zinc, Selenium, Copper and Vitamin K 1 on COVID-19 Outcomes: A Mendelian Randomization Study

순환하는 아연, 셀레늄, 구리 및 비타민 K 1이 COVID-19 결과에 미치는 영향: 멘델식 무작위 배정 연구

Article

Published on 2022-01-062022-09-10
Journal: Nutrients [Category] 변종,

[키워드] 95% CI aims Analysis Anti-viral association circulating copper COVID-19 COVID-19 infection Critical Critical illness Effect Evidence evidence of Genetic variant GWAS Hospitalization immunomodulatory activities in vitro experiment increase in Infection inverse-variance weighted IVW liberal mendelian randomization Micronutrient MR-Egger Odds ratio outcome outcomes P -value predicted Prevent Prophylaxis red blood cell red blood cells reflected Result risk of infection SARS-CoV-2 SARS-COV-2 infection selection of variant Selenium Sensitivity analyses sensitivity analysis serum/plasma threshold Treatment treatment of COVID-19 variants Vitamin vitamin K vitamin K₁ was obtained with COVID-19 Zinc
[DOI] 10.3390/nu14020233 PMC 바로가기 [Article Type] Article