mesenchymal stem cell – Page 7 – Communicable Diseases Research

Potential of Immune-Related Therapy in COVID-19

Pharmacology

Published on 2021-01-262022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

Mesenchymal stem cell (MSC)-derived exosomes as a cell-free therapy for patients Infected with COVID-19: Real opportunities and range of promises

중간엽줄기세포(MSC) 유래 엑소좀, 코로나19 감염 환자를 위한 무세포 치료제로 활용: 진정한 기회와 약속의 범위

Review

Published on 2021-01-012022-09-11
Journal: Chemistry and physics of lipids [Category] SARS, 임상, 치료제,

[키워드] acute respiratory distress acute respiratory distress syndrome antiviral medication Antiviral medications ARDS carrier carriers cells clinical trial coronavirus disease COVID-19 death derivative drugs effective Exosome Exosome based therapy Exosomes include induce Inflammation Intercellular communication medical need mesenchymal stem cell Mesenchymal stem cells miRNA miRNAs MOST mRNA mRNAs MSC MSC exsosomes Novel coronavirus novel coronavirus disease Patient Potential potential therapy respiratory distress second Secretome shown stem cell suppress syndrome therapy transfer Treatment treatment of COVID-19 Vaccine virus
[DOI] 10.1016/j.chemphyslip.2020.105009 PMC 바로가기 [Article Type] Review

Umbilical cord: an allogenic tissue for potential treatment of COVID-19

탯줄: COVID-19의 잠재적인 치료를 위한 동종 조직

Review

Published on 2021-01-012022-09-11
Journal: Human Cell [Category] 임상,

[키워드] acute respiratory distress acute respiratory distress syndrome alveolar alveolar damage ARDS associated symptoms autologous best chemokine chemokines clinical Clinical studies clinical study compassionate use complications controlled trials coronavirus COVID-19 COVID-19 pandemic Cytokines demonstrated detrimental effective Efficacy Evidence Factors globe Health care Health care system health care systems Hope immunomodulatory immunomodulatory effect lead limitations manuscript mesenchymal stem cell Mesenchymal stem cells MSC MSCs organ damage positioned Potential treatment pro-inflammatory cytokine pro-inflammatory cytokines randomized, controlled trial reduce regenerative respiratory distress Respiratory distress syndrome Safe SARS-COV-2 infection Symptom Symptoms syndrome therapeutic use therapy for COVID-19 tissue tissue repair treat Treatment treatment of COVID-19 umbilical Umbilical cord Vaccine Wharton's Jelly Wharton’s jelly Wharton’s jelly.
[DOI] 10.1007/s13577-020-00444-5 PMC 바로가기 [Article Type] Review

The Systematic Effect of Mesenchymal Stem Cell Therapy in Critical COVID-19 Patients: A Prospective Double Controlled Trial

중증 코로나19 환자에서 중간엽 줄기세포 치료의 체계적인 효과: 전향적 이중 대조 시험

Controlled Clinical Trial

Published on 2021-01-012022-09-11
Journal: Cell transplantation [Category] 유전자 메커니즘, 임상,

[키워드] Analysis anti-inflammatory cytokine anti-inflammatory cytokines Apoptosis Biochemical parameters CD16 CD19 CD3 CD4 CD45 CD56 CD8 Cell cellular chemokines clinical manifestation clinical manifestations clinical trial Controlled COVID-19 COVID-19 patient COVID-19 patients Critical critical cases Critically ill critically ill COVID-19 patients critically ill patients CRP level CRP levels cytokine Cytokine storm Cytokines demonstrated died dose Effect evaluate evaluated fibrinogen group groups growth growth factor Growth factors HLA-DR IFNγ IL-10 IL-12 IL-13 IL-17A IL-1ra IL-2 IL-6 immunomodulatory effect immunomodulatory effects intravenously investigated KGF lymphocyte Lymphocyte subsets marker matrix metalloproteinases mechanism of action mesenchymal stem cell Mesenchymal stem cells moderate MSC MSCs Neutrophils NGF overall mortality Patient positive proinflammatory proinflammatory cytokines Prospective reducing mortality separated Serum ferritin significantly statistical STEM stem cell TGF-β the cytokine storm therapy tissue regeneration treated Treatment VEGF
[DOI] 10.1177/09636897211024942 PMC 바로가기 [Article Type] Controlled Clinical Trial

A Retrospective Look at Recent COVID-19 Articles Published in Cell Transplantation: Research Leading to Further Understanding

세포 이식에 게재된 최근 COVID-19 기사에 대한 회고적 검토: 더 많은 이해를 이끄는 연구

Article

Published on 2021-01-012022-09-11
Journal: Cell transplantation [Category] 변종,

[키워드] ACE2 acute respiratory diseases androgen Androgen receptors angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 article cell transplantation cellular cellular therapy Characteristics consequence COVID-19 COVID-19 pandemic COVID-19 severity Cytokines disease disease severity enzyme Genes group Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients immune infused Intervention leading mesenchymal stem cell Mesenchymal stem cells modulating MSC offered pandemic Perspective principle proof recent receptor reduced Research respiratory diseases SARS-CoV2 Serine stem cells supported the disease therapy TMPRSS2 transmembrane serine protease transplantation Treatment understanding unique Variability variant variants
[DOI] 10.1177/09636897211049814 PMC 바로가기 [Article Type] Article

Efficacy and safety of mesenchymal stem cells for the treatment of patients infected with COVID-19: a systematic review and meta-analysis protocol

코로나19 환자 치료를 위한 중간엽줄기세포의 효능 및 안전성: 체계적 고찰 및 메타분석 프로토콜

Article

Published on 2020-12-182022-08-31
Journal: BMJ Open [Category] MERS, meta-analysis, SARS,

[키워드] academic conference adverse events antivirus drug assessment bias risk Biomarker Biomarkers Case series case sery CBM Cell Cell Biology changes in chest pain China Chinese CINAHL CNKI Cochrane Library collected conducted Controlled trial COVID-19 pandemic critical cases data extraction database development Dexamethasone difficulty difficulty breathing dose duration of fever Efficacy and safety eligibility criteria Ethical approval Ethics evaluate Evidence high mortality immunology inception incidence include Infectious diseases Infrastructure journal Laboratory laboratory examination life literature mesenchymal stem cell Meta-analysis Mild moderate moderate to severe Mortality movement MSC MSC therapy Patient patients with COVID-19 peer-reviewed performed pressure Prevent Primary outcome Primary outcomes progression PROSPERO protocol public health Quality of life Randomised controlled trials reduce registration number respiratory searched secondary outcome Secondary outcomes sensitivity analysis service severity Shortness of breath SinoMed speech stem cell strength Symptom System systematic review Therapeutic approach therapy treat Treatment Vaccine ventilator VIP Web of Science
[DOI] 10.1136/bmjopen-2020-042085 PMC 바로가기 [Article Type] Article

Mesenchymal Stem Cells (MSCs) as a Potential Therapeutic Strategy in COVID-19 Patients: Literature Research

Cell and Developmental Biology

Published on 2020-11-192022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

[키워드] anti-inflammatory activity ARDS Biology cell-based therapies Cell-based therapy Characteristics China coronavirus COVID-19 COVID-19 disease COVID-19 patients Critical Critical case Cytokine storm dimension effective therapy Engineering Health literature lung Medicine mesenchymal stem cell Mesenchymal stem cells MSC MSCs outbreak outcome pandemic Pathologies Pneumonia positive Potential Pulmonary edema pulmonary inflammation raised reported representing respiratory responsible SARS-CoV-2 Secretome shown specific treatment STEM Strategy Symptoms symptoms of COVID-19 therapeutic potential therapeutic strategy these cell Treatment Vaccine were used
[DOI] 10.3389/fcell.2020.602647 PMC 바로가기 [Article Type] Cell and Developmental Biology

Transplantation of Mesenchymal Stem Cells: A Potential Adjuvant Therapy for COVID-19

Bioengineering and Biotechnology

Published on 2020-11-052022-10-31
Journal: Frontiers in Bioengineering and Biotechnology [Category] COVID-19,

Insights into the use of mesenchymal stem cells in COVID-19 mediated acute respiratory failure

Review Article

Published on 2020-10-262022-10-04
Journal: NPJ Regenerative Medicine [Category] 임상, 치료제,

Potential application of mesenchymal stem cells and their exosomes in lung injury: an emerging therapeutic option for COVID-19 patients

Review

Published on 2020-10-152022-10-29
Journal: Stem Cell Research & Therapy [Category] COVID-19, MERS, SARS,

[키워드] acute lung injury alveolar fluid clearance applicability approved ARDS characterized clinical study clinical trial clinical trials Consensus correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients effective effective therapy Efficacy endothelial ENhance epithelial Exosome global public health highlight impacted Infection International less lung mechanism of action mesenchymal stem cell MSC MSC therapy MSCs Pneumonia Potential promote reduce Registered risk Safe SARS-CoV-2 stem cell stem cells the cytokine storm the SARS-CoV-2 therapeutic therapeutic effect therapeutic option therapy Thromboembolism treat treating COVID-19 patients Treatment unique
[DOI] 10.1186/s13287-020-01963-6 PMC 바로가기 [Article Type] Review