Cell-free DNA maps COVID-19 tissue injury and risk of death and can cause tissue injury
무세포 DNA는 COVID-19 조직 손상과 사망 위험을 매핑하고 조직 손상을 유발할 수 있습니다.
Multicenter Study
[키워드] (cfDNA
adipocytes
Admission
Analysis
analyzed
bioinformatics
Biomarker
bisulfite
bisulfite sequencing
C-reactive protein
cell-free DNA
cfDNA
Clinical course
Comparator group
conducted
contribute
coronavirus
Coronavirus 2019
correlation
COVID-19
COVID-19 disease
COVID-19 disease severity
COVID-19 patient
D-dimer
death
died
disease severity
DNA
DNA methylation
elevated
funding
healthy control
healthy controls
heart
hematopoietic cells
hepatocytes
heterogeneous
Hospitalization
Inflammation
Influenza
inhibited
Injury
intensive care
Intramural
kidney
library
lung
measure
Mild
mitochondrial
Molecular genetics
multicenter
multiorgan failure
NIH
outcome
outcomes
Patient
patients with COVID-19
performed
plasma samples
positively correlated
predict
prospective cohort study
renal tubular cell
renal tubular cells
required
respiratory syncytial virus
risk of death
ROS
sequence
subject
tissue
tissue injury
tissue source
TLR9
to define
Trajectories
tubular cells
Vascular endothelium
was used
with COVID-19
[DOI] 10.1172/jci.insight.147610 PMC 바로가기 [Article Type] Multicenter Study
[DOI] 10.1172/jci.insight.147610 PMC 바로가기 [Article Type] Multicenter Study