European multicenter evaluation of Xpert® Xpress SARS‐CoV‐2/Flu/RSV testResearch Article Published on 2021-06-062022-11-01 Journal: Journal of medical virology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome average Clinical sign coronavirus correlation COVID‐19 diagnostics Epidemics Europe European evaluated highest Influenza influenza A influenza B less multicenter multiplex Multiplex PCR nasopharyngeal pandemic pathogen positive Rapid respiratory syncytial virus RSV SARS‐CoV‐2 SARS‐CoV‐2 sensitivity Spread Symptom target targets tested throat swab upper respiratory tract [DOI] 10.1002/jmv.27111 PMC 바로가기 [Article Type] Research Article
Viral epidemiology and SARS‐CoV‐2 co‐infections with other respiratory viruses during the first COVID‐19 wave in Paris, FranceShort Article Published on 2021-04-042022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] COVID-19, MERS, SARS, [키워드] age Clinical characteristics COVID‐19 Epidemiology Fever First wave France headache hospital ILI infections Multiplex PCR objective other respiratory virus Paris Patient patients patients hospitalized positive presenting Prevalence Prognosis respiratory viruses Result SARS‐CoV‐2 SARS‐CoV‐2‐infected SARS‐CoV‐2 Symptoms syndromic testing tested viral co‐infection [DOI] 10.1111/irv.12853 PMC 바로가기 [Article Type] Short Article
The Unyvero Hospital-Acquired pneumonia panel for diagnosis of secondary bacterial pneumonia in COVID-19 patients유니베로병원 획득 폐렴 패널, 코로나19 환자 2차 세균성 폐렴 진단Original Article Published on 2021-03-042022-09-10 Journal: European Journal of Clinical Microbiology & Infect [Category] SARS, 치료기술, [키워드] 95% CI 95%CI application bacterial pathogen Bacterial pathogens bacterial pneumonia bacterial species bacterial specy carried Concordance COVID-19 COVID-19 patient Critically ill critically ill COVID-19 patients Culture demonstrated Diagnosis diagnostic evaluate Hospital-Acquired pneumonia HPN Lower respiratory tract LRT multiplex Multiplex PCR Multiplex-PCR Negative predictive value Pathogens PCR-based method performance Pneumonia positive predictive values Rapid-diagnostic tests reference method residual respiratory secondary bacterial pneumonia sensitivity SOC specificity Standard-of-care supplementary material tested were used [DOI] 10.1007/s10096-021-04194-6 PMC 바로가기 [Article Type] Original Article
A rapid and cost‐effective multiplex ARMS‐PCR method for the simultaneous genotyping of the circulating SARS‐CoV‐2 phylogenetic cladesResearch Article Published on 2021-02-012022-10-04 Journal: Journal of medical virology [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome amplification annealing temperature ARMS circulating clade clades complementary Concentration coronavirus costly COVID‐19 DNA FIVE genotyping identify multiplex Multiplex PCR mutated Mutation mutations PCR PCR condition Phylogenetic phylogenetically polymerase chain primer Primers Sanger sequencing SARS‐CoV‐2 SARS‐CoV‐2 Sequencing tracing variant [DOI] 10.1002/jmv.26818 PMC 바로가기 [Article Type] Research Article
Co-infection in patients with hypoxemic pneumonia due to COVID-19 in Reunion IslandObservational Study Published on 2021-01-292022-10-04 Journal: Medicine [Category] 임상, [키워드] 229E absence Co-infection Cohort collected commenced conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case Culture D-dimer D-dimer level database elevated evaluate expected France H1N1 Haemophilus influenzae hospital human coronavirus hypoxemic incidence Influenza Influenza virus island limitations multiplex Multiplex PCR pathogen Patient PCR Pneumonia polymerase chain required SARS-CoV-2 screened Spain specific treatment sputum culture Staphylococcus aureus Streptococcus pneumoniae Treatment university [DOI] 10.1097/MD.0000000000024524 PMC 바로가기 [Article Type] Observational Study
Novel dual multiplex real-time RT-PCR assays for the rapid detection of SARS-CoV-2, influenza A/B, and respiratory syncytial virus using the BD MAX open systemBD MAX 개방형 시스템을 사용하여 SARS-CoV-2, 인플루엔자 A/B 및 호흡기 세포융합 바이러스의 신속한 검출을 위한 새로운 이중 다중 실시간 RT-PCR 분석Coronaviruses Published on 2021-01-192022-09-10 Journal: Emerging Microbes & Infections [Category] SARS, 치료기술, [키워드] analysed BD MAX BD MAX platform Chain Reaction clinical sample clinical samples Coinfection common cold comparable COVID-19 death demonstrated dual evaluated individual Infection Influenza limit of detection multiplex Multiplex PCR nasopharyngeal nasopharyngeal specimen Nasopharyngeal swab novel nucleic acid nucleic acid extraction open Pathogens polymerase chain reaction positive provide Real-time PCR real-time reverse transcription-polymerase chain reaction real-time RT-PCR respiratory respiratory syncytial virus respiratory tract infection RNA standards robust RSV RT-PCR RT-PCR test SARS-CoV-2 sensitivity simultaneous detection Spread Symptom System Taiwan upper respiratory tract upper respiratory tract infection Viral viral pathogen viral pathogens [DOI] 10.1080/22221751.2021.1873073 PMC 바로가기 [Article Type] Coronaviruses
Tissue-Specific Immunopathology in Fatal COVID-19치명적인 COVID-19의 조직 특이적 면역병리학Original Articles Published on 2021-01-152022-09-10 Journal: American Journal of Respiratory and Critical Care [Category] 치료기술, 치료제, [키워드] aberrant immune response aberrant macrophage and plasma-cell responses acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition anatomic sites arteritis Autopsy cellular distribution cellular resolution characterized coronavirus coronavirus disease Corticosteroid Corticosteroids COVID-19 death deleterious inflammation determine direct reaction effort evidence of excessive reactive plasmacytosis fatal COVID-19 highlight Histologic evidence immune response immune responses Immune-mediated independent immunopathologic process Inflammation influx iron iron-laden macrophages life-threatening coronavirus disease lung lymphoid tissues Macrophage macrophage/monocyte-lineage cell macrophage/monocyte-lineage cells macrophages mapped measurement monocyte/myeloid-rich vasculitis Multiple Multiple aberrant immune responses multiplex immunofluorescence Multiplex PCR novel immunopathologic mechanism novel immunopathologic mechanisms occur occurred organ dysfunction organ injury organ-specific inflammatory response organ-specific inflammatory responses organotropism pathogen tolerance postmortem examinations primary mechanism promote Protein pulmonary immune response pulmonary parenchyma quantified rationale reduce mortality respiratory response responses reticuloendothelial reticuloendothelial system SARS-CoV-2 SARS-CoV-2 RNA Sequencing severe acute respiratory syndrome Coronavirus severe disease significant component stereotyped abnormal reticuloendothelial responses therapeutically target tissue Tissue-specific immunopathology tissues Vasculitis Viral viral presence viral S virus virus-independent immunopathologic process [DOI] 10.1164/rccm.202008-3265OC PMC 바로가기 [Article Type] Original Articles
Does respiratory co-infection facilitate dispersal of SARS-CoV-2? investigation of a super-spreading event in an open-space officeResearch Published on 2020-12-022022-10-28 Journal: Antimicrobial Resistance and Infection Control [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Adenovirus calculated carried close contact Co-infection coronavirus Coronavirus disease 2019 COVID-19 diagnosed dispersal event facilitate facilitated Factor Genome sequence data hygiene identify index case individual infecting information joint Measures Multiplex PCR outbreak Outbreak investigation physical distancing Potential precluded reported respiratory viral Result retrospective cohort study SARS-CoV-2 SARS-CoV-2 transmission secondary attack rate sequence sequencing approach serotype Super-spreader Super-spreading Symptoms Transmission transmission of SARS-CoV-2 was performed were assessed whole-genome sequencing [DOI] 10.1186/s13756-020-00861-z PMC 바로가기 [Article Type] Research
Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon AntagonismArticle Published on 2020-10-142022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Amplicon antagonism assays cDNA clinical sample coronavirus coronavirus disease Coronaviruses COVID-19 Deletion deletions detection diagnostic driver Factor generate genetic change Genome identification identify impair insertion isolate Long MinION Molecular epidemiology Multiplex PCR Next-generation sequencing nucleotide change occur outbreak Oxford pathogenic Patient platform Point mutation primer proportion protocol random Rapid Real-time PCR Recombination Replication RNA purified RT-PCR SARS-CoV-2 sequence Sequencing sequencing approach Single nucleotide polymorphism the SARS-CoV-2 genome variety viral genome Viral RNA virus was used [DOI] 10.3390/v12101164 PMC 바로가기 [Article Type] Article
Interference between rhinovirus and influenza A virus: a clinical data analysis and experimental infection study라이노바이러스와 인플루엔자 A 바이러스의 간섭: 임상 데이터 분석 및 실험적 감염 연구Article Published on 2020-10-092022-09-10 Journal: The Lancet. Microbe [Category] MERS, 신종인플루엔자, 치료기술, [키워드] 95% CI Affect airway Analysis Antiviral blocking Cell culture cell cultures Clinical data co-occurrence Course COVID-19 pandemic Culture decrease Department Epidemic Epidemics epithelial Europe European country examination expected expression finding fluorescent Frame funding GFP green fluorescent protein H1N1 H1N1pdm09 host cell IAV idea inclusion criteria indicated Infection Influenza influenza A influenza A virus inhibit inoculated Interference interferon interferon response interferon-stimulated gene interferon-stimulated genes Intervention ISG ISGs medical record Medical Sciences Medicine Microscopy mock infection MOI mRNA mucosa Multiplex PCR multiplicity multiplicity of infection Odds ratio pandemic positive Post-infection primary human airway Protein quantitative PCR Replication reporter respiratory respiratory sample Respiratory samples respiratory specimen respiratory specimens respiratory virus restored resulting reverse transcription Reverse transcription quantitative PCR rhinovirus RNA Seasonal influenza significantly lower Spread Stimulation subsequent System tested the interferon Time frame USA Viral Viral RNA virus was used [DOI] 10.1016/s2666-5247(20)30114-2 PMC 바로가기 [Article Type] Article