Neutralizing activity – Page 7 – Communicable Diseases Research

Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Boosts Neutralizing Activity Against Seasonal Human Coronaviruses

중증 급성 호흡기 증후군 코로나바이러스 2 백신 접종은 계절성 인간 코로나바이러스에 대한 중화 활성을 향상시킵니다

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료법,

Reduced Immune Response to Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Cohort of Immunocompromised Patients in Chile

칠레의 면역 저하 환자 집단에서 비활성화된 중증 급성 호흡기 증후군 코로나바이러스 2 백신에 대한 면역 반응 감소

Article

Published on 2022-08-242022-09-12
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단,

[키워드] acute respiratory syndrome anti-SARS-CoV-2 antibody Autoimmune Cancer Cell clinical concentrations conducted control group controls CoronaVac coronavirus coronavirus 2 COVID-19 dose Enrollment evaluate groups HIV HIV group Human immunodeficiency virus humoral immune response Immunocompromised Immunocompromised patient immunocompromising condition Immunoglobulin Inactivated vaccine Infection interferon γ median Neutralizing activity not differ not significant participant patients prospective cohort study receiving Red reduce respiratory response rheumatic disease SARS-CoV-2 significantly solid organ transplant solid tumor T cell T-cell Response Trial Vaccination strategy Vaccine vulnerable patients
[DOI] 10.1093/cid/ciac167 PMC 바로가기 [Article Type] Article

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

포괄적인 백신 패널에 의해 유도된 오미크론 스파이크 기능 및 중화 활성

Article

Published on 2022-08-192022-09-11
Journal: Science (New York, N.y.) [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

BNT162b2-boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19

COVID-19에 대한 이종 또는 동종 ChAdOx1nCoV-19/BNT162b2 백신 접종 후 6개월 후 BNT162b2로 강화된 면역 반응

Article

Published on 2022-08-182022-09-11
Journal: Nature Communications [Category] SARS, 변종, 임상, 진단, 치료기술, 치료법,

Heterogenous humoral and cellular immune responses with distinct trajectories post-SARS-CoV-2 infection in a population-based cohort

인구 기반 코호트에서 SARS-CoV-2 감염 후 뚜렷한 궤적을 가진 이종 체액성 및 세포성 면역 반응

Article

Published on 2022-08-182022-09-11
Journal: Nature Communications [Category] SARS, 변종, 진단, 치료기술, 치료법,

[키워드] Analysis anti-N IgG anti-S responses antibody Antibody responses Cellular immune response cellular immunity cellular response characterized clinical factors Cluster analyses Delta detectable develop Diagnosis FIVE heterogeneity humoral humoral and cellular immunity Humoral and cellular responses identify IgA IgG immune Immunity individual infected individuals Infection maintain membrane Neutralizing activity neutralizing antibody omicron Omicron variants Participants population-based cohort required responses S proteins SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected individual T cell T cell response T cell responses T cells trajectory variant
[DOI] 10.1038/s41467-022-32573-w PMC 바로가기 [Article Type] Article

Heterologous immunization with adenovirus vectored and inactivated vaccines effectively protects against SARS-CoV-2 variants in mice and macaques

Article

Published on 2022-08-172022-11-15
Journal: Frontiers in Immunology [Category] SARS, 변종, 진단,

[키워드] Activation Adenovirus adenovirus vectored vaccine animal model animal models antibody booster caused COVID-19 COVID-19 vaccine demonstrated effective Effectiveness expressing Heterologous heterologous immunization homologous immunization Inactivated vaccine Invasion Lung injury macaque mice Neutralizing activity NHP NHPs non-human primate omicron priming PROTECT Protective protective effectiveness. reduced regimen Regulation risk SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variant SARS-CoV-2 variants spike-specific antibody response T cell T cell response upregulating vaccination Vaccine-induced immunity variant virus was tested
[DOI] 10.3389/fimmu.2022.949248 PMC 바로가기

Cross-Neutralization of SARS-CoV-2-Specific Antibodies in Convalescent and Immunized Human Sera against the Bat and Pangolin Coronaviruses

박쥐 및 천산갑 코로나바이러스에 대한 회복기 및 면역화된 인간 혈청에서 SARS-CoV-2-특이적 항체의 교차 중화

Article

Published on 2022-08-162022-09-12
Journal: Viruses [Category] SARS, 진단,

[키워드] ACE2 analyzed appear bat bat coronavirus binding Cell cell-cell fusion chimeric chimeric proteins contribute coronavirus COVID-19 COVID-19 patient cross-neutralize highest Human human ACE2 receptor human host immunized inactivated induce less neutralization neutralization activity neutralized Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody overexpressing pandemic pangolin pangolin coronavirus pangolins pre-existing immunity promote Protein pseudo-virus pseudo-virus. RaTG13 RBD replaced sarbecovirus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine serum sample significantly significantly higher spike the RBD the receptor-binding domain thought transmitted vaccination VeroE6 cells while widespread
[DOI] 10.3390/v14081793 PMC 바로가기 [Article Type] Article

Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1

Alpha에서 Omicron BA.1까지 변이체를 교차 중화하는 조상 SARS-CoV-2 균주에 의해 유도된 항체

Article

Published on 2022-08-122022-09-11
Journal: Science Immunology [Category] Fulltext, SARS, 변종, 진단,

[키워드] ACE2 binding antibodies antibody B cell binding binding site breadth caused Cell Clusters complexes cross-neutralize Defense defined Delta determinant determinants determine disease driven by Efficacy escape Fab FIVE greater highest Host host defense identifying Immune escape immune protection Infection initial memory B memory B cell Mitigation Mutation neutralization neutralization potency neutralize neutralized Neutralizing activity Neutralizing antibodies neutralizing antibody omicron Prevalence RBD real-world data Receptor binding domain recognize recognizing Region SARS-CoV-2 SARS-CoV-2 spike glycoprotein SARS-CoV-2 strain sensitivity Specificities specificity spike glycoprotein Spike receptor binding domain Structure structures tested the RBD the SARS-CoV-2 Vaccine vaccine efficacy variant variants variants of concern Viral viral escape viral invasion Wuhan strain
[DOI] 10.1126/sciimmunol.abo3425 PMC 바로가기 [Article Type] Article

ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies

ACE2 결합은 코로나바이러스 항체를 광범위하게 중화시키는 SARS-CoV-2 융합 펩타이드를 노출시킵니다

Article

Published on 2022-08-122022-09-11
Journal: Science (New York, N.y.) [Category] COVID19(2023년), MERS, SARS, 비임상, 진단,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity Alpha alpha- Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 animal coronavirus Animal coronaviruses antibody approach betacoronaviruses binding breadth breath conserved coronavirus coronavirus spike protein donors enzyme epitope functional fusion peptide hidden host receptor Host receptors immune in vitro in vivo mAb mAbs monoclonal antibodies monoclonal antibody motif neutralize Neutralizing Neutralizing activity omicron pathology peptide prefusion recognize reduce respiratory SARS-CoV-2 selected Seven severe acute respiratory syndrome Coronavirus somatic mutations spike glycoprotein Spike proteins the SARS-CoV-2 Viral viral burden virus viruses
[DOI] 10.1126/science.abq2679 PMC 바로가기 [Article Type] Article

Display of receptor-binding domain of SARS-CoV-2 Spike protein variants on the Saccharomyces cerevisiae cell surface

Article

Published on 2022-08-122022-11-15
Journal: Frontiers in Immunology [Category] SARS, 변종, 진단,