Remote diagnosis of surgical-site infection using a mobile digital intervention: a randomised controlled trial in emergency surgery patientsArticle Published on 2021-11-182022-10-04 Journal: NPJ Digital Medicine [Category] 임상, [키워드] 1:1 abdominal surgery Care Community Control Diagnosis facilitate feasible Follow-up healthcare service higher odd hospital Infection Infectious diseases Intervention morbidity no significant difference Outcomes research Patient postoperative Primary outcome randomised randomised controlled trial receiving reduced remote required routine care significantly surgical site Symptom tertiary care hospitals Treatment Trial [DOI] 10.1038/s41746-021-00526-0 PMC 바로가기 [Article Type] Article
Burdens of post-acute sequelae of COVID-19 by severity of acute infection, demographics and health statusArticle Published on 2021-11-122022-10-04 Journal: Nature Communications [Category] MERS, SARS, 치료법, [키워드] acute infection Affair age baseline build burden Care caused Cohort Control COVID-19 database demographic group demographics Department differentially expressed Epidemiology groups Health Health status health system healthcare non-infected Outcomes research PASC people with COVID-19 risk factor SARS-CoV-2 SARS-COV-2 infection severity Sex Variation veteran viral infection [DOI] 10.1038/s41467-021-26513-3 PMC 바로가기 [Article Type] Article
SARS-CoV-2 immunity and functional recovery of COVID-19 patients 1-year after infectionSARS-CoV-2 감염 1년 후 COVID-19 환자의 면역 및 기능 회복Clinical Trial Published on 2021-10-132022-09-10 Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 변종, 임상, 진단, 치료기술, 치료제, [키워드] 95% CI Adaptive immunity analyzed Anti-RBD IgG anti-receptor-binding domain antibody B.1.1.7 B.1.351 B.1.351 variant B.1.351 variants chemiluminescence chemiluminescence immunoassay Chest CT China consequence COVID-19 COVID-19 patient COVID-19-related symptoms detectable Diagnosis discharge estimate functional General population highlight immune immune protection Immunity implication Infection Infectious diseases life long-lasting neutralization non-severe patient Outcomes research participant Patient Predictive preventive measure preventive measures prospective cohort Pulmonary function Quality of life RBD Re-infection recovered COVID-19 patient reduced remained reported risk SARS-CoV-2 immunity SARS-COV-2 infection Seroprevalence Severe patient severe patients significantly Survivors symptomatic Total variant WT SARS-CoV-2 [DOI] 10.1038/s41392-021-00777-z PMC 바로가기 [Article Type] Clinical Trial
Tocilizumab reduces COVID-19 mortality and pathology in a dose and timing-dependent fashion: a multi-centric study토 실리 주맙Article Published on 2021-10-052022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료법, [키워드] Administered appear cornerstone COVID-19 COVID-19 mortality Critical cytokine Cytokine storm dose doses drug IL-6 Inflammation Inflammatory Inflammatory marker inflammatory markers marker moderate Molecularly targeted therapy Mortality outcomes Outcomes research pathology pathway Patient patients patients with moderate performed post-symptom onset Prevent progression reduce reduced respiratory Respiratory Support retrospective Severity of disease shown significantly Stage stages Standard dose the stage Tocilizumab treated patients Variation variations Viral viral infection were measured [DOI] 10.1038/s41598-021-99291-z PMC 바로가기 [Article Type] Article
Budget constrained machine learning for early prediction of adverse outcomes for COVID-19 patientsArticle Published on 2021-10-012022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, [키워드] adverse outcome Analysis approach budget clinical evaluation clinical utility cohort study Combination Computational science COVID-19 patient data-driven Deterioration develop EHR EHR data Electronic health record evaluate example hospitalized COVID-19 patient IMPROVE Infection Laboratory tests ML model Mortality outcome Outcomes research Patient patients with SARS-CoV-2 performed Predictive ProMedica reduction in resource risk risk stratification tested Ventilation ventilatory support was performed [DOI] 10.1038/s41598-021-98071-z PMC 바로가기 [Article Type] Article
Is glucose-6-phosphatase dehydrogenase deficiency associated with severe outcomes in hospitalized COVID-19 patients?Article Published on 2021-09-282022-10-04 Journal: Scientific Reports [Category] SARS, 치료법, [키워드] 95% confidence interval age aggravate antioxidant association COVID-19 patients deficiency Epidemiology glucose-6-phosphate dehydrogenase deficiency Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient Intervention intubation likelihood non-invasive ventilation not significantly different Occurrence outcome Outcomes research Patient presence of comorbidity Research Respiratory signs and symptoms Risk factors severe COVID-19 severity of COVID-19 suppress viral infection [DOI] 10.1038/s41598-021-98712-3 PMC 바로가기 [Article Type] Article
Comparison of the impact of chronic corticosteroid therapy on critical care outcomes of COVID-19 patients with and without history of chronic liver diseaseArticle Published on 2021-09-282022-10-04 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] 28-day mortality Analysis chronic liver disease CLD comorbid condition condition conducted Corticosteroid corticosteroid therapy COVID-19 COVID-19 hospitalization COVID-19 pandemic COVID-19 patient COVID-19 severity Critical care daily dose demonstrated dose group Hospital stay Hospitalization Hospitalized ICU ICU admission inclusion criteria information liver Mortality no difference outcome Outcomes research Patient patients with COVID-19 retrospective risk factor Risk factors secondary seeking statistically significant difference viral infection with COVID-19 [DOI] 10.1038/s41598-021-98778-z PMC 바로가기 [Article Type] Article
Impact of overlapping risks of type 2 diabetes and obesity on coronavirus disease severity in the United StatesArticle Published on 2021-09-092022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] age analysed cohort study Complication complications conducted coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19 patients COVID-19 severity Critical care diabete diabetes Diabetes complications evaluate hazard ratio Hospitalization Impact male Male sex medication metabolic syndrome obesity outcomes Outcomes research overlapping Participants Patient risk risk factor Risk factors risk score Risk scores severity Sex significantly T2D the United State type 2 diabete with COVID-19 [DOI] 10.1038/s41598-021-96720-x PMC 바로가기 [Article Type] Article
Ascorbic acid as an adjunctive therapy in critically ill patients with COVID-19: a propensity score matched studyClinical Trial Published on 2021-09-032022-10-04 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 치료법, [키워드] 30-Day mortality 95% CI administration admitted to ICU Analysis ascorbic acid association baseline Clinical efficacy Clinical outcome clinician conducted COVID-19 COVID-19 diagnosis COVID-19 pandemic Critically ill Critically ill patient dose Efficacy and safety evaluate Final hospital in-hospital mortality incidence Infectious diseases Mortality Outcomes research Patient propensity score matching required retrospective cohort study Saudi Arabia severity scores therapy thrombosis use of corticosteroids with COVID-19 [DOI] 10.1038/s41598-021-96703-y PMC 바로가기 [Article Type] Clinical Trial
Risk-factors for re-admission and outcome of patients hospitalized with confirmed COVID-19Article Published on 2021-08-312022-10-04 Journal: Scientific Reports [Category] MERS, 바이오마커, [키워드] 95% CI 95% confidence interval age Analysis baseline burden cognitive Comorbidities Comorbidity COVID-19 COVID-19 severity died discharge discharged Epidemiology Factor globe hazard ratio help hospitalized COVID-19 hospitalized COVID-19 patient hospitalized patients identify Implications interquartile range median moderate Mortality Multivariate analysis outcome Outcomes research Patient patients hospitalized performed Retrospective study risk factor SARS-CoV-2 solid organ transplantation Treatment [DOI] 10.1038/s41598-021-96716-7 PMC 바로가기 [Article Type] Article