Detection of high frequency of MAD20 allelic variants of Plasmodium falciparum merozoite surface protein 1 gene from Adama and its surroundings, Oromia, Ethiopia아다마 및 그 주변 지역인 오로미아, 에티오피아에서 Plasmodium falciparum 메로조이트 표면 단백질 1 유전자의 MAD20 대립변이의 높은 빈도 탐지Research Published on 2021-09-272024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] Genetic polymorphism Msp-1 multiplicity of infection P. falciparum [DOI] 10.1186/s12936-021-03914-9 PMC 바로가기 [Article Type] Research
Transcriptome-based analysis of blood samples reveals elevation of DNA damage response, neutrophil degranulation, cancer and neurodegenerative pathways in Plasmodium falciparum patients혈액 샘플의 전사체 기반 분석은 말라리아 원충 감염 환자에서 DNA 손상 반응, 호중구 탈과립, 암 및 신경퇴행성 경로의 증가를 밝혀냅니다.Research Published on 2021-09-262024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] Axonal dysfunction cellular stress cerebral malaria immune response neutrophil degranulation P. falciparum [DOI] 10.1186/s12936-021-03918-5 PMC 바로가기 [Article Type] Research
Common host variation drives malaria parasite fitness in healthy human red cells일반적인 숙주 변이가 건강한 인간 적혈구에서 말라리아 기생충의 적합성을 증가시킨다.Article Published on 2021-09-232024-08-08 Journal: eLife [Category] 말라리아, [키워드] Human malaria natural variation P. falciparum parasite fitness Plasmodium falciparum red blood cells [DOI] 10.7554/eLife.69808 PMC 바로가기
Longitudinal trends in malaria testing rates in the face of elimination in eastern Myanmar: a 7-year observational study동부 미얀마에서 말라리아 퇴치를 위한 검사 비율의 종단적 추세: 7년 관찰 연구Research Article Published on 2021-09-222024-08-08 Journal: BMC Public Health [Category] 말라리아, [키워드] Community health worker Elimination Integrated health services malaria P. falciparum P. vivax RDT testing rate [DOI] 10.1186/s12889-021-11749-x PMC 바로가기 [Article Type] Research Article
The role of upstream open reading frames in translation regulation in the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii아피콤플렉사 계열 기생충인 말라리아 원충(Plasmodium falciparum)과 톡소포자충(Toxoplasma gondii)에서 번역 조절에 있어 상류 개방 읽기 프레임의 역할Review Article Published on 2021-09-082024-08-08 Journal: Parasitology [Category] 말라리아, [키워드] P. falciparum T. gondii translational regulation upstream ORFs [DOI] 10.1017/S0031182021000937 PMC 바로가기 [Article Type] Review Article
Antiplasmodial activity of the natural product compounds alstonine and himbelinearticle Published on 2021-08-312024-09-01 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] Alstonine Chemoprevention Drug discovery Himbeline natural products P. falciparum [Article Type] article
Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparumarticle Published on 2021-08-312024-09-01 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] drug resistance Functional genomics iSAFE P. falciparum [Article Type] article
Limited polymorphism in k13 gene of Plasmodium falciparum and k12 of Plasmodium vivax isolates imported from African and Asian countries between 2014 and 2019 in Hangzhou city, China2014년과 2019년 사이에 중국 항저우시에서 아프리카 및 아시아 국가에서 수입된 Plasmodium falciparum의 k13 유전자와 Plasmodium vivax의 k12 유전자에서 제한된 다형성.Research Published on 2021-08-212024-08-08 Journal: BMC Infectious Diseases [Category] 말라리아, [키워드] K13 P. falciparum P. vivax polymorphism [DOI] 10.1186/s12879-021-06579-6 PMC 바로가기 [Article Type] Research
A genetic intervention유전적 개입Article Published on 2021-08-122024-08-08 Journal: eLife [Category] 말라리아, [키워드] Asia drug resistance genetic surveillance malaria P. falciparum [DOI] 10.7554/eLife.72000 PMC 바로가기
NICEdrug.ch, a workflow for rational drug design and systems-level analysis of drug metabolismTools and Resources Published on 2021-08-032022-10-31 Journal: eLife [Category] COVID-19, [키워드] alleviate Analysis anticancer candidate drug Cell COVID-19 database dataset drug drug clustering drug design drug metabolic fate drug similarity E. coli enzyme Enzyme inhibition evaluate explain golden standard high risk Human human host identify include inhibitory Intensive ligand-based drug discovery malaria mechanism metabolism metabolite nutraceuticals P. falciparum reactive reactivity reduce Research resource Side effects similarity small molecule targets toxicities Toxicity unique [DOI] 10.7554/eLife.65543 PMC 바로가기 [Article Type] Tools and Resources