Brief comparative evaluation of six open one-step RT-qPCR mastermixes for the detection of SARS-CoV-2 RNA using a Taqman probeTaqman 프로브를 사용한 SARS-CoV-2 RNA 검출을 위한 6개의 개방형 1단계 RT-qPCR 마스터믹스에 대한 간략한 비교 평가Comparative Study Published on 2020-11-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 치료기술, 치료제, [키워드] (Promega) (RdRp ABI 7500 acute respiratory syndrome coronavirus Applied Biosystems clinical laboratories Concordance coronavirus coronavirus 2 Ct value Ct values emerging virus exhibiting FIVE France Invitrogen Laboratory Laboratory-developed assay master mix New England Biolabs open pandemic percentage percentages Promega qPCR qRT-PCR RdRP reagent reagents reference respiratory respiratory specimen respiratory specimens RNA RNA polymerase RNA virus Roche RT-PCR kit RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shortage of reagent step System Takara TaqMan TaqMan probe thermocycler Universal Viral Viral RNA was tested [DOI] 10.1016/j.jcv.2020.104636 PMC 바로가기 [Article Type] Comparative Study
Continuing surgical care in cancer patients during the nationwide lockdown in the COVID-19 pandemic-Perioperative outcomes from a tertiary care cancer center in IndiaObservational Study Published on 2020-11-012022-10-05 Journal: Journal of surgical oncology [Category] SARS, 임상, [키워드] Analysis asymptomatic patient Cancer Cancer center cancer patient cancer surgery cancers Care categorical variable classification Continuous coronavirus COVID COVID-19 Frequency Hospital staff illnesses imperative India initiated Intervention lockdown management median morbidity Mortality Non-COVID-19 organ outcome outcomes over pandemic patients percentages perioperative outcomes. precautions required statistically significant study period surgical symptomatic symptomatic patient Treatment two-sided α undergo were expressed [DOI] 10.1002/jso.26134 PMC 바로가기 [Article Type] Observational Study
Epidemiological Characteristics and Clinical Outcomes of Coronavirus Disease Patients in Northwest China: High-Volume Research From Low Population Density RegionsMedicine Published on 2020-10-302022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 1:1 acute respiratory syndrome age Analysis analyzed average calculated carrier Characteristics children China city clinical Clinical outcome contagiousness coronavirus coronavirus disease correlated COVID-19 COVID-19 patient density diagnosed discharge disease course enrolled epidemiological Epidemiological characteristics healthy Hospitalization Infants Infection low density population low-density male median median age morbidity morbidity and mortality National Novel coronavirus outcomes Patient patients percentages Pneumonia Population populations positive result positive test result pregnant Public health intervention Region reported representing responsible SARS-CoV-2 severity significantly susceptible Symptom the epidemic Transmission Two patient variable Wuhan [DOI] 10.3389/fmed.2020.564250 PMC 바로가기 [Article Type] Medicine
Kawasaki Disease-Like Features in 10 Pediatric COVID-19 Cases: A Retrospective StudyInternal Medicine Published on 2020-10-192022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Admission assist caused change children Complete complications conjunctival coronavirus coronavirus disease COVID-19 COVID-19 infection Critical care database diagnosed with COVID-19 feature Features FIVE help Hospital stay Infection Inflammatory inflammatory illness Kawasaki disease Laboratory less management median age Mild mimicking Mortality observation occurred outcomes Patient patients pediatric Pediatric case Pediatric patients percentages Rash required respiratory tract infection SARS-CoV-2 searched Symptom Treatment treatment strategy upper respiratory tract [DOI] 10.7759/cureus.11035 PMC 바로가기 [Article Type] Internal Medicine
Elevated Exhaustion Levels of NK and CD8 + T Cells as Indicators for Progression and Prognosis of COVID-19 DiseaseCOVID-19 질병의 진행 및 예후 지표로서의 NK 및 CD8 + T 세포의 고갈 수준 증가Immunology Published on 2020-10-142022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 치료기술, [키워드] (PD-1) acute respiratory syndrome coronavirus analyzed association Blood CD16 CD244 CD3 CD4 CD56 CD8 Cell cell population Characteristics circulating Clinical data collected contribute coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 patient Critical Critical illness cytokine Cytokines demographic disease disease severity dysregulation effector molecule elevated eliminating enrolled evaluated Exhaustion expression flow cytometry functional IL-10 IL-6 immune dysregulation immune system IMPROVE Indicator infected cells Level Logistic regression logistic regression model lymphocyte Lymphocyte subset Lymphocyte subsets natural killer natural killer (NK) cells NK cell NK cells NKT cell NKT cells Pathogenesis Patient patients with COVID-19 PD-1 percentage percentages perforin phenotypic predict Prognosis progression public health reduced Regulatory respiratory Result risk factor Risk factors SARS-CoV-2 screened serum Serum IL-6 Serum level serum levels severe acute respiratory syndrome coronavirus 2 Severe case severe cases severe COVID-19 patients severe patients severe symptoms severity of COVID-19 significantly significantly increased subset T cell T cells TNF-α Union Hospital virus Wuhan [DOI] 10.3389/fimmu.2020.580237 PMC 바로가기 [Article Type] Immunology
A Countrywide Survey in Saudi Arabia Regarding the Knowledge and Attitude of Health Care Professionals about Coronavirus Disease (COVID-19)Article Published on 2020-10-122022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] 2019-nCoV adjusted odds ratio analyzed Attitude Care conducted coronavirus prevention COVID-19 cross-sectional diploma disease domain FIVE geographical region groups hcp Health health care professionals help higher risk independent variable infection control information Kingdom knowledge Ministry of Health multivariate logistic regression nomenclature Odds ratio pandemic percentages positive attitude Preparedness planning professional Qualtrics question questionnaire Region SARS-CoV2 Saudi Arabia SPSS statistical survey variable was performed website [DOI] 10.3390/ijerph17207415 PMC 바로가기 [Article Type] Article
Consequences of the COVID-19 pandemic on the continuum of care in a cohort of people living with HIV followed in a single center of Northern ItalyResearch Published on 2020-10-042022-10-27 Journal: AIDS Research and Therapy [Category] [키워드] adherence age antiretroviral drug ART average bimester Brescia Care categorical variable Cohort consequence continuous variable continuum COVID-19 COVID-19 pandemic COVID19 described Diagnosis Efficacy female Follow-up Frequency Healthcare system highlight HIV HIV continuum of care HIV patient hospital Hospitalization Hospitalized interquartile range IQR Italy Mann–Whitney test median Patient percentages performed PLWH Protease inhibitor public health raise reduction in regimen Result retrieved retrospective SARS-CoV-2 single center Student’s t-test with HIV [DOI] 10.1186/s12981-020-00314-y PMC 바로가기 [Article Type] Research
Consequences of the COVID-19 pandemic on the continuum of care in a cohort of people living with HIV followed in a single center of Northern ItalyResearch Published on 2020-10-042022-10-27 Journal: AIDS Research and Therapy [Category] COVID-19, MERS, SARS, [키워드] adherence age antiretroviral drug ART average bimester Brescia Care categorical variable Cohort consequence continuous variable continuum COVID-19 COVID-19 pandemic COVID19 described Diagnosis Efficacy female Follow-up Frequency Healthcare system highlight HIV HIV continuum of care HIV patient hospital Hospitalization Hospitalized interquartile range IQR Italy Mann–Whitney test median Patient percentages performed PLWH Protease inhibitor public health raise reduction in regimen Result retrieved retrospective SARS-CoV-2 single center Student’s t-test with HIV [DOI] 10.1186/s12981-020-00314-y PMC 바로가기 [Article Type] Research
Computational analysis of SARS-CoV-2, SARS-CoV, and MERS-CoV genome using MEGAOriginal Article Published on 2020-09-242022-11-01 Journal: Genomics & Informatics [Category] COVID-19, [키워드] acute respiratory syndrome Analysis average base Bayesian information criterion BIC Biotechnology center China coronavirus criterion Frequency Genetic Genetic variation genomic data highlight information likelihood lowest MERS-CoV MERS-CoV genome Middle East Middle East respiratory syndrome Molecular Evolutionary Genetic Analysis National Center for Biotechnology Information NCBI Novel coronavirus nucleotide nucleotide substitution pandemic percentages respiratory syndrome coronavirus SARS-CoV SARS-CoV-2 Spread statistical analysis used to evaluate [DOI] 10.5808/GI.2020.18.3.e30 PMC 바로가기 [Article Type] Original Article
Association of Public Interest in Preventive Measures and Increased COVID-19 Cases After the Expiration of Stay-at-Home Orders: A Cross-Sectional StudyBrief Report Published on 2020-09-102022-10-31 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] association average Bivariate correlation changes in confirmed case confirmed COVID-19 case coronavirus disease COVID-19 COVID-19 case death expiration expired fatality Google Increased increases in interest less measure negative correlation percentages preventive measure preventive measures proportion Public Public awareness public preparedness search trends trend Volume was collected [DOI] 10.1017/dmp.2020.333 PMC 바로가기 [Article Type] Brief Report