Coagulation parameters predict COVID-19-related thrombosis in a neural network with a positive predictive value of 98Article Published on 2022-09-282022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] age C-reactive protein changes in clinical complication coagulation factor Coagulation system Cohort complexes complicate COVID-19 COVID-19 infection COVID-19 patient hospital Hospital admission ICU admission IgM Laboratory multifactorial neural net Neural network parameter pathogenesis of COVID-19 Patient patients Positive predictive value predict prediction serum Sex suffered thrombin Thrombin generation thrombosis thrombotic event variable [DOI] 10.3389/fimmu.2022.977443 PMC 바로가기
Usefulness of KL-6 for Predicting Clinical Outcomes in Hospitalized COVID-19 PatientsArticle Published on 2022-09-212022-11-15 Journal: Medicina [Category] 바이오마커, [키워드] 30-Day mortality 95% confidence interval acute lung injury Admission age Analysis analyzed automated Biomarker CCI characteristic clinical Clinical outcome clinical outcomes Comorbidity contribute coronavirus disease COVID-19 COVID-19 patient Critical care Critical disease demonstrated ECMO extracorporeal membrane oxygenation hazard ratio Hospitalized hospitalized COVID-19 patients ICU admission initial intensive care Interstitial lung disease Japan Kaplan-Meier method Kaplan-Meier survival analysis KL-6 Kobe outcome patients predict predicted prediction quartile reflect Result ROC ROC Curve significantly ventilator were measured [DOI] 10.3390/medicina58101317 PMC 바로가기
VOC-DL: Deep learning prediction model for COVID-19 based on VOC virus variantsVOC-DL: VOC 바이러스 변종 기반 코로나19 딥 러닝 예측 모델Article Published on 2022-09-012022-09-11 Journal: Computer methods and programs in biomedicine [Category] 변종, [키워드] Accuracy affected analyzed average concern confirmed case confirmed cases country COVID-19 dataset datasets deep deep learning develop experimental results FIVE framework highest India information Italy Japan long term LSTM medium other variant other variants pandemic predict prediction Predictive Region robustness Russia South Korea stability time Time series Transmission variant variants virus variant virus variants VoC VOC-DL model [DOI] 10.1016/j.cmpb.2022.106981 PMC 바로가기 [Article Type] Article
Modified SIR model for COVID-19 transmission dynamics: Simulation with case study of UK, US and IndiaResearch article Published on 2022-09-012022-10-05 Journal: Results in Physics [Category] 변종, [키워드] Accuracy Analysis analyzed Asymptomatic average Characteristics classical compartmental model contributed Corona virus country COVID-19 COVID-19 transmission death demographical factor disease disease spread epidemiological Factor Factors global public health India Infection infection rate Infectious disease mortality rate outbreak pandemic Patient patients performance predict prediction provide quarantine R-Square score Rate Seven Simulation SIR model Spread statistical model the disease Transmission variants [DOI] 10.1016/j.rinp.2022.105855 [Article Type] Research article
Predicting malaria outbreaks from sea surface temperature variability up to 9 months ahead in Limpopo, South Africa, using machine learningarticle Published on 2022-08-312024-09-01 Journal: Frontiers in public health [Category] 말라리아, [키워드] Climate machine learning malaria prediction South Africa weather [Article Type] article
Facilitating Safe Discharge Through Predicting Disease Progression in Moderate Coronavirus Disease 2019 (COVID-19): A Prospective Cohort Study to Develop and Validate a Clinical Prediction Model in Resource-Limited SettingsClinical Trial Published on 2022-08-242022-10-04 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, [키워드] acute respiratory syndrome age biochemical Biomarker C-reactive protein clinical clinical parameter clinical utility clinician Cohort coronavirus coronavirus disease COVID-19 D-dimer death defined demonstrated develop evaluated expressed external validation Facilitating greater health system help hospital identify IL-6 India infections laboratory-confirmed LMIC low- and middle-income country management Model moderate Neutrophil-to-lymphocyte ratio NLR participant Patient patients with moderate prediction presenting Primary outcome procalcitonin prognostic prognostic model progression Prospective provided Rapid test receptor recruited resources respiratory rate SARS-CoV-2 setting Sex soluble Triggering Receptor SpO2 SpO2/FiO2 suPAR supplemental oxygen Symptom Triage utility Vaccines validation cohort [DOI] 10.1093/cid/ciac224 PMC 바로가기 [Article Type] Clinical Trial
Prediction of Potential Commercially Available Inhibitors against SARS-CoV-2 by Multi-Task Deep Learning Model다중 작업 딥 러닝 모델을 통한 SARS-CoV-2에 대한 잠재적으로 상업적으로 이용 가능한 억제제 예측Article Published on 2022-08-212022-09-11 Journal: Biomolecules [Category] SARS, 치료제, [키워드] binding binding mode binding modes can be used caused Compound COVID-19 dataset datasets death deep deep learning drug Drug discovery effective effective drug effective drugs effective inhibitor effort exhibited fine-tune help heterogenous identify Infection inhibitors Interaction learning Model molecular docking multi-task learning outbreak performed Potential predicted prediction Prevent protein-ligand interaction protein–ligand interaction. rising SARS-CoV-2 SARS-CoV-2 protein selected severe symptoms targets was collected was used [DOI] 10.3390/biom12081156 PMC 바로가기 [Article Type] Article
Reliability of predictive models to support early decision making in the emergency department for patients with confirmed diagnosis of COVID-19: the Pescara Covid Hospital scoreCOVID-19 진단이 확인된 환자의 응급실에서 조기 의사 결정을 지원하는 예측 모델의 신뢰성: Pescara Covid Hospital 점수Article Published on 2022-08-192022-09-11 Journal: BMC health services research [Category] 변종, [키워드] Abruzzo Accuracy Admission age and gender Algorithm Alpha build calibrated can be used carried Characteristics clinical decision collecting data conditions COVID-19 D-dimer death decision Decision making diabete diabetes diagnosed with COVID-19 Diagnosis disease distribution emergency department heterogeneous higher risk hospital hospital management hospitalisation identify independent predictor independent predictors initial intensive care Italy laboratory parameter Laboratory parameters Lactate lactate dehydrogenase Logistic regression monocyte other variant other variants outcome oxygen oxygen support pandemic parameter Patient patients with COVID-19 prediction Prediction score Predictive model predictive models predictor procalcitonin Prognosis renal renal disease Retrospective study risk Risk scores risk stratification saturation significantly Support survival threshold validation variants of concern virus were used [DOI] 10.1186/s12913-022-08421-4 PMC 바로가기 [Article Type] Article
Antibody therapy reverses biological signatures of COVID-19 progression항체 요법은 COVID-19 진행의 생물학적 특징을 역전시킵니다.Randomized Controlled Trial Published on 2022-08-162022-09-11 Journal: Cell Reports Medicine [Category] SARS, 바이오마커, 임상, 진단, 치료기술, [키워드] 1:1 Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody therapy antibody treatment Biomarkers clinical decision clinical trial coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression Decision making decrease Disease progression disease severity e parameters effective facilitate greater Hospitalized identify Infection Laboratory parameters lymphocyte marker monoclonal antibody Nasopharyngeal samples neutrophil Neutrophil-to-lymphocyte ratio NLR normalization occur parameter participant Placebo prediction Predictive profiles progression provide Randomized respiratory risk risk for disease SARS-CoV-2 serologic test severe acute respiratory syndrome Coronavirus severe coronavirus disease severe disease Sotrovimab study participant Study participants Transcriptome transcriptomic profile transcriptomics Treatment understanding Viral Viral RNA [DOI] 10.1016/j.xcrm.2022.100721 PMC 바로가기 [Article Type] Randomized Controlled Trial
Chemerin plasma levels are increased in COVID-19 patients and are an independent risk factor of mortalityArticle Published on 2022-08-122022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] activity acute respiratory distress Admission Analysis analyzed anti-inflammatory property ARDS Belgium Biomarker blood cell blood sample C-reactive protein chemerin chemotactic ChemR23 Clinical practice CMKLR1 collected Concentration correlated COVID-19 COVID-19 patient COVID-19 patients death Deceased demonstrated disease evaluate evaluated expression Extracellular flow cytometry healthy control ICU ICU patient identify IHC immunohistochemistry Increased independent risk factor Inflammatory biomarker inflammatory conditions intensive care Lung pathology lung tissue marker mechanism Mortality Necrosis Patient plasma predict prediction Prognostic value Protein severity significantly higher smooth muscle cell subtype survival survivor syndrome Viral pneumonia [DOI] 10.3389/fimmu.2022.941663 PMC 바로가기