Genomic surveillance of SARS-CoV-2 in Puerto Rico enabled early detection and tracking of variants Research Published on 2022-08-112022-10-05 Journal: Communications Medicine [Category] 변종, 치료기술, [키워드] agency Analysis approach cause circulation competing conducted COVID-19 COVID-19 case COVID-19 pandemic Critical Epidemic event genomic Genomic surveillance Health highlight Lineage Local Molecular epidemiology phylogenetic inference predominant public health Public health responses replaced Result SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomic surveillance SARS-CoV-2 variant sequenced Spread spread to study period Surveillance The United States variant virus [DOI] 10.1038/s43856-022-00168-7 [Article Type] Research
SARS-CoV-2 infection risk among vaccinated and unvaccinated household members during the Alpha variant surge – Denver, Colorado, and San Diego, California, January-April 2021알파 변종 급증 시 백신 접종 및 미접종 가구 구성원 간의 SARS-CoV-2 감염 위험 - 콜로라도주 덴버 및 캘리포니아주 샌디에이고, 2021년 1월-4월Article Published on 2022-08-052022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Alpha Alpha variant antibody Asymptomatic B.1.1.7 Blood collected Community conducted confidence confidence interval Contact COVID-19 COVID-19 vaccination Culture Cycle threshold values Diego Effectiveness eligible enrolled Epsilon Evidence examined highlight household household contact household contacts household transmission Households incidence individual infection risk infection risks information interval Lineage nasopharyngeal swabs predominant proportion protective effect reduce reported risk RT-PCR SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 variant secondary case secondary cases Support symptomatic Transmission vaccination vaccine effectiveness variant variants [DOI] 10.1016/j.vaccine.2022.06.066 PMC 바로가기 [Article Type] Article
Relative effectiveness of booster vs. 2-dose mRNA Covid-19 vaccination in the Veterans Health Administration: Self-controlled risk interval analysis재향 군인 보건국에서 부스터 대 2-용량 mRNA 코비드-19 백신 접종의 상대적 효과: 자가 통제 위험 간격 분석Article Published on 2022-08-052022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] (Maximum 6): Covid-19 age Analysis Antigen approach booster booster vaccination calculate calculated conducted confounders Delta effective Effectiveness exposure Gain groups health administration identify Immunity individual Logistic regression main analysis maximum mRNA odds of infection Odds ratio Odds ratios omicron Omicron variants positive positive PCR Positive test predominant relative risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test Self-controlled case series Sensitivity analyses sensitivity analysis Stratification Study design vaccination Vaccine vaccine effectiveness variant veteran warehouse [DOI] 10.1016/j.vaccine.2022.06.047 PMC 바로가기 [Article Type] Article
Interim Recommendation of the Advisory Committee on Immunization Practices for Use of the Novavax COVID-19 Vaccine in Persons Aged ≥18 years – United States, July 202218세 이상인 사람의 Novavax COVID-19 백신 사용에 대한 예방접종 관행에 대한 자문 위원회의 임시 권고 - 미국, 2022년 7월Article Published on 2022-08-052022-09-11 Journal: Morbidity and Mortality Weekly Report [Category] SARS, 변종, [키워드] 95% CI Administered Adults Alpha variant assessments association authorization B.1.1.7 causal relationship cause Chain Reaction circulating Committee COVID-19 COVID-19 vaccine dose drug Efficacy efficacy analysis Emergency Emergency use authorization EUA FDA flexibility food Food and Drug Administration immunization infection with SARS-CoV-2 information Interim Matrix-M myocarditis Novavax NVX-CoV2373 per-protocol Pericarditis Person polymerase chain reaction Practice predominant PROTECT Protein provide reported reverse transcription Reverse transcription-polymerase chain reaction RT-PCR SARS-CoV-2 symptomatic symptomatic COVID-19 United States vaccination Vaccine vaccine efficacy variant virus [DOI] 10.15585/mmwr.mm7131a2 PMC 바로가기 [Article Type] Article
Genomic epidemiology of the first two waves of SARS-CoV-2 in Canada캐나다 SARS-CoV-2의 첫 두 파동의 게놈 역학Article Published on 2022-08-022022-09-11 Journal: eLife [Category] SARS, 변종, 유전자 메커니즘, 진단, [키워드] 95% confidence interval B.1.1.7 Canada circulating contributed COVID-19 COVID-19 case COVID-19 cases Critical declined descendants drastic reduction Effectiveness Epidemiology Evolutionary biology First wave Genomics global health highlighting implementation in viral increasingly India International Intervention introduced investigated likelihood lineages maximum molecular Molecular epidemiology National outbreak persistence Phylogenetic tree phylogenetics predominant Prevalence public health Public health interventions reduce reducing resulting SARS-CoV-2 SARS-CoV-2 lineage second wave Spread summer sustained the timing Transmission Travel USA variant variants of concern Viral virus viruses VOCs were used [DOI] 10.7554/eLife.73896 PMC 바로가기 [Article Type] Article
Single-cell RNA sequencing to decipher the immunogenicity of ChAdOx1 nCoV-19/AZD1222 and mRNA-1273 vaccines in patients with autoimmune rheumatic diseases자가면역 류마티스 질환 환자에서 ChAdOx1 nCoV-19/AZD1222 및 mRNA-1273 백신의 면역원성을 해독하기 위한 단일 세포 RNA 시퀀싱Article Published on 2022-08-012022-09-12 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] Analysis analyzed anti-rheumatic medications anti-SARS-CoV-2 IgG antibodies Antigen presentation Arthritis Autoimmune AZD1222 CD16 CD4 ChAdOx1 COVID-19 COVID-19 vaccine database domain dose electrochemiluminescence immunoassay enriched pathway enrolled exhibited Gene Expression Omnibus GEO healthy controls HLA-DRA immunized inhibitor Interaction Janus kinase methotrexate MHC class Moderna monocyte mononuclear cell mRNA-1273 mRNA-1273 vaccine mRNA-based vaccine Necrosis Oxford-AstraZeneca participant pathway Patient patients PBMC PBMCs Peripheral blood predominant quantified receiving rheumatic disease RNA sequencing scRNA-seq serum IgG antibody Single-cell RNA sequencing the SARS-CoV-2 vaccination Vaccine [DOI] 10.3389/fimmu.2022.920865 PMC 바로가기 [Article Type] Article
Comparison of Severe Maternal Morbidities Associated With Delivery During Periods of Circulation of Specific SARS-CoV-2 Variants특정 SARS-CoV-2 변이체의 순환 기간 동안 분만과 관련된 심각한 산모 이환율의 비교Multicenter Study Published on 2022-08-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] age Alpha Alpha variant amplification analyzed association B.1.1.7 B.1.617.2 cause center characterized clinical variable cohort study complications Control COVID-19 defined delivery Delta delta variant demographic and clinical variables disease control dominant evaluate event events Evidence evidence of example health system highest Hospitalization individual Infection IQR Maternal median morbidity multicenter nucleic acid nucleic acid amplification test Odds ratio omicron outcome outcomes over pandemic Patient patients with SARS-CoV-2 Period predominant pregnant patient pregnant patients prevention preventive measures Primary outcome reflected Respiratory complications retrospective cohort study risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleic acid secondary Secondary outcomes severity of COVID-19 significantly higher Specific Strains test result the SARS-CoV-2 type strain Variation viral strain viral strains was increased while wild-type strain [DOI] 10.1001/jamanetworkopen.2022.26436 PMC 바로가기 [Article Type] Multicenter Study
Clinical and genomic signatures of SARS-CoV-2 Delta breakthrough infections in New York뉴욕에서 SARS-CoV-2 Delta 획기적인 감염의 임상 및 게놈 서명Article Published on 2022-08-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] adaptive age Alpha Analysis Breakthrough infection breakthrough infections center circulating variant circulating variants clinical clinical variables confounders contributed controls COVID-19 hospitalization death Delta determinant distribution Epidemic Genome genomic Genomic signatures of vaccine breakthrough growth Hospitalization increasingly individuals Infection Isaac Mutation network network analysis Network analysis of clinical variables New York Nsp12 occurred parameters Phylogenetic predominant prevented profiles SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variant of concern (VOC) delta Selective adaptation significantly spike spike mutation Spike S112L and nsp12 F192V Support supported technology time Time since vaccination. vaccination Vaccine vaccine breakthrough infection vaccine breakthrough infections viruses VoC while [DOI] 10.1016/j.ebiom.2022.104141 PMC 바로가기 [Article Type] Article
Cognitive phenotyping of post-infectious SARS-CoV-2 patients감염 후 SARS-CoV-2 환자의 인지 표현형Article Published on 2022-08-012022-09-11 Journal: Neurological Sciences [Category] COVID19(2023년), SARS, 치료기술, [키워드] Administered Assessing orientation assessment battery both groups clinically cognitive Cognitive impairment Cognitive impairment: executive functioning confounder COVID-19 Cutoff dysfunction examination executive executive functioning feature fluency Frontal in both groups individual less Measures medical records Mini-Mental State Examination Neuroinvasive Neuropsychology Orientation outcome Patient patients predominant premorbid risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient state variable [DOI] 10.1007/s10072-022-06130-8 PMC 바로가기 [Article Type] Article
Genomic surveillance, evolution and global transmission of SARS-CoV-2 during 2019-20222019-2022년 동안 SARS-CoV-2의 게놈 감시, 진화 및 전 세계 전파Article Published on 2022-08-012022-09-11 Journal: PLoS ONE [Category] SARS, 변종, 유전자 메커니즘, [키워드] analyzed Beta conducted correlation COVID-19 pandemic Delta died E484K Evolution Evolutionary rate fatality followed by Frequency Gamma genomic genomic data Genomic surveillance growth growth rate Health help information L452R likelihood Multiple Multiple sequence alignment Mutation N439K N501Y omicron outcome pandemic Point mutation point mutations predominant prevalent reduce SARS-COV-2 infection sequence Sequence alignment Spike protein Substitution Surveillance transmission of SARS-CoV-2 Vaccine variant variants VoC [DOI] 10.1371/journal.pone.0271074 PMC 바로가기 [Article Type] Article