Longitudinal changes in COVID-19 clinical measures and correlation with the extent of CT lung abnormalitiesObservational Study Published on 2021-01-162022-10-04 Journal: International Journal of Medical Sciences [Category] 임상, [키워드] albumin analyzed C-reactive protein change changes in characteristic corona virus disease 2019 correlated correlation COVID-19 CT declined decrease discharge Duration enrolled evaluated hemoglobin initial laboratory parameter Laboratory parameters Lactate lactate dehydrogenase longitudinal longitudinal change longitudinal changes lung lung abnormality lung involvement Lymphocyte count measure parameter patients with COVID-19 peaked Prognostic factors quantified reduced remained scoring system severe acute respiratory syndrome coronavirus 2 symptom onset timespan zone [DOI] 10.7150/ijms.51279 PMC 바로가기 [Article Type] Observational Study
First wave of COVID-19 hospital admissions in Denmark: a Nationwide population-based cohort studyResearch Article Published on 2021-01-092022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] acute respiratory syndrome Admission age Analysis C-reactive protein CCI Charlson Comorbidity Index Comorbidity competing coronavirus coronavirus disease COVID-19 COVID-19 diagnosis creatinine CRP cumulative D-dimer death demographic demographics determinant died disease elevated Epidemiology Factor female ferritin Follow-up Health Hospital admission hospitalised patient Hospitalised patients hospitalized patient ICU ICU admission identify incidence increase in independent intensive care intensive care unit Laboratory laboratory abnormality laboratory result lactate dehydrogenase LDH lymphopenia male Male sex males median age moderate Mortality Nationwide neutrophil count population-based cohort Prognostic factor Prognostic factors Result risk SARS-CoV-2 significantly higher supplementary material survival systemic inflammation urea were used with COVID-19 [DOI] 10.1186/s12879-020-05717-w PMC 바로가기 [Article Type] Research Article
Association between high-dose steroid therapy, respiratory function, and time to discharge in patients with COVID-19: Cohort study고용량 스테로이드 요법, 호흡 기능, COVID-19 환자의 퇴원 시간 사이의 연관성: 코호트 연구Observational Study Published on 2021-01-082022-09-11 Journal: Medicina clínica [Category] 바이오마커, 임상, [키워드] adjusted Analysis association Cohort cohorts control patients coronavirus COVID-19 Cox multivariate model Cox multivariate models Cox regression Dexametasona Dexamethasone discharge doses Evolution glucocorticoid Glucocorticoides Glucocorticoids hazard ratio High-dose hospital increment log-rank Methylprednisolone Metilprednisolona multivariate no significant difference observational study oxygen Patient patients hospitalized patients treated Primary outcomes Prognostic factors Respiratory function SAFI SARS-CoV-2 significant difference significantly Spain sub-cohort therapy Treatment treatments for COVID-19 with COVID-19 [DOI] 10.1016/j.medcli.2020.08.003 PMC 바로가기 [Article Type] Observational Study
Survival Factors and Metabolic Pathogenesis in Elderly Patients (≥65) With COVID-19: A Multi-Center StudyMedicine Published on 2021-01-072022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age Algorithm Analysis applied ARDS assist Characteristics clinical clinical end point clinical stratification clinically collected COVID-19 COVID-19 infection Deceased discharged distress elderly Elderly patient elderly patients elevated Factor Factors fatty Follow-up hospital hospital discharge increased risk infected with COVID-19 interferon laboratory data laboratory-confirmed mechanism metabolic metabolic pathogenesis metabolic pathway metabolism molecular Mortality Multivariate analysis Neutrophil-to-lymphocyte ratio pathogenesis of SARS-CoV-2 pathogenic pathway flux Pathways Patient patients performed potential risk predict probability of survival Prognostic factors pyruvate receiving reported Risk factors Stratification survival survival factors survived survivor syndrome Treatment Vaccine development with COVID-19 Wuhan [DOI] 10.3389/fmed.2020.595503 PMC 바로가기 [Article Type] Medicine
Risk factors of mortality and contribution of treatment in patients infected with COVID-19: a retrospective propensity score matched studyArticle Published on 2021-01-012023-07-13 Journal: Current medical research and opinion [Category] SARS, [키워드] COVID-19 critical medicine immunomodulatory Mortality Prognostic factors [DOI] 10.1080/03007995.2020.1853508 PMC 바로가기
Prognostic Factors for 30-Day Mortality in Critically Ill Patients With Coronavirus Disease 2019: An Observational Cohort StudyObservational Study Published on 2021-01-012022-10-05 Journal: Critical Care Medicine [Category] 임상, [키워드] 24 hour 30-Day mortality age association Blood body mass index Characteristics cohort study Concentration continuous variable coronavirus disease Cox proportional hazard Critical care Critically ill cubic splines death Deprivation died eligible eligible patient England Factor hemoglobin highest hospital identify Ill Immunocompromise Interaction Ireland Lactate less likelihood lowest main outcome measure male measurement mechanical ventilation median age Patient Platelet predict Prognostic factor Prognostic factors receiving respiratory rate Sedation serum Sex Significant Support Systolic blood pressure temperature urea variable variables [DOI] 10.1097/CCM.0000000000004740 PMC 바로가기 [Article Type] Observational Study
Prior surveillance and antiviral treatment improve the prognosis of HCC developed in HBV patients in the WestArticle Published on 2021-01-012023-06-12 Journal: Clinics and research in hepatology and gastroenter [Category] B형 간염, [키워드] hepatitis B infection Hepatocellular carcinoma overall survival Prognostic factors [DOI] 10.1016/j.clinre.2020.03.030
Compassionate use of tocilizumab in severe SARS-CoV2 pneumonia중증 SARS-CoV2 폐렴에서 토실리주맙의 동정적 사용Article Published on 2021-01-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 신약개발, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome Administered administration age analyzed ARDS benefit C-reactive protein compassionate-use COVID-19 CRS cytokine Cytokine release syndrome D-dimer death dose drug Evolution Factor FiO2 high oxygen support High-sensitivity C-reactive protein Hospitalized hsCRP IL-6 intensive care interleukin-6 interleukin-6 receptor intravenous Intubated intubation Lymphocytes male Older age oxygen oxygen support Patient patients Pneumonia primary endpoint Prognostic factors receiving receptor antagonist required respiratory distress SARS-CoV-2 SARS-CoV-2 pneumonia SARS-CoV2 saturation severe disease severe SARS severe SARS-CoV-2 significantly syndrome TCZ Tocilizumab Treatment [DOI] 10.1016/j.ijid.2020.10.045 PMC 바로가기 [Article Type] Article
Previous and First Detected Cardiovascular Diseases in Patients with New Coronavirus Pneumonia: Possible Mechanisms and Place in a Unified Prognostic Model신종 코로나바이러스 폐렴 환자에서 이전 및 최초로 발견된 심혈관 질환: 통합 예후 모델에서 가능한 기전 및 위치Article Published on 2021-01-012022-09-12 Journal: International archives of allergy and immunology [Category] 진단, [키워드] addition age AHA Anti-heart antibodies antibody average C-reactive protein cardiac cardiovascular cardiovascular disease cause coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia correlation correlation coefficient COVID-19 D-dimer death diabetes disease disorders evaluate Frequency heart failure Heart injury hospital immune mechanism incidence include indicate Inflammatory inflammatory activity Injury lethality leukocyte male Manifestations mechanisms Model myocardial injury myocarditis New Oxygen therapy pathology Patient patients with COVID-19 Pneumonia predictive power Prognosis Prognostic factors prognostic model prothrombotic Respiratory failure sensitivity Significant specificity Symptom Symptoms Volume was increased were used with COVID-19 [DOI] 10.1159/000515253 PMC 바로가기 [Article Type] Article
Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19COVID-19와 관련된 숙주 유전자의 우선 순위를 지정하기 위한 동적 데이터 기반 메타 분석Meta-Analysis Published on 2020-12-182022-09-10 Journal: Scientific Reports [Category] MERS, 바이오마커, 유전자 메커니즘, 임상, 치료제, [키워드] Algorithm Betacoronavirus CD3E CD4 chromosome chromosome 3 conducted content COVID-19 COVID-19 pathogenesis CXCL10 cyclosporine data-driven datasets described disease-associated dynamic evaluate Evidence experiment Factor Factors FYCO1 GWAS Host host gene host genes human betacoronavirus IL1A Immunogenetics immunology implicated Infection Infectious diseases Interpretation list list of gene locus MERS MERS-CoV Meta-analysis Other PPIA Prognostic factor Prognostic factors resource robust SARS-CoV SARS-CoV-2 seasonal coronaviruses systematic review therapeutic target Therapies viral infection Weighting [DOI] 10.1038/s41598-020-79033-3 PMC 바로가기 [Article Type] Meta-Analysis