Comparative Assessment of Filtration- and Precipitation-Based Methods for the Concentration of SARS-CoV-2 and Other Viruses from WastewaterArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 치료기술, 치료제, [키워드] Adenovirus affected Ammonium Analysis approaches assessment centrifugation Characteristics Community Comparative Concentration COVID-19 COVID-19 pandemic develop Enteric viruses Environmental virology Epidemiology evaluated experiments fecal FIVE Genome glycol human respiratory viruses in viral Influenza information Laboratory Mild murine National Other pathogen detection pathogenic virus physico-chemical property public health public health surveillance quantification rapid expansion SARS-CoV-2 SARS-COV-2 infection selected sewage concentration. subsequent Surveillance tested virus virus detection virus particle virus titer viruses Volume wastewater [DOI] 10.1128/spectrum.01102-22 PMC 바로가기
High-Throughput COVID-19 Testing of Naso-Oropharyngeal Swabs Using a Sensitive Extraction-Free Sample Preparation MethodArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 치료기술, [키워드] approach calibrated Cobas costly COVID-19 detection system diagnosis of SARS-CoV-2 diagnostic Direct direct method downstream extraction-free extraction-free method gold standard High-throughput Infection International lack less log medium naso-oropharyngeal swab nasopharyngeal swab specimen nucleic acid extraction offer ORF1ab outcome PCR PCR assay per day PlexPCR pool positive sample preparation proteinase protocol purification quantification RdRP reagent reagents reduction in required Respiratory Coronavirus reverse transcription-PCR RNA Roche Sample SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA sensitive sensitivity tested Testing time-consuming Transport Treatment Viral load Viral RNA WHO [DOI] 10.1128/spectrum.01358-22 PMC 바로가기
Circulating Ubiquitous RNA, A Highly Predictive and Prognostic Biomarker in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients순환 유비쿼터스 RNA, 입원한 코로나바이러스 질환 2019(COVID-19) 환자의 고도로 예측하고 예후가 좋은 바이오마커Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admission Biomarker Biomarkers Blood cell lysis Chain Reaction circulating Clinical management clinical monitoring clinical outcomes Clinical severity coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patients Critical ddPCR death develop disease severity Diseases evaluate Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Infectious diseases Invasive mechanical ventilation lung cell management marker multi-organ failure organ injury overall survival Patient plasma polymerase chain polymerase chain reaction predict Predictive predictive and prognostic biomarkers prognostic Prognostic biomarkers quantification respiratory respiratory distress Respiratory distress syndrome RNA RNase P RNAseP SARS-CoV-2 SARS-CoV-2 and RNAseP RNAemia severe acute respiratory syndrome Coronavirus severe and critical patients severity significantly survival syndrome tissue injury tissue/cell lysis biomarker. Viral [DOI] 10.1093/cid/ciab997 PMC 바로가기 [Article Type] Article
Saliva as Blood Alternative in Therapeutic Monitoring of Teriflunomide-Development and Validation of the Novel Analytical MethodArticle Published on 2022-08-232022-11-16 Journal: International Journal of Molecular Sciences [Category] SARS, 치료기술, [키워드] analyzed biologically active metabolite Blood can be used characterized collected Concentration correlation criteria dosage drug Effectiveness evaluated Good LC-MS/MS leflunomide life-threatening linear monitoring Non-invasive novel pharmacokinetic plasma quantification reduce regimen robust Saliva salivary SARS-CoV-2 pandemic Side effect stimulated Swab Teriflunomide therapeutic therapeutic drug Therapeutic Drug Monitoring validation Variability was obtained [DOI] 10.3390/ijms23179544 PMC 바로가기
Use of wastewater surveillance for early detection of Alpha and Epsilon SARS-CoV-2 variants of concern and estimation of overall COVID-19 infection burden우려의 알파 및 엡실론 SARS-CoV-2 변종 조기 감지 및 전체 COVID-19 감염 부담 추정을 위한 폐수 감시 사용Article Published on 2022-08-202022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] Alpha Amplicon analyzed B.1.1.7 B.1.429 Clinical data clinical testing Concentration COVID-19 COVID-19 incidence COVID-19 infection diagnostic diagnostic testing effective eight Epsilon expected fecal identify individual Infection infectious agents Lineage log Mutation quantification ranged reported RNA concentrations SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 variant Sequencing Seroprevalence several limitation several limitations significantly higher Surveillance surveillance data The United States trend United States variant variants variants of concern virus wastewater WGS whole genome Whole genome sequencing [DOI] 10.1016/j.scitotenv.2022.155410 PMC 바로가기 [Article Type] Article
SARS-CoV-2 antibody progression and neutralizing potential in mild symptomatic COVID-19 patients – a comparative long term post-infection studyArticle Published on 2022-08-172022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] acute infections addition Antibody titer block CLIA clinician Cohort comparability comparable convalescent COVID-19 disease COVID-19 patient Cutoff diagnostics ELISA FIVE help immune immune response increasingly individual immune response Infection information Laboratory long-COVID long-term assay comparison Mild mild progression COVID-19 mild SARS-CoV-2 infection Molecular diagnosis neutralization Neutralizing neutralizing potential Occurrence offered pandemic participant Participants Patient Post-infection progression quantification quantification immune response. Rapid SARS-CoV-2 SARS-CoV-2 antibody serological serological test specific antigen Support Symptom symptomatic vaccination Vaccine WHO [DOI] 10.3389/fimmu.2022.915338 PMC 바로가기
A fast and sensitive absolute quantification assay for the detection of SARS-CoV-2 peptides using parallel reaction monitoring mass spectrometry병렬 반응 모니터링 질량 분석을 사용한 SARS-CoV-2 펩타이드 검출을 위한 빠르고 민감한 절대 정량 분석Article Published on 2022-08-152022-09-11 Journal: Journal of proteomics [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] Absolute quantification Clinical diagnosis clinics COVID-19 Ct values Early detection enrichment heat heat-inactivated high resolution high viral load investigated mass mass spectrometry Nasopharyngeal swab nasopharyngeal swab sample Orbitrap pandemic Patient peptide peptides positive positive patient positive patients PRM Protein quantification required RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 nucleocapsid SARS-CoV-2 peptide sensitivity speed Surveillance swab samples the disease Viral load Viral protein Viral proteins [DOI] 10.1016/j.jprot.2022.104664 PMC 바로가기 [Article Type] Article
Wastewater and marine bioindicators surveillance to anticipate COVID-19 prevalence and to explore SARS-CoV-2 diversity by next generation sequencing: One-year studyCOVID-19 유행을 예측하고 차세대 염기서열 분석을 통해 SARS-CoV-2 다양성을 탐색하기 위한 폐수 및 해양 생물지표 감시: 1년 연구Article Published on 2022-08-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 바이오마커, 변종, 치료기술, [키워드] a minor Analysis Biomarker Combination COVID-19 detect discharge eliminated Epidemiology Evolution Final Forecasting health system mathematical minor outbreak pandemic plant predict Predictive model Prevalence provided quantification RNA sampling SARS-CoV-2 SARS-CoV-2 sequencing SARS-CoV-2 surveillance Seawater Spain stochastic stochastic SIR model Surveillance the marine treated Treatment Viral Viral load virus virus variants was used wastewater Wastewater-based epidemiology water [DOI] 10.1016/j.scitotenv.2022.155140 PMC 바로가기 [Article Type] Article
Direct comparison of RT-ddPCR and targeted amplicon sequencing for SARS-CoV-2 mutation monitoring in wastewater폐수에서 SARS-CoV-2 돌연변이 모니터링을 위한 RT-ddPCR과 표적 앰플리콘 시퀀싱의 직접 비교Article Published on 2022-08-102022-09-11 Journal: The Science of the total environment [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Amplicon sequencing Analysis analyzed applied approach ARTIC association breakthrough infections characteristic contagious Course Coverage COVID-19 pandemic determined by Direct Epidemiology event FIVE gold gold standard highlighting Mutation mutations over positive quantification quantitative measurement referred to reported RT-ddPCR SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 variant SARS-CoV-2 variants sensitivity Sequencing variants variants of concern variants of concern (VOC) variants of SARS-CoV-2 VOCs wastewater wastewater-based epidemiology (WBE) [DOI] 10.1016/j.scitotenv.2022.155059 PMC 바로가기 [Article Type] Article
COVID-19 pandemic dynamics in South Africa and epidemiological characteristics of three variants of concern (Beta, Delta, and Omicron)남아프리카 공화국의 COVID-19 대유행 역학 및 세 가지 우려 변종(베타, 델타 및 오미크론)의 역학적 특성Article Published on 2022-08-092022-09-11 Journal: eLife [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition African Beta Characteristics coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 pandemic Delta disease driver epidemiological epidemiological data Epidemiology estimate global health help immune immune evasion independent Infection infection rate Model New coronavirus nine None Nonpharmaceutical interventions omicron pandemic parameter public health quantification Reinfection reinfection rate retrospective risk SARS-CoV-2 SARS-CoV-2 transmission severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 South South Africa trajectory Transmissibility vaccination variant variant of concern variants of concern VoC VOCs [DOI] 10.7554/eLife.78933 PMC 바로가기 [Article Type] Article