Avian Orthoavulavirus Type-1 as Vaccine Vector against Respiratory Viral Pathogens in Animal and HumanReview Published on 2022-02-082022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Adaptive immune response animal avian orthoavulaviruses type-1 expression feature Genes Genome Host hosts Human humans include lack limitation mammalian mammalian cell mammals membrane mitigations strategies offer pre-existing immunity protocol Recombination respiratory Respiratory pathogens robust safety profile transitioned unique Vaccine vaccine antigen Vaccines vector vectors viral pathogen virus [DOI] 10.3390/vaccines10020259 PMC 바로가기 [Article Type] Review
Ongoing Recombination in SARS-CoV-2 Revealed through Genealogical Reconstruction족보 재구성을 통해 밝혀진 SARS-CoV-2의 진행 중인 재조합Discoveries Published on 2022-02-022022-09-10 Journal: Molecular Biology and Evolution [Category] COVID19(2023년), MERS, SARS, 변종, 치료기술, [키워드] Affect collected Effect England Evidence evidence of genealogy Genetic genetic diversity genetic recombination Inference parsimony phylogenetic analyses Phylogenetic analysis Probability Recombination recombination event reconstruction recurrent mutation resolved Revealed SARS-CoV-2 SARS-CoV-2 sequences sequencing data significantly South Africa statistical framework Treatment Vaccines Viral viral pathogen [DOI] 10.1093/molbev/msac028 PMC 바로가기 [Article Type] Discoveries
Towards an efficient collection and transport of COVID-19 diagnostic specimens using genetic-based algorithmsResearch article Published on 2022-02-012022-10-05 Journal: Applied Soft Computing [Category] 진단, [키워드] Algorithm Ambulance routing approach approaches assigned collected conditions COVID-19 COVID-19 pandemic COVID-19 specimen transport data sets diagnostic effective Effectiveness Efficiency experiments Health hospital hybrid Hybrid genetic algorithm initial instance instances Local Memetic algorithm operator Patient performed problem protocol reached receiving Recombination specimen Spread statistical analysis structures supported Symptom team Team orienteering problem the patient transferred Transport Tunis [DOI] 10.1016/j.asoc.2021.108264 [Article Type] Research article
Evolution of the SARS-CoV-2 genome and emergence of variants of concernSARS-CoV-2 게놈의 진화와 우려되는 변이체의 출현Review Published on 2022-02-012022-09-11 Journal: Archives of Virology [Category] COVID19(2023년), SARS, 변종, [키워드] accumulation Administered Alpha Antibody neutralization B.1.1.7 B.1.351 B.1.617.2 Beta change changes in chronic infections clade consequence coronavirus described Evolution immune response immune responses imperative Infection initial Lineage mortality rate mortality rates notable observation P.1 promote raised random Recombination recurrent infection Replication RNA SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 lineage segregation sequence sequence variation spike gene strain Strains Surveillance the SARS-CoV-2 genome the vaccine Transmission variants variants of concern Variation variations while whole-genome sequencing [DOI] 10.1007/s00705-021-05295-5 PMC 바로가기 [Article Type] Review
Detection of homologous recombination events in SARS-CoV-2Article Published on 2022-01-172023-06-15 Journal: Biotechnology letters [Category] MERS, SARS, [키워드] pangolin Phylogeny Rattus RDP Recombination SARS-CoV-2 [DOI] 10.1007/s10529-021-03218-7 PMC 바로가기
Genomic Surveillance Enables the Identification of Co-infections With Multiple SARS-CoV-2 Lineages in Equatorial Guinea게놈 감시를 통해 적도 기니에서 여러 SARS-CoV-2 계통과의 동시 감염 식별 가능Case Reports Published on 2022-01-042022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] activities activity addition Asymptomatic Beta caused Central-Africa clinically Co-infection COVID-19 COVID-19 disease Delta Delta VOC epidemiological situation Equatorial Guinea Evolution Genetic genetic recombination Genomic surveillance global public health identification immune evasion island knowledge Multiple National Public public health Rapid Recombination response resulting SARS-CoV-2 SARS-CoV-2 genomic surveillance SARS-CoV-2 lineage SARS-CoV-2 variant SARS-CoV-2 variants Spread Surveillance the SARS-CoV-2 Transmission variant of concern VoC [DOI] 10.3389/fpubh.2021.818401 PMC 바로가기 [Article Type] Case Reports
USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AIDArticle Published on 2022-01-042022-10-29 Journal: Signal Transduction and Targeted Therapy [Category] COVID-19, [키워드] acute respiratory syndrome adjuvants Affect antibody B cell B cell response BCR coronavirus Cytidine deaminase deficiency demonstrated deubiquitinase domain expression Extracellular function Genes HIV-1 Human immunodeficiency virus immunization immunology initiate mechanisms Molecular biology neutralizing antibody NLS nuclear nucleus Phosphorylation promoted Protein protein levels Recombination reducing regulate SARS-CoV-2 significantly TLR USP10 Vaccine Vaccines [DOI] 10.1038/s41392-021-00858-z PMC 바로가기 [Article Type] Article
The Remarkable Evolutionary Plasticity of Coronaviruses by Mutation and Recombination: Insights for the COVID-19 Pandemic and the Future Evolutionary Paths of SARS-CoV-2돌연변이 및 재조합에 의한 코로나 바이러스의 현저한 진화 가소성 : Covid-19 Pandemic과 SARS-Cov-2의 미래 진화 경로에 대한 통찰력Review Published on 2022-01-022022-09-10 Journal: Viruses [Category] SARS, 변종, 신약개발, 치료제, [키워드] addition Affect B.1.1.529 birds coronavirus CoV CoV protein CoV proteins COVID-19 COVID-19 pandemic CoVs deletions Epidemics Evolution FIVE focus Future Health highlight homologous Human insertions insight mammal molecular molecular evolution mutations non-homologous omicron pandemic path point mutations positive-sense single-stranded RNA positive-sense single-stranded RNA viruses Recombination recombination event SARS-CoV-2 SARS-CoV-2 pandemic spike strain Transmissibility Vaccine Vaccines viruses zoonotic origin [DOI] 10.3390/v14010078 PMC 바로가기 [Article Type] Review
Detection and Molecular Characterization of Canine Alphacoronavirus in Free-Roaming Dogs, BangladeshBrief Report Published on 2021-12-302022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] alphacoronavirus Bangladesh canine cause characterization China circulating collected conducted Corona coronavirus CoV cross-sectional detect detection disorders Epidemiology Filo Genetic Genotype Human humans Interaction pathogen positive Recombination RT-PCR sequenced Sequencing strain swab sample tested Transmission virus widespread zoonotic zoonotic transmission [DOI] 10.3390/v14010067 PMC 바로가기 [Article Type] Brief Report
Analysis of TCR Repertoire by High-Throughput Sequencing Indicates the Feature of T Cell Immune Response after SARS-CoV-2 InfectionArticle Published on 2021-12-272022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] analyzed caused CD4 CD8 CDR3 characteristic clearance clone Clustering Combination contributing to convalescent convalescent COVID-19 patients coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients dominant donors feature Frequency group healthy control immune memory immune response Infection Infectious disease Invasion J gene motif provide Recombination repertoire response SARS-CoV-2 SARS-CoV-2 antigen sequence Sequencing Specificities stages T cell T cell receptor T cell response TCR the healthy the SARS-CoV-2 virus virus recognition [DOI] 10.3390/cells11010068 PMC 바로가기 [Article Type] Article