sequencing data – Page 7 – Communicable Diseases Research

Recommendations for accurate genotyping of SARS-CoV-2 using amplicon-based sequencing of clinical samples

앰플리콘 기반 임상 샘플 시퀀싱을 사용한 SARS-CoV-2의 정확한 유전자형에 대한 권장 사항

Article

Published on 2021-07-012022-09-11
Journal: Clinical microbiology and infection : the official [Category] SARS, 변종, 치료기술,

Genetic epidemiology of SARS-CoV-2 transmission in renal dialysis units – A high risk community-hospital interface

신장 투석실에서 SARS-CoV-2 전파의 유전 역학 - 고위험 지역사회-병원 인터페이스

Article

Published on 2021-07-012022-09-11
Journal: The Journal of Infection [Category] SARS, 유전자 메커니즘,

High-precision and cost-efficient sequencing for real-time COVID-19 surveillance

실시간 CovID-19 감시를위한 고정밀 및 비용 효율적인 시퀀싱

Article

Published on 2021-07-012022-09-01
Journal: Scientific Reports [Category] SARS, 변종, 유전자 메커니즘, 진단,

[키워드] Amino acid amplified clade coronavirus COVID-19 COVID-19 patients COVID-19 test deaths disease disease outbreaks full-length genome coverage genomic genomic RNA Genomic surveillance High-throughput sequencing individual Los Angele Los Angeles Molecular medicine Mutation nine Nsp12 ORF8 Outbreaks platform positive Precision produced public health reduced Sanger sequencing SARS-CoV-2 sequence sequenced Sequencing sequencing data significantly Surveillance swab specimen the SARS-CoV-2 Threats Transmission USA Viral viral infection Viral RNA whole genome whole genome sequence Whole genome sequencing
[DOI] 10.1038/s41598-021-93145-4 PMC 바로가기 [Article Type] Article

Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data

Tools and Resources

Published on 2021-06-292022-10-31
Journal: eLife [Category] COVID-19, MERS, SARS,

[키워드] acquisition Admission Algorithm analysed Clusters COG-UK COG-UK consortium collected COVID-19 COVID-19 infection dataset defined epidemiological epidemiological data events first positive healthcare Healthcare associated hospital Human identify Incubation period Infection Infection prevention information Innovation Interpretation methodology Mutation nosocomial outbreak Phylogenetic potential transmission Probability provide Rapid resulting retrospective SARS-CoV-2 SARS-COV-2 infection sequence sequencing data statistical supported Transmission Wellcome Sanger Institute Whole genome sequencing
[DOI] 10.7554/eLife.65828 PMC 바로가기 [Article Type] Tools and Resources

Identification of a High-Frequency Intrahost SARS-CoV-2 Spike Variant with Enhanced Cytopathic and Fusogenic Effects

세포변성 및 융합생성 효과가 강화된 고주파수 인트라호스트 SARS-CoV-2 스파이크 변이체 식별

Research Article

Published on 2021-06-292022-09-10
Journal: mBio [Category] MERS, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid amino acids analyzed coronavirus COVID-19 cytopathic effects data sets disease Diversity Effect enhanced Evolution exhibit exonuclease Factors Frequency gene encoding genetic diversity Genetic variant genetic variants High-throughput sequencing Host hosts identification infected cell infected individual infected individuals involved M protein Missense mutation molecular molecular evolution MOST Mutation Neutral produced Proofreading Protein Quasispecies Replication respiratory resulting RNA-dependent RNA polymerase S protein SARS-CoV-2 SARS-CoV-2 variants sequence sequencing data severe acute respiratory syndrome Coronavirus spike Spike protein Syncytia syncytium formation the S protein transmitted Variation variations Viral viral spike virus
[DOI] 10.1128/mBio.00788-21 PMC 바로가기 [Article Type] Research Article

Large-scale sequencing of SARS-CoV-2 genomes from one region allows detailed epidemiology and enables local outbreak management

한 지역에서 SARS-CoV-2 게놈의 대규모 시퀀싱을 통해 자세한 역학이 가능하고 지역 발병 관리가 가능합니다.

Research Articles

Published on 2021-06-292022-09-10
Journal: Microbial Genomics [Category] MERS, SARS, 치료기술,

[키워드] activities activity analyses ARTIC assist Care clinical sample COG-UK collected Community community organizations COVID-19 COVID-19 pandemic D614G effort Epidemiology Evidence evidence of Evolution expansion Genetic variation Genome genome sequence Genome sequences Genome sequencing Genomic epidemiology Genomics Health help hidden hospital hospitals identify infection control initial Lineage lineages Local Longitudinal data longitudinal samples low-density management measure Metadata Mutation National NGS no evidence of nosocomial organization outbreak pandemic patients Phylogenetic positive positive sample progressed provided public health Reinfection reported SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes Sequencing sequencing data SNPs Spike protein Spread the SARS-CoV-2 genome Transmissibility Transmission virus whole genome Whole genome sequencing
[DOI] 10.1099/mgen.0.000589 PMC 바로가기 [Article Type] Research Articles

Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV‐CATCHER): A customizable purification assay designed for small‐RNA biomarker identification and evaluation of circulating small‐EVs

Technical Report

Published on 2021-06-032022-10-29
Journal: Journal of Extracellular Vesicles [Category] COVID-19, MERS,

Genome‐wide screening of SARS‐CoV‐2 infection‐related genes based on the blood leukocytes sequencing data set of patients with COVID‐19

Research Article

Published on 2021-05-282022-11-01
Journal: Journal of medical virology [Category] COVID-19, SARS,

[키워드] ACE2 acute respiratory syndrome adverse effect Analysis analyzed AUC AUC value bioinformatics blood leukocyte calculated caused contribute coronavirus Coronavirus disease 2019 COVID‐19 COVID‐19 patient COVID‐19 CTSB CTSL DEGs Diagnosis diagnostic differentially expressed gene disease enrichment analysis Epidemic EPSTI1 expressed expression function Gene ontology GEO database Health IFI27 IFIT3 leukocyte Logistic regression analysis mechanism OASL Patient positively correlated Protein–protein interaction risk ROC Curve SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 screened sequencing data therapeutic therapeutic target TMPRSS2 Treatment USP18 virus XAF1
[DOI] 10.1002/jmv.27093 PMC 바로가기 [Article Type] Research Article

Viral fibrotic scoring and drug screen based on MAPK activity uncovers EGFR as a key regulator of COVID-19 fibrosis

MAPK 활성을 기반으로 한 바이러스성 섬유증 스코어링 및 약물 스크리닝은 COVID-19 섬유증의 주요 조절자로서 EGFR을 밝혀냅니다

Article

Published on 2021-05-272022-09-10
Journal: Scientific Reports [Category] 신약개발, 치료제,

[키워드] ACE2 activity Analysis Antiviral antiviral activity approach Cell cell line Cell signalling Cluster cluster of gene complication of COVID-19 correlation COVID-19 COVID-19 progression COVID-19 research COVID-19 treatment Data mining Data processing downregulate drug Drug discovery dual EGF EGFR entry receptor epidermal epidermal growth factor ErbB ERK fibrosis growth factor Host Idiopathic pulmonary fibrosis imaging in vitro infected cells inhibitor inhibitors involved lung cells machine learning MAPK molecular basis Patient phenotype predicted provide pulmonary fibrosis quantified responsible RNA-sequencing SARS-CoV-2 SARS-CoV-2-infected cell SARS-CoV-2-infected cells sequencing data Signaling the cells transcriptomic transcriptomic data Treatment understanding utility Virtual drug screening
[DOI] 10.1038/s41598-021-90701-w PMC 바로가기 [Article Type] Article

SARS-CoV-2 mutations among minks show reduced lethality and infectivity to humans

밍크 중 SARS-CoV-2 돌연변이는 인간에 대한 치사율 및 감염력 감소를 보여줍니다

Research Article

Published on 2021-05-262022-09-10
Journal: PLoS ONE [Category] MERS, SARS, 변종,

[키워드] accounted analysed Characteristics country Human humans infective less mutate mutated Netherlands reduced SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 mutation sequencing data vaccination variant variants virus
[DOI] 10.1371/journal.pone.0247626 PMC 바로가기 [Article Type] Research Article