sera – Page 7 – Communicable Diseases Research

Preclinical study of formulated recombinant nucleocapsid protein, the receptor binding domain of the spike protein, and truncated spike (S1) protein as vaccine candidates against COVID-19 in animal models

동물 모델에서 COVID-19에 대한 백신 후보로서 제형화된 재조합 뉴클레오캡시드 단백질, 스파이크 단백질의 수용체 결합 도메인 및 절단 스파이크(S1) 단백질의 전임상 연구

Article

Published on 2022-09-012022-09-11
Journal: Molecular immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료법,

SARS-CoV-2 surveillance in Norway rats (Rattus norvegicus) from Antwerp sewer system, Belgium

Article

Published on 2022-09-012022-11-15
Journal: Transboundary and emerging diseases [Category] SARS, 변종, 진단,

Screening of wild deer populations for exposure to SARS-CoV-2 in the United Kingdom, 2020-2021

Article

Published on 2022-09-012022-11-15
Journal: Transboundary and emerging diseases [Category] COVID19(2023년), SARS, 변종, 진단,

Humoral and adaptive immune responses to the SARS-CoV-2 vaccine

Article

Published on 2022-09-012022-11-15
Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단,

Durability of Immune Response After COVID-19 Booster Vaccination and Association With COVID-19 Omicron Infection

Article

Published on 2022-09-012022-11-15
Journal: JAMA Network Open [Category] SARS, 변종, 진단,

[키워드] 95% CI age antibody antibody kinetics Antibody titer antibody waning association avidity BNT162b2 BNT162b2 vaccine booster dose COVID-19 delta variant demonstrated dose effective Effectiveness faster Follow-up geometric mean titer greater Health care worker Humoral response IgG IgG level immune response incidence Infection longitudinal cohort study microneutralization mononuclear cell mononuclear cells neutralization neutralizing antibody Older omicron outcome participant Peripheral blood Primary outcome response SARS-CoV-2 second dose secondary outcome sera Strains susceptibility T cell T cell activation tested Transmission Vaccine vaccine dose vaccine doses variant variant of SARS-CoV-2 variants of concern were assessed were used wild type women
[DOI] 10.1001/jamanetworkopen.2022.31778 PMC 바로가기

Effectiveness of the third dose of BNT162b2 vaccine on neutralizing Omicron variant in the Japanese population

일본 인구에서 오미크론 변이체 중화에 대한 BNT162b2 백신 3차 접종의 효과

Article

Published on 2022-09-012022-09-11
Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] acquired immunity Anti-receptor binding domain antibody anti-SARS-CoV-2 antibody binding domain BNT162b2 BNT162b2 vaccine booster booster vaccination collected contribute COVID-19 case COVID-19 cases declines Delta dose Efficacy elevated evaluated event fatigue Fever healthcare worker Healthcare workers humoral Humoral immunity Immunity individual Japanese Local local swelling median myalgia neutralization Neutralizing Neutralizing activity neutralizing antibody of BNT162b2 omicron Omicron variant Pfizer promotion provide Pseudotyped viruses Questionnaires reduced SARS-CoV-2 second dose sera serum sample serum samples Side effect Side effects significantly swelling Toyama U/mL university vaccination Vaccine variant variants was measured Waves wild-type
[DOI] 10.1016/j.jiac.2022.05.009 PMC 바로가기 [Article Type] Article

Neutralization Titers in Vaccinated Patients with SARS-CoV-2 Delta Breakthrough Infections

Article

Published on 2022-08-302022-11-15
Journal: mBio [Category] SARS, 변종, 진단,

A Bacteriophage-Based, Highly Efficacious, Needle- and Adjuvant-Free, Mucosal COVID-19 Vaccine

Article

Published on 2022-08-302022-11-15
Journal: mBio [Category] COVID19(2023년), SARS, 변종, 진단,

[키워드] addition adenovirus-based Administered administration ambient Antibody titer bacteriophage CRISPR engineering bacteriophage T4 mucosal platform BALB/c broad immunity to SARS-CoV-2 variants bronchoalveolar lavage specimen bronchoalveolar lavage specimens caused CD4 CD8 Cell-mediated immune responses cellular immune responses Complete COVID COVID-19 CRISPR cytokine death delta variant dose drug effective elicited enzyme Epidemic exhibited exterior food generate globe gut microbiota hACE2 humoral Immunity induce Infection injected interior intramuscularly intranasal intranasally lung lesion mice mouse-adapted SARS-CoV-2 mRNA mucosal nasal needle needle-free intranasal vaccine not affect nucleocapsid protein omicron other respiratory infection pandemic Pathogens phage T4 platform predicted Prevent provide provided response responses robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants secretory IgA sera spike sterilizing immunity. T cell temperature the United State the vaccine Transgenic mouse Transmission trimer Vaccine variants Viral transmission Virus neutralization virus-neutralizing antibody World Health Organization
[DOI] 10.1128/mbio.01822-22 PMC 바로가기

IgG Against Human Betacoronavirus Spike Proteins Correlates With SARS-CoV-2 Anti-Spike IgG Responses and COVID-19 Disease Severity

Article

Published on 2022-08-262022-11-15
Journal: The Journal of Infectious Diseases [Category] SARS, 진단,

[키워드] acute respiratory syndrome Against anti-S anti-S antibody anti-S2 anti-SARS-CoV-2 antibody Anti-spike antibody Antibody Response bidirectional cohorts common cold common cold human coronaviruses (HCoVs) coronavirus correlated COVID-19 cross-react cross-reactive antibody cross-reactive antibody response decrease disease disease severity domain Effect elicited HKU1 homologous Human human coronavirus IgG IgG antibody immune immune imprinting. Immunoglobulin morbidity and mortality Multiplex assay OC43 Organ failure Protective RaTG13 recognizing response S proteins S1-reactive antibodies SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection sera serum sample severe coronavirus disease Severity of disease significantly increased SOFA spike strain subject with COVID-19
[DOI] 10.1093/infdis/jiac022 PMC 바로가기

Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Boosts Neutralizing Activity Against Seasonal Human Coronaviruses

중증 급성 호흡기 증후군 코로나바이러스 2 백신 접종은 계절성 인간 코로나바이러스에 대한 중화 활성을 향상시킵니다

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료법,

[키워드] 229E activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Against analyzed average BNT162b2 causative agent ChAdOx1 ChAdOx1 nCoV-19 circulating colds common cold Concentration coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccinations cross-neutralization cross-protection determined by Efficiency Endemic Gene Expression HCoV HCoV-229E HCoV-NL63 HCoV-OC43 HCoVs Heterologous Huh-7 cells Human human coronavirus incubated individual inhibitory activity MERS MERS-CoV Middle East Middle East respiratory syndrome MOST neutralization neutralize Neutralizing activity NL63 nucleocapsid expression OC43 Preexisting immunity pseudoparticle pseudovirion pseudovirions reporter reporter gene respiratory SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 vaccination seasonal seasonal coronavirus seasonal coronaviruses sera severe acute respiratory syndrome Coronavirus significantly increased Spike proteins these viruses vaccination Viral RNA virus
[DOI] 10.1093/cid/ciac057 PMC 바로가기 [Article Type] Article