Reduced Serological Response to COVID-19 Vaccines in Patients with IBD is Further Diminished by TNF Inhibitor Therapy; Early Results of the VARIATION study [VAriability in Response in IBD Against SARS-COV-2 ImmunisatiON]Article Published on 2022-09-082022-11-15 Journal: Journal of Crohn's & colitis [Category] SARS, 진단, [키워드] Affect Against antagonists anti-SP IgG Anti-spike anti-TNF anti-tumour necrosis factor antagonists. Antibody Response booster vaccination bowel Cohort Complete COVID-19 COVID-19 vaccination determine Diagnosis diminished healthy control highlight IBD Immunoglobulin Impaired Inflammatory bowel disease inhibitor investigated medication mRNA vaccine Necrosis Patient Protein Quantitative receiving recruited response response to vaccination Result SARS-CoV-2 vaccination seroconvert seroconverted serological response significantly lower therapy TNF TNF antagonist Treatment vaccination vaccination against COVID-19 Vaccine vaccine response were assessed [DOI] 10.1093/ecco-jcc/jjac029 PMC 바로가기
Plasma and memory antibody responses to Gamma SARS-CoV-2 provide limited cross-protection to other variants감마 SARS-CoV-2에 대한 혈장 및 기억 항체 반응은 다른 변이체에 대해 제한된 교차 보호를 제공합니다Article Published on 2022-09-052022-09-11 Journal: The Journal of Experimental Medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antibody Antibody Response Beta class Cohort coronavirus cross-protection Delta elicited Epitopes evade exposure to Gamma Hospitalized implication individuals infected individual infected individuals Infection infections memory memory B cell memory B cells memory response monoclonal antibodies neutralization neutralize neutralized Neutralizing activity Neutralizing antibodies neutralizing antibody omicron other variant other variants plasma provide pseudotyped pseudovirus pseudoviruses respiratory SARS-CoV-2 SARS-CoV-2 spike protein severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly lower Spike protein vaccination variant variant-specific vaccine variant-specific vaccines variants variants of concern virus viruses Wuhan Wuhan-Hu-1 [DOI] 10.1084/jem.20220367 PMC 바로가기 [Article Type] Article
Neutralising activity and antibody titre in 10 patients with breakthrough infections of the SARS-CoV-2 Omicron variant in Japan일본 SARS-CoV-2 오미크론 변이형 돌발성 감염 환자 10명의 중화 활성 및 항체 역가Article Published on 2022-09-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amino acid Antibody titre Breakthrough infection breakthrough infections caused coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) dose elicited evade examined Immunity induce Japan Mutation Neutralising activity omicron Omicron variant Patient respiratory severe acute respiratory syndrome Coronavirus significantly lower Spike proteins the SARS-CoV-2 titre vaccination variant Wuhan strain [DOI] 10.1016/j.jiac.2022.04.018 PMC 바로가기 [Article Type] Article
Pilot study for immunoglobulin E as a prognostic biomarker in coronavirus disease 2019Article Published on 2022-09-012022-11-15 Journal: Internal medicine journal [Category] SARS, 바이오마커, 진단, [키워드] Admission age Analysis average baseline Biomarker C-reactive protein changes in clinical progression clinically Concentration coronavirus disease COVID-19 COVID-19 infection COVID-19 infections COVID-19 patient COVID-19 patients cut-off determine Disease progression enrolled eosinophil evaluate the effect ferritin Future hospitalisation hospitalised IgE immune Immunoglobulin independent predictors individual inflammatory parameter males Negative predictive value outcome pandemic parameter Patient patients pilot study Positive predictive value predisposition prognostic biomarker Prognostic factor progression required resource risk factor sensitivity serum severity significantly lower specificity to define total IgE. were measured were recorded with COVID-19 worsened worsening [DOI] 10.1111/imj.15728 PMC 바로가기
Humoral response among patients with interstitial lung disease vaccinated with the BNT162b2 SARS-Cov-2 vaccine: a prospective cohort studyObservational Study Published on 2022-09-012022-10-05 Journal: Respiratory Research [Category] SARS, 임상, 진단, [키워드] addition age and sex Anti-inflammatory Anti-inflammatory therapy anti-inflammatory treatments Anti-spike antibody Antibody titer antifibrotic therapy BNT162b2 BNT162b2 vaccine caused Cohort conducted control group dose evaluate evaluated healthy control high risk humoral Humoral response ILD immune response Immunosuppression Interstitial lung disease IPF maintain median Messenger RNA Patient patients patients treated patients with ILD prospective cohort study pulmonary fibrosis Rabin Medical Center SARS-CoV-2 vaccine serology test seronegative seropositive Severe COVID-19 Infection significantly lower the healthy therapy treated Treatment vaccination vaccine dose was reduced [DOI] 10.1186/s12931-022-02155-x PMC 바로가기 [Article Type] Observational Study
Treatment with stimulants and the risk of COVID-19 complications in adults with ADHDResearch article Published on 2022-09-012022-10-05 Journal: Brain research bulletin [Category] 진단, 치료법, [키워드] 30-Day mortality ADHD association Cohort Complication COVID COVID-19 Critical care database death demographics diagnosed with COVID-19 diagnoses disorder Electronic health record Health hospital hyperactivity Infection infection rate intensive care less medication mental health conditions mitigate multiple logistic regression outcome outcomes Patient Prescription stimulants Research retrospective cohort study risk risk of COVID-19 severe COVID-19 shown significantly lower Stimulant Substance use disorder Treatment [DOI] 10.1016/j.brainresbull.2022.07.005 [Article Type] Research article
Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron SurgeArticle Published on 2022-09-012022-10-06 Journal: The New England Journal of Medicine [Category] SARS, 변종, 진단, 치료제, [키워드] 95% CI 95% confidence interval acute respiratory syndrome adjusted hazard ratio Adults age association B.1.1.529 B.1.617.2 benefit conditions coronavirus covariate death Effectiveness Efficacy eligibility criteria eligible Hospitalization Nirmatrelvir no evidence of Older omicron outcome Patient Protease inhibitor receive Regression model SARS-CoV-2 SARS-CoV-2 immunity service severe coronavirus disease shown significantly lower sociodemographic factors study period therapy treated patient Treatment untreated patient variant was used were assessed [DOI] 10.1056/NEJMoa2204919 PMC 바로가기 [Article Type] Article
Audiological profile of adult Long COVID patientsArticle Published on 2022-09-012022-11-16 Journal: American journal of otolaryngology [Category] SARS, 치료기술, [키워드] clinically control group COVID COVID patient Covid patients COVID-19 ear Emissions Evidence examined frequencies Frequency groups Health Hearing hearing loss large cohort left ear Long Long COVID material no significant difference not significantly different participant persistence reported respondent right ear SARS-CoV-2 SARS-COV-2 infection self-reported symptom significant difference significantly significantly lower Symptom Symptoms tested three group threshold were excluded [DOI] 10.1016/j.amjoto.2022.103579 PMC 바로가기
Antibody Response to SARS-CoV-2 Vaccines in People with Severe Obesity중증 비만 환자의 SARS-CoV-2 백신에 대한 항체 반응Article Published on 2022-09-012022-09-11 Journal: Obesity surgery [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] age antibody antibody level antibody levels Antibody Response Antibody titer Antibody titers anticipated Antigen blood sample Blood samples BMI BNT162b2 BNT162b2 mRNA BNT162b2 vaccine BNT162b2 vaccines consecutive patient Control control group CoronaVac Course COVID-19 COVID-19 vaccination determined by disease domain dose dose of vaccination Effectiveness enrolled female IgG antibody IgG antibody titers inactivated individual Infection information male mRNA normal weight not significantly different obesity of BNT162b2 Patient presenting Quantitative recruited reduced response SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibody SARS-COV-2 infection SARS-CoV-2 spike antigen SARS-CoV-2 vaccination SARS-CoV-2 vaccine serological Severe obesity significantly significantly higher significantly lower spike-protein subject vaccination Vaccine Vaccines vulnerable population was performed weight control were measured [DOI] 10.1007/s11695-022-06181-y PMC 바로가기 [Article Type] Article
Contributing factors to pediatric COVID-19 and MIS-C during the initial waves: A systematic review of 92 case reportsReview article Published on 2022-09-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 변종, 진단, 치료기술, [키워드] addition age baseline Case report children Co-infection community transmission conducted Contributing factors coronavirus disease COVID-19 COVID-19 patients Critical database deficiency demographic characteristics Factor feces G6PD genetic defect group identify infancy Infection initial male management MIS-C pandemic Patient patients pediatric Pediatric patient performed platform Result SARS-CoV-2 School searched shown significantly lower susceptible systematic review the mean the patient Transmission vaccination [DOI] 10.1016/j.amsu.2022.104227 [Article Type] Review article