Acquired insights from the long-term surveillance of SARS-CoV-2 RNA for COVID-19 monitoring: The case of Monterrey Metropolitan Area (Mexico)COVID-19 모니터링을 위한 SARS-CoV-2 RNA의 장기 감시에서 얻은 통찰력: 몬테레이 수도권(멕시코) 사례Article Published on 2022-07-012022-09-11 Journal: Environmental research [Category] COVID19(2023년), SARS, 치료기술, [키워드] Acquired Analysis applicability applied approach Area clinical testing Community complement COVID-19 demonstrated detection rate epidemiological Epidemiology estimate feasible hospital Improvements Interpretation median MONITOR offer outbreak plant positive Prevalence ranged reported Result room RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 viral load SARS-CoV-2 viral loads Spread statistical Surveillance tested Treatment Viral load viral titer viral titers wastewater [DOI] 10.1016/j.envres.2022.112967 PMC 바로가기 [Article Type] Article
A machine learning-based approach to determine infection status in recipients of BBV152 (Covaxin) whole-virion inactivated SARS-CoV-2 vaccine for serological surveys혈청학적 조사를 위한 BBV152(Covaxin) 전체 비리온 비활성화 SARS-CoV-2 백신의 수혜자의 감염 상태를 결정하기 위한 기계 학습 기반 접근 방식Article Published on 2022-07-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 치료법, [키워드] age antibody antigens applied approach assessment assessments BBV152 Breakthrough infection can be used Clustering Consensus Covaxin COVID-19 COVID-19 pandemic Data science dataset Delta determine dose doses effective Effectiveness Ensemble methods generate help immune response inactivated Infection machine machine learning ML model neutralization Neutralization assay neutralize nucleocapsid antigens Population predicted premise Protein random recipient recipients SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine sequence sequences serological survey Sex spike Spike protein statistical subject subjects subset Support the vaccine type strain uninfected Vaccine vaccine response viral evolution Viral proteins virion wild type wild-type strain [DOI] 10.1016/j.compbiomed.2022.105419 PMC 바로가기 [Article Type] Article
Ligand-based and structure-based studies to develop predictive models for SARS-CoV-2 main protease inhibitors through the 3d-qsar.com portal3d-qsar.com 포털을 통해 SARS-CoV-2 주요 프로테아제 억제제에 대한 예측 모델을 개발하기 위한 리간드 기반 및 구조 기반 연구Article Published on 2022-07-012022-09-11 Journal: Journal of computer-aided molecular design [Category] COVID19(2023년), SARS, 치료제, [키워드] 3-D QSAR Analysis applicability approach binding binding energy build calculation Candidates cleavage site co-crystallized Combination COMBINE Compound conservation coronavirus COVID-19 infected patients develop domain drug design Emergency use authorization enzyme EUA feature Final functional protein implicated in viral inhibitor inhibitors joint Ligand ligand-based drug design M pro maturation Metrics Mild-to-moderate Model molecular Nirmatrelvir outcome performed portal Predictive Predictive model promote protease Quantitative reached Replication reported resources robust robustness safety profile SARS-CoV-2 SARS-CoV-2 main protease statistical Structure-activity relationships Structure-based drug design tolerable training set Transcription Treatment U.S. FDA viral replication Virtual screening [DOI] 10.1007/s10822-022-00460-7 PMC 바로가기 [Article Type] Article
Machine learning approach for automated predicting of COVID-19 severity based on clinical and paraclinical characteristics: Serum levels of zinc, calcium, and vitamin DResearch article Published on 2022-07-012022-10-05 Journal: Clinical nutrition ESPEN [Category] 임상, [키워드] Accuracy age Algorithm Algorithms anorexia approach AUC automated Automated prediction blood sample can be used cardiovascular disease Characteristics conducted correlation COVID-19 COVID-19 severity cross-sectional data set decision develop disease severity disease symptoms Factor FBS feature forest Gender indicated investigated machine machine learning novel coronavirus disease outcome parameter Patient Precision Predictive model recall Result Serum level Severe case severity Standard therapy statistical support vector machine SVM Treatment tree [DOI] 10.1016/j.clnesp.2022.07.011 [Article Type] Research article
Automated diagnosis of COVID stages from lung CT images using statistical features in 2-dimensional flexible analytic wavelet transformResearch article Published on 2022-07-012022-10-05 Journal: Biocybernetics and Biomedical Engineering [Category] 치료기술, [키워드] Accuracy Algorithm applied approach assist chest imaging chest X-ray Computed tomography contagious COVID COVID-19 COVID-19 epidemic CT scan demonstrated detect diagnosed Diagnosis early stage FAWT based image decomposition feature Feature extraction Features flexible help identify illnesses image classification lung Lung CT machine learning Medical imaging outcomes PCA physical principal component analysis problems progression Respiratory system robust sensitivity specificity Spread Stage statistical student two-dimensional venous virus X-ray [DOI] 10.1016/j.bbe.2022.06.005 [Article Type] Research article
Exposing and Overcoming Limitations of Clinical Laboratory Tests in COVID-19 by Adding Immunological Parameters; A Retrospective Cohort Analysis and Pilot Study면역학적 매개변수를 추가하여 COVID-19에서 임상 실험실 테스트의 한계를 노출하고 극복합니다. 후향적 코호트 분석 및 파일럿 연구Article Published on 2022-06-292022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] acute phase acute phase reactants Adding adopted age Alanine alanine aminotransferase Algorithm Analysis aspartate Aspartate aminotransferase association Barcelona best Biomarker C-reactive protein category CCL2 chemokines classical clinical clinical and laboratory variables clinical laboratories clinical laboratory clinical laboratory tests Clinical management clinical parameter Clinical parameters clinical variable clinical variables Cohort collected Comorbidity conducted COVID 19 patient COVID 19 patients COVID-19 COVID-19 pandemic COVID-19 patient CXCL10 cytokine Cytokines exploratory feasible fibrinogen filtration rate First wave flow cytometry fraction glomerular filtration rate IL-1ra IL-6 immune response immunological Immunological test immunological tests IMPROVE independent Inflammation Interpretation Laboratory Laboratory test Laboratory tests limitation lymphocyte neutrophil organ organ damage outcome overcome oxygen oxygen saturation pandemic patients performed phenotype pilot study Predictive predictive power predictive risk-profile. predictor Prognosis redundancy reflected SARS-CoV-2 SARS-COV-2 infection severity statistical statistical analysis survival Test two subgroup two subgroups understanding validation cohort validation cohorts variable [DOI] 10.3389/fimmu.2022.902837 PMC 바로가기 [Article Type] Article
Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis2021년 11월 14일까지 SARS-CoV-2의 전 세계, 지역 및 국가 일일 및 누적 감염 추정: 통계 분석Article Published on 2022-06-252022-09-11 Journal: Lancet (London, England) [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] accounted adjusted Analysis antibody approach Asia assumption available data B.1.1.529 Baltimore calculated Complete country COVID-19 COVID-19 research cumulative database death deaths determinant determinants distribution effective estimate excess mortality foundation future infection help herd immunity Herd immunity threshold highest Hospital admissions hospitalisation hospitalisations identify IFR IHR Immunity India individual individuals Infection infection rate infection rates infections infectious infectiousness information Johns Hopkins Johns Hopkins University location lowest Melinda Gate Melinda Gates Mortality National occurred Oceania pandemic parameter peaking per day Population predict predictor produced proportion Reinfection reported Reporting reproductive responses risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sensitivity seroprevalence survey Seven statistical statistical analysis statistical model sub-Saharan Africa susceptibility systematic reviews These data transmission patterns USA Vaccinations Vaccine variant variants [DOI] 10.1016/S0140-6736(22)00484-6 PMC 바로가기 [Article Type] Article
Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children소아에서 SARS-CoV-2 감염에 대한 효과적인 고처리량 RT-qPCR 스크리닝Article Published on 2022-06-252022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] Alpha Alpha variant approach children class correlated delta variant Deprivation diagnosed effective Frequency Germany incidence indicated individual Infection infection control Local Non-invasive positive powerful tool RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 surveillance SARS-CoV-2 testing School Schools sensitivities sensitivity statistical Support Surveillance tested variant Viral load viral loads [DOI] 10.1038/s41467-022-30664-2 PMC 바로가기 [Article Type] Article
Discovering potential interactions between rare diseases and COVID-19 by combining mechanistic models of viral infection with statistical modeling바이러스 감염의 기계론적 모델과 통계적 모델링을 결합하여 희귀 질환과 COVID-19 간의 잠재적 상호 작용 발견Article Published on 2022-06-222022-09-11 Journal: Human molecular genetics [Category] 유전자 메커니즘, 치료기술, [키워드] analyzed approach consequence Consequences coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 disease COVID-19 infection demonstrated described detect disease downstream genetic component genetic variability hallmark host genetics identify in some infection process Interaction loss of function mathematical mechanism molecular Molecular Disease MOST occur pathological consequences preventive measure Prognosis rare disease rare diseases recent statistical systematic analysis viral infection with COVID-19 [DOI] 10.1093/hmg/ddac007 PMC 바로가기 [Article Type] Article
Isolating the net effect of multiple government interventions with an extended Susceptible-Exposed-Infectious-Recovered (SEIR) framework: empirical evidence from the second wave of COVID-19 pandemic in China확장된 SEIR(Susceptible-Exposed-Infectious-Recovered) 프레임워크로 여러 정부 개입의 순 효과 분리: 중국의 COVID-19 대유행의 두 번째 물결에 대한 경험적 증거Article Published on 2022-06-202022-09-11 Journal: BMJ Open [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] approach China closure component COVID-19 COVID-19 pandemic data extraction data-driven Disinfection eligibility eligibility criteria Endemic epidemiological epidemiological data Epidemiology Evidence FIVE Government Health Health policy implementation Implications indicated information Intervention introduced investigated Isolating Local local outbreak local outbreaks MALL Masks nine outbreak pandemic partial lockdown pathway public health Research restaurant second wave SEIR significantly statistical synthesis tracing Transmission [DOI] 10.1136/bmjopen-2022-060996 PMC 바로가기 [Article Type] Article