statistically – Page 7 – Communicable Diseases Research

Specific Antibody and the T-Cell Response Elicited by BNT162b2 Boosting After Two ChAdOx1 nCoV-19 in Common Variable Immunodeficiency

공통 가변성 면역 결핍증에서 2개의 ChAdOx1 nCoV-19 후 BNT162b2 부스팅에 의해 유도된 특정 항체 및 T-세포 반응

Article

Published on 2022-06-172022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술,

Digital teaching tools in sports medicine: A randomized control trial comparing the effectiveness of virtual seminar and virtual fishbowl teaching method in medical students

Randomized Controlled Trial

Published on 2022-06-162022-10-05
Journal: PLoS ONE [Category] 임상,

[키워드] Course COVID-19 pandemic Digital Effectiveness groups imperative IMPROVE involved knowledge Medicine MOST participated promote Randomized sport statistically subject transfer Trial
[DOI] 10.1371/journal.pone.0267144 PMC 바로가기 [Article Type] Randomized Controlled Trial

Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial

Clinical Trial

Published on 2022-06-072022-10-05
Journal: The Lancet. Respiratory Medicine [Category] COVID19(2023년), SARS, 임상, 진단, 치료법, 치료제,

[키워드] 1:1 95% CI administration Adverse age Antigen assigned AstraZeneca block sizes blocked clinical clinical evaluation clinically collected conducted Course COVID-19 COVID-19 vaccination death dose double-blind Efficacy enrolled enrolment Europe evaluate event Fever finding for inclusion funding individual intramuscular intramuscular injections investigators involved Japan laboratory-confirmed SARS-CoV-2 infection Latin America less Mild moderate Moderate COVID-19 monoclonal antibody combination non-hospitalised occurred Older outcomes participant Phase 3 Placebo placebo-controlled study placebo-controlled trial prevent disease progression primary endpoint progression provided randomisation randomised Randomly receive Registered required respiratory tract risk reduction RT-PCR scale severe COVID-19 severity specimen Sponsor statistically stratified study drug Symptom symptom onset the disease the placebo group treating Treatment treatment group USA WHO
[DOI] 10.1016/S2213-2600(22)00180-1 [Article Type] Clinical Trial

Clinical Characteristics and Risk Factors for Mortality in Critical Coronavirus Disease 2019 Patients 50 Years of Age or Younger During the Delta Wave: Comparison With Patients > 50 Years in Korea

2019년 델타파 중 50세 이하 환자 중대 코로나바이러스 감염증의 임상적 특성 및 사망률 위험인자: 국내 50세 이상 환자와의 비교

Article

Published on 2022-06-062022-09-11
Journal: Journal of Korean medical science [Category] COVID19(2023년), SARS, 변종,

[키워드] 95% CI 95% confidence interval Adult patients age analyses Analysis analyzed Blood stream infection BMI body mass body mass index Case fatality rate clinical Clinical characteristics clinical feature Clinical features condition conditions coronavirus disease Coronavirus disease 2019 COVID-19 creatinine Critical critical condition death Delta delta variant diabetes Diabetes Mellitus died dominant eight electronic medical record enrolled evaluate Factor Fatality rate General population globe highest highlight hospital Hospitalized hypertension identify independent predictor independent predictors Infection measure mechanical ventilation Mortality mortality risk factor mortality risk factors Multivariate analysis nasal nasal cannula Numerous obese obesity Odds ratio Older older patient older patients oxygen Oxygen therapy Patient PCR-confirmed COVID-19 Prevent progression respiratory Respiratory Support risk risk factor Risk factors Secondary infection severity statistically study period study population the patient therapy total patients underlying disease vaccination vaccination rate Vaccinations variant while women Year Young younger patient younger patients
[DOI] 10.3346/jkms.2022.37.e175 PMC 바로가기 [Article Type] Article

Favipiravir, camostat, and ciclesonide combination therapy in patients with moderate COVID-19 pneumonia with/without oxygen therapy: An open-label, single-center phase 3 randomized clinical trial

Research article

Published on 2022-06-032022-10-05
Journal: EClinicalMedicine [Category] 신약개발, 임상, 치료제,

[키워드] 95% CI Admission Adverse AMED assigned calculated camostat Characteristics Ciclesonide clinical Clinical finding Clinical management Combination combination therapy comparable COVID-19 COVID-19 infection deaths decrease development discharge Effectiveness enrolled evaluated event Favipiravir finding funding group groups healthcare worker hospital discharge rate Hospital stay Hospitalization Hospitalized Japan Japanese lack less limitation median time Ministry of Health monotherapy no significant difference number Open-label oxygen participant Patient patients patients with moderate Phase 3 phase 3 study Pneumonia positive Primary outcome randomized clinical trial Randomized controlled trial Randomly Registered registry Research SARS-CoV-2 Severe COVID-19 Infection significantly higher significantly lower single-center statistically supported therapy Treatment vaccination Version Welfare
[DOI] 10.1016/j.eclinm.2022.101484 [Article Type] Research article

Concordance in RT-PCR detection of SARS-CoV-2 between samples preserved in viral and bacterial transport medium

바이러스 및 박테리아 수송 배지에 보존된 샘플 간의 SARS-CoV-2 RT-PCR 검출 일치

Article

Published on 2022-06-012022-09-11
Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, 치료제,

[키워드] All participants analyzed Bacteria Bacterial calculated collected Community Concordance Ct values cycle threshold determine Diagnostic method Glucose Glycerin in viral independent independent of longitudinal cohort study medium nasal nasal swab nasal swabs nasopharyngeal Nasopharyngeal swab NP swab NP swabs ORF1 ORF1ab participant Pathogens preserved real time respiratory pathogen respiratory symptoms RT-PCR RT-PCR detection Sample SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 infections skim milk specimen statistically Swab swabs targets Transport Transport media transport medium tryptone Viral transport medium VTM was used while
[DOI] 10.1016/j.jviromet.2022.114522 PMC 바로가기 [Article Type] Article

Anakinra treatment efficacy in reduction of inflammatory biomarkers in COVID-19 patients: A meta-analysis

COVID-19 환자에서 염증성 바이오마커 감소에 대한 아나킨라 치료 효능: 메타 분석

Meta-Analysis

Published on 2022-06-012022-09-11
Journal: Journal of Clinical Laboratory Analysis [Category] COVID19(2023년), SARS, 바이오마커,

[키워드] acute-phase reactant Admission Anakinra analyzed anti-inflammatory agent C-reactive protein C-reactive protein (CRP Care Cochrane Central concentrations conducted COVID-19 COVID-19 patients CRP CRP value CRP values D-dimer database dimer Efficacy elevated ferritin Follow-up hematological Inflammatory Inflammatory biomarker inflammatory biomarkers interleukin interleukin-1 Laboratory males Manger marker mean difference mean value Meta-analysis notable Patient Protein reduce mortality reduced reduction review SARS-CoV-2 serum Serum ferritin SMD statistically the mean Treatment treatment of COVID-19 patients trials Web of Science
[DOI] 10.1002/jcla.24434 PMC 바로가기 [Article Type] Meta-Analysis

Monitoring of alcohol-based hand rubs in SARS-CoV-2 prevention by HS-GC/MS and electrochemical biosensor: A survey of commercial samples

HS-GC/MS 및 전기화학적 바이오센서에 의한 SARS-CoV-2 예방의 알코올 기반 손 문지름 모니터링: 상업용 샘플 조사

Article

Published on 2022-05-302022-09-11
Journal: Journal of pharmaceutical and biomedical analysis [Category] COVID19(2023년), SARS, 치료기술,

[키워드] acidification addition agency alcohol Alcohol-based hand rubs alignment ANOVA ANOVA test approach average Chromatography comparable Control coronavirus 2 correlation COVID-19 data set determine diffusion electrochemical biosensor ethyl alcohol evaluated gas chromatography Gas chromatography. hand hygiene Health highlighting house hygiene identify indicated indication indications isopropyl alcohol limit limit of detection LoQ mass mass spectrometry methyl alcohol monitoring parameter propyl alcohol provided quantification reported respiratory Result SARS-CoV-2 screening method severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spectrometry statistically tested were assessed widespread
[DOI] 10.1016/j.jpba.2022.114694 PMC 바로가기 [Article Type] Article

Differences in SARS-CoV-2-Specific Antibody Responses After the First, Second, and Third Doses of BNT162b2 in Naïve and Previously Infected Individuals: A 1-Year Observational Study in Healthcare Professionals

BNT162b2 1차, 2차, 3차 접종 후 SARS-CoV-2 특이 항체 반응의 차이

Observational Study

Published on 2022-05-272022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료법,

[키워드] addition age Analysis Anti-nucleocapsid antibodies anti-nucleocapsid antibody anti-S anti-S antibody anti-S antibody dynamics Anti-spike antibody concentration BMI BNT162b2 BNT162b2 vaccine booster Concentration concentrations COVID-19 Critical determine difference different time point dose doses effective vaccine Effective vaccines first dose hcp healthcare Healthcare professional healthcare professionals humoral immune response humoral immune responses immune responses increase in individual infected individual infected individuals Infection median median value naïve naïve individual naïve individuals of BNT162b2 omicron predictor professional Protective response Safe SARS-CoV-2 second second dose sera Sex significant difference significant differences significantly Spread statistically steadily decreased systemic adverse event systemic adverse events vaccination vaccination schedule Vaccine variant variants of SARS-CoV-2 were used
[DOI] 10.3389/fimmu.2022.876533 PMC 바로가기 [Article Type] Observational Study

Telemedicine diagnosis of acute respiratory tract infection patients is not inferior to face-to-face consultation: a randomized trial

Randomized Controlled Trial

Published on 2022-05-272022-10-05
Journal: Einstein [Category] 임상,