Antibody levels after BNT162b2 vaccine booster and SARS-CoV-2 Omicron infectionArticle Published on 2022-09-162022-11-15 Journal: Vaccine [Category] SARS, 변종, 진단, [키워드] administration antibody antibody level Antibody Response BNT162b2 vaccine booster booster dose booster vaccination COVID-19 decrease Delta evaluated HCW HCWs healthcare worker humoral immune response immune immunisation Immunisation safety Immunity immunogenicity data increase in Infection much higher naïve Neutralizing antibodies of BNT162b2 omicron Omicron variant resulting SARS-CoV-2 second dose second vaccination severe symptoms Support the vaccine threshold Vaccine variant virus [DOI] 10.1016/j.vaccine.2022.08.045 PMC 바로가기
Antibody titers among healthcare workers for coronavirus disease 2019 at 6 months after BNT162b2 vaccinationArticle Published on 2022-09-162022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] acute respiratory syndrome age Analysis analyzed Anti-spike antibody antibody level Antibody titre BNT162b2 BNT162b2 vaccine Care conducted coronavirus disease coronavirus disease-2019 Coronavirus-2 COVID-19 decrease dose Factor female females healthcare healthcare worker Healthcare workers hospital IgG IgG antibody Japanese negative correlation participant Participants preserved Prospective Study Protein Regression SARS-CoV-2 side Side effects tested the vaccine vaccination were infected [DOI] 10.1016/j.vaccine.2022.08.035 PMC 바로가기
A quick scoping review of the first year of vaccination against the COVID-19 pandemic: Do we need more shots or time?Article Published on 2022-09-162022-11-15 Journal: Medicine [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome Adequate administration benefit booster booster dose booster vaccinations Breakthrough infection conducted coronavirus coronavirus disease COVID-19 COVID-19 vaccination COVID-19 vaccine debates demonstrated dose Effect ENhance Evidence General population healthcare Immunity Immunocompromised patient individuals information Initially lack maintain neutralizing antibody pandemic raised reported required Safe second dose the vaccine trajectory vaccination Vaccine Vaccine-induced immunity variants Viral variants waning immunity [DOI] 10.1097/MD.0000000000030609 PMC 바로가기
Loss of Pfizer (BNT162b2) Vaccine-Induced Antibody Responses against the SARS-CoV-2 Omicron Variant in Adolescents and AdultsArticle Published on 2022-09-142022-11-15 Journal: Journal of Virology [Category] SARS, 변종, 진단, [키워드] Adolescent adolescents adolescents and adult adolescents and adults Adults age antibody Antibody binding antibody binding titers approved Beta binding binding antibody BNT162b2 BNT162b2 vaccine booster booster dose booster vaccination breadth changes in children circulating clinical trial Cohort Coverage COVID-19 Delta demonstrated dose drug Effectiveness Efficacy evaluate FDA food Gamma highlight Hospitalization humoral immune response lack less Loss magnitude mounted mRNA vaccine neutralization Neutralizing antibody response omicron Omicron (B.1.1.529) pandemic pediatric Pfizer Pfizer-BioNTech Pfizer-BioNTech (BNT162b2) plasma populations PROTECT reduction reported Research response responses against robust SARS-CoV-2 seasonal beta coronavirus the antibody response the SARS-CoV-2 the vaccine vaccination Vaccine vaccine-induced antibody response Vaccine-induced immunity variant variant of concerns (VOCs) variants viral variant Virus neutralization virus spike protein VoC VOCs while wild-type SARS-CoV-2 [DOI] 10.1128/jvi.00582-22 PMC 바로가기
SARS-CoV-2 specific T cell and humoral immune responses upon vaccination with BNT162b2: a 9 months longitudinal studyArticle Published on 2022-09-142022-11-15 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome BNT162b2 vaccine booster dose Cellular immune response changes in conducted coronavirus coronavirus disease COVID-19 demonstrated dose first vaccination follow-up period highest hospital humoral humoral immune response IgG IgG antibody immune response neutralization Neutralizing activity neutralizing antibody no correlation performed receiving SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 spike second vaccination serological Seven significantly sustained T cell T cell assay T cell response T cell responses the vaccine vaccination [DOI] 10.1038/s41598-022-19581-y PMC 바로가기
Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With MyelomaArticle Published on 2022-09-102022-11-15 Journal: Journal of clinical oncology : official journal of [Category] SARS, 변종, 진단, 치료기술, [키워드] affected analyzed antibody B-cell malignancy BNT162b2 Booster vaccine Characteristics Critical Delta detect detectable determinant disease environmental exposure Factors greater hosts Immunocompromised implication increased risk induction initial lack Live virus Moderna MONITOR Mortality mRNA1273 much lower Multiple myeloma Myeloma NAb neutralization neutralize neutralizing antibody neutralizing capacity nucleocapsid Patient patients Pseudovirus neutralization assay quantified RBD receiving response SARS CoV-2 Seroconversion Serologic response significantly spike receptor-binding domain the vaccine Treatment vaccination Vaccine vaccine-induced antibody variant viral neutralization virus virus-neutralizing were measured [DOI] 10.1200/JCO.21.02257 PMC 바로가기
mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cellsArticle Published on 2022-09-072022-11-16 Journal: Molecular therapy : the journal of the American So [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] antibody antigen-presenting cells appear B cell biodistribution Cancer Cancer vaccine CD8 T cell changes in Clinical studies design-of-experiments methodology effective extrahepatic delivery histopathological Immune cell immune cell populations Immunity immunization Immunotherapy induce interferon liver LNP mechanism methodology mRNA mRNA expression non-human primate phagocyte provide response responses SARS-CoV-2 spleen stimulatory systemic T cell T cell response the vaccine Type vaccination Vaccine [DOI] 10.1016/j.ymthe.2022.07.007 PMC 바로가기
SARS CoV- 2 vaccination induces antibodies against cardiolipinArticle Published on 2022-09-072022-11-15 Journal: BMC Research Notes [Category] SARS, 진단, [키워드] administration antibody BNT162b2 ChAdOx1-S clinically Coagulopathies Concentration controls COVID-19 COVID-19 negative different time point ELISA evaluate evaluated group highest IgG antibody individual individuals induce Oxford-AstraZeneca pathogenic Pfizer positive positive individual raised reported risk Sample SARS CoV SARS-COV-2 infection SARS-CoV-2 vaccines second dose serum significant difference the vaccine thrombosis vaccination venous was measured [DOI] 10.1186/s13104-022-06180-3 PMC 바로가기
Long-term memory CD8+ T cells specific for SARS-CoV-2 in individuals who received the BNT162b2 mRNA vaccineArticle Published on 2022-09-062022-11-16 Journal: Nature Communications [Category] SARS, 변종, 치료기술, [키워드] Analysis analyzed BNT162b2 mRNA vaccine CD8 CD8+ T cell conserved COVID-19 vaccine detectable Efficacy epitope Epitopes evaluate help high affinity high stability HLA-A*24:02 immunized immunodominant epitope individual induce infection with SARS-CoV-2 long-term memory memory T cell peptide populations Prevent recognize SARS-CoV-2 SARS-CoV-2 variants second vaccination T cell T cell receptor the vaccine Vaccine variants [DOI] 10.1038/s41467-022-32989-4 PMC 바로가기
Relative Effectiveness of COVID-19 Vaccination in Healthcare Workers: 3-Dose Versus 2-Dose VaccinationArticle Published on 2022-09-052022-11-16 Journal: Journal of Korean medical science [Category] SARS, 변종, [키워드] 1:1 acute respiratory syndrome Analysis booster booster vaccination case-control study conducted controls coronavirus COVID-19 cross-reactive dose Effectiveness elapsed evade evaluate expected healthcare worker Immunity moderate mRNA vaccine Omicron variant positive relative SARS-CoV-2 SARS-CoV-2 test the vaccine vaccination vaccine effectiveness vaccine immunity [DOI] 10.3346/jkms.2022.37.e267 PMC 바로가기