Characterization of Serum and Mucosal SARS-CoV-2-Antibodies in HIV-1-Infected Subjects after BNT162b2 mRNA Vaccination or SARS-CoV-2 InfectionBNT162b2 mRNA 백신 접종 또는 SARS-CoV-2 감염 후 HIV-1 감염 대상에서 혈청 및 점막 SARS-CoV-2-항체의 특성화Article Published on 2022-03-212022-09-11 Journal: Viruses [Category] SARS, 치료기술, [키워드] all subject all subjects analysed Anti-spike anti-Spike IgG antibody Antiretroviral therapy BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccine characterization convalescent detectable dose ELISA Frequency HIV-1 humoral humoral immune response IgA IgA antibodies IgA antibody IgG immune Immunity immunogenicity indicate induce investigated mRNA vaccination mRNA vaccine mucosal mucosal immunity neutralization activity Neutralization assay Neutralizing activity Neutralizing antibodies neutralizing antibody neutralizing capacity no significant difference of BNT162b2 Patient patients Saliva saliva samples SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike-specific SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody serum serum levels significantly higher significantly lower specific antibodies spike IgA spike-specific antibody response subject subjects uninfected vaccination Vaccine vaccine response vaccinee vaccinees while [DOI] 10.3390/v14030651 PMC 바로가기 [Article Type] Article
Evaluating the antibody response to SARS-COV-2 vaccination amongst kidney transplant recipients at a single nephrology centre단일 신장 센터에서 신장 이식 수혜자의 SARS-COV-2 백신 접종에 대한 항체 반응 평가Research Article Published on 2022-03-102022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Allograft Analysis antibody Antibody Response Antibody testing appear AZD1222 benefit BNT162b2 Cohort coronavirus Corticosteroid death deaths dose Effectiveness EGFR evaluated Evaluating Final final analysis General population glomerular filtration greater identify Immunosuppression increasing age Infection infections kidney transplant recipient kidney transplant recipients maintenance multivariate mycophenolic acid non-responder non-responders occurred Oxford-AstraZeneca participant Participants Patient performed Pfizer Pfizer-BioNTech pre-vaccination predictor Primary outcome randomized trials recipient Responder responders Result SARS-CoV-2 antibody testing SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 vaccine SARS-CoV-2 vaccines serious complication seroconversion rate seroconversion rates seropositive severe acute respiratory syndrome Coronavirus significantly single center the antibody response Treatment United Kingdom vaccination Vaccine vaccine doses vaccine response Vaccines variable were excluded were recorded [DOI] 10.1371/journal.pone.0265130 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 vaccination elicits unconventional IgM specific responses in naïve and previously COVID-19-infected individualsSARS-CoV-2 예방 접종은 순진하고 이전에 COVID-19에 감염된 개인에서 비전통적인 IgM 특이적 반응을 이끌어냅니다.Article Published on 2022-03-012022-09-12 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] administration anti-S antibody BNT162b2 vaccine BTN162b2 vaccine Care Cohort collected coronavirus COVID-19 cross Department elicit expression foundation HCW Health IgG IgG antibody IgM IgM antibody Immunity immunologically individual Infection Italian Limited Ministry of Health naïve neutralization performed positive Protein pseudovirus recipient recruitment response Sample SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 vaccination second dose sera significantly more spike the SARS-CoV-2 titre titres vaccination vaccine dose vaccine response Verona virus-neutralizing [DOI] 10.1016/j.ebiom.2022.103888 PMC 바로가기 [Article Type] Article
Cellular and humoral responses to SARS-CoV-2 vaccination in immunosuppressed patients면역 억제 환자에서 SARS-CoV-2 백신 접종에 대한 세포 및 체액 반응Article Published on 2022-03-012022-09-11 Journal: Cellular immunology [Category] SARS, 치료기술, [키워드] Activation anti-spike antibodies B-cell BNT162b2 BNT162b2 mRNA CD8 ChAdOx1 ChAdOx1 nCoV-19 cohorts comparable COVID-19 cytokine Cytokines demonstrated depleting detectable difference Efficacy elicited haematological malignancies haematological malignancy healthy healthy volunteers highest Humoral response humoral responses immunodominance immunogenic immunological responses Immunophenotyping Immunosuppressed immunosuppressed patient immunosuppressed patients Immunosuppression immunosuppressive immunosuppressive therapy less Longevity Lower memory naïve no significant differences non-responder participant Participants Patient patients treated phenotype preserved protective immunity receiving renal responders response SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines seroconvert serological seropositive Seropositivity significant difference T-cell T-cell ELISpot T-cell Response T-cell responses Th1 cytokine therapy Transplant Vaccinations vaccine immunogenicity vaccine response vaccine responses were used [DOI] 10.1016/j.cellimm.2022.104501 PMC 바로가기 [Article Type] Article
Haematopoietic stem cell transplant patients have a high initial failure rate to hepatitis B vaccination that can be overcome with subsequent vaccination seriesArticle Published on 2022-03-012023-06-11 Journal: British Journal of Haematology [Category] B형 간염, [키워드] Allogeneic stem cell transplantation hepatitis B Immunity vaccination vaccine response [DOI] 10.1111/bjh.17991
COVID-19 vaccination in cancer patients: a narrative review암 환자의 COVID-19 예방 접종: 내러티브 검토Review Published on 2022-03-012022-09-12 Journal: The Journal of international medical research [Category] MERS, SARS, 진단, [키워드] active cancer acute respiratory syndrome adverse effect affected article Cancer caused cell-mediated immune response comparable coronavirus Coronavirus disease 2019 COVID COVID-19 COVID-19 vaccination COVID-19 vaccine database disease severity Effectiveness Factor Google Scholar haematological malignancies healthy individuals humoral humoral immune response immunogenicity in healthy individuals individual interval investigated knowledge morbidity and mortality Mortality Patient Patients with cancer profile reducing SARS-CoV-2 second dose shown solid cancers solid malignancies vaccination Vaccine vaccine dose vaccine effectiveness vaccine response vaccine safety Vaccines [DOI] 10.1177/03000605221086155 PMC 바로가기 [Article Type] Review
Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses Reviews Published on 2022-02-242022-10-05 Journal: Nature Immunology [Category] COVID19(2023년), SARS, 비임상, [키워드] acute respiratory syndrome Adaptive immune response adaptive immune responses adjuvant age approach cellular contribute coronavirus Coronaviruses effective Efficacy environmental factor Factor failure Fighting Genetic geographical location heterogeneity humoral immune response Humoral immunity immune protection impair innate immune innate immune response innate immune system long-lived plasma cell mechanism memory T cell metabolite microbiome composition MOST pandemic SARS-CoV-2 Sex the SARS-CoV-2 Vaccine vaccine response Vaccines vectors [DOI] 10.1038/s41590-022-01130-4 [Article Type] Reviews
B-cell cytopenia and time to last B-cell-depleting therapy predict response to SARS-COV-2 vaccines in patients with lymphoproliferative disordersB 세포 혈구 감소증 및 B 세포 고갈 요법 지속 시간은 림프 증식성 장애 환자에서 SARS-COV-2 백신에 대한 반응을 예측합니다Article Published on 2022-02-232022-09-12 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Anti-RBD antibody antibody Antibody Response B cell B-cell B-cell cytopenia Cohort controls COVID-19 COVID-19 vaccines depleting dose increased risk investigated lymphocyte lymphoma lymphoproliferative disorder morbidity and mortality NHL observation Patient patients predict raise receiving rituximab SARS-CoV-2 Serologic response the SARS-CoV-2 therapy treated Treatment unlikely Vaccine vaccine response [DOI] 10.1016/j.vaccine.2022.01.040 PMC 바로가기 [Article Type] Article
Decline in Antibody Concentration 6 Months After Two Doses of SARS-CoV-2 BNT162b2 Vaccine in Solid Organ Transplant Recipients and Healthy ControlsSARS-CoV-2 BNT162b2 백신 2회 접종 후 6개월 동안 고형 장기 이식 환자 및 건강한 대조군에서 항체 농도 감소Immunology Published on 2022-02-232022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI acute respiratory syndrome age Anti-RBD IgG anti-receptor-binding domain antibody BNT162b2 Cancer cellular response clinical impact Comorbidity Concentration Control controls Coronavirus-2 Corticosteroid COVID-19 de novo Decline declined determine dose examined Factor first dose first vaccination geometric mean concentration GMC healthy control healthy controls humoral IgG immunogenicity Immunoglobulin indicated kidney lung Month neutralizing capacity of BNT162b2 previous study RBD recipient recipients response Result risk SARS-CoV-2 SARS-CoV-2 BNT162b2 second dose Solid solid organ transplant solid organ transplant recipient SOT T-cell Response Transplant Treatment vaccination Vaccine vaccine response were measured [DOI] 10.3389/fimmu.2022.832501 PMC 바로가기 [Article Type] Immunology
Decline of Humoral Responses 6 Months after Vaccination with BNT162b2 (Pfizer–BioNTech) in Patients on HemodialysisArticle Published on 2022-02-182022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] absence analyzed anti-SARS-CoV-2 IgG antibody association binding binding antibody BNT162b2 chemiluminescent immunoassay Chronic kidney disease CLIA COVID-19 Decline declined dose first vaccination Hemodialysis humoral immune response Humoral response identify immune response infected with SARS-CoV-2 median Month mRNA vaccines multivariable naïve Neutralizing activity Neutralizing antibodies Neutralizing antibody titer Patient Pfizer–BioNTech receiving Regression model response risk risk factor SARS-CoV-2 SARS-CoV-2 IgG Seroconversion seroconversion rate serum albumin spike glycoprotein vaccination vaccination schedule vaccine response vanishing was tested was used were measured wild-type virus [DOI] 10.3390/vaccines10020327 PMC 바로가기 [Article Type] Article