Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease
Article
[키워드] 229E
Activation
acute respiratory syndrome
affected
airway
being
benefit
Calu-3 cell
change
changes in
cleavage
conserved
coronavirus
creating
Critical
Delta
dibasic
experiment
favor
functional
fusion peptide
had no
help
host cell
human coronavirus 229E
humans
immune evasion
immunogenic
Impact
influence
less
MERS-CoV
Middle East
motif
mutant
Mutation
mutations
new SARS-CoV-2
no difference
omicron
pathogenic
protease
Proteases
Protein
pseudovirus
pseudovirus entry
reduced
remained
residue
residues
respiratory syndrome coronavirus
reverse effect
SARS-CoV-2
SARS-CoV-2 spike
sequence
shown
spike
spike functioning
Spike protein
Surveillance
the SARS-CoV-2
TMPRSS13
TMPRSS13 protease
TMPRSS2
Tolerance
variant
variants
Variation
virus entry
Wuhan-Hu-1
[DOI] 10.1128/mbio.01376-22 PMC 바로가기
[DOI] 10.1128/mbio.01376-22 PMC 바로가기