WHO – Page 7 – Communicable Diseases Research

When Virtual Screening Yields Inactive Drugs: Dealing with False Theoretical Friends

Article

Published on 2022-08-172022-11-15
Journal: ChemMedChem [Category] COVID19(2023년), SARS, 신약개발, 치료제,

SARS-CoV-2 antibody progression and neutralizing potential in mild symptomatic COVID-19 patients – a comparative long term post-infection study

Article

Published on 2022-08-172022-11-15
Journal: Frontiers in Immunology [Category] SARS, 진단,

[키워드] acute infections addition Antibody titer block CLIA clinician Cohort comparability comparable convalescent COVID-19 disease COVID-19 patient Cutoff diagnostics ELISA FIVE help immune immune response increasingly individual immune response Infection information Laboratory long-COVID long-term assay comparison Mild mild progression COVID-19 mild SARS-CoV-2 infection Molecular diagnosis neutralization Neutralizing neutralizing potential Occurrence offered pandemic participant Participants Patient Post-infection progression quantification quantification immune response. Rapid SARS-CoV-2 SARS-CoV-2 antibody serological serological test specific antigen Support Symptom symptomatic vaccination Vaccine WHO
[DOI] 10.3389/fimmu.2022.915338 PMC 바로가기

Gene Network Analysis of the Transcriptome Impact of SARS-CoV-2 Interacting MicroRNAs in COVID-19 Disease

COVID-19 질병에서 SARS-CoV-2 상호작용 MicroRNA의 전사체 영향에 대한 유전자 네트워크 분석

Review

Published on 2022-08-172022-09-11
Journal: International Journal of Molecular Sciences [Category] SARS, 유전자 메커니즘,

[키워드] affected Analysis biochemical biological processes Cell cell cycle cell surface receptor changes characterized COVID-19 COVID-19 disease cytokine death DEGs differentially expressed differentially expressed gene Differentially expressed genes downregulated exploratory FIVE functional enrichment Functional enrichment analysis Gene Expression gene network Health Organization heart Impact involved kidneys list lung Lymph node microRNA MicroRNAs mitochondrial mitotic mitotic cell modulation molecular Multiorgan multiorgan disease network network analysis pathological mechanism Pathways Perspective predicted provide reported SARS-CoV-2 SARS-CoV-2 virus signaling pathway submitted surface receptor target tissue tissues transcriptomes translated upregulated WHO with COVID-19 World Health Organization
[DOI] 10.3390/ijms23169239 PMC 바로가기 [Article Type] Review

Evaluation of Impact of a Pharmacist-Led Educational Campaign on Disease Knowledge, Practices and Medication Adherence for Type-2 Diabetic Patients: A Prospective Pre- and Post-Analysis

Randomized Controlled Trial

Published on 2022-08-152022-10-05
Journal: International Journal of Environmental Research an [Category] 임상,

The COVID-19 Pandemic: Reshaping Public Health Policy Response Envisioning Health as a Common Good

COVID-19 팬데믹: 공동선으로서의 건강을 구상하는 공중 보건 정책 대응 재편

Editorial

Published on 2022-08-122022-09-11
Journal: International Journal of Environmental Research an [Category] SARS, 치료기술,

[키워드] China Cluster common COVID-19 Good Health Organization Pneumonia Policy Public response unknown cause WHO World Health Organization Wuhan
[DOI] 10.3390/ijerph19169985 PMC 바로가기 [Article Type] Editorial

How concerning is a SARS-CoV-2 variant of concern? Computational predictions and the variants labeling system

Article

Published on 2022-08-102022-11-16
Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 변종,

2-deoxy-D-glucose as an adjunct to standard of care in the medical management of COVID-19: a proof-of-concept and dose-ranging randomised phase II clinical trial

Clinical Trial

Published on 2022-08-042022-10-04
Journal: BMC Infectious Diseases [Category] SARS, 임상,

[키워드] 2-deoxy-D-glucose 2-DG acute COVID-19 addition Administered adverse event age analyzed approach clinical benefit clinical recovery clinical study clinical trial conducted COVID-19 CTRI discharge dose efficacious therapeutic Efficacy Efficacy and safety evaluate evaluated hazard In-vitro intensive care Isolation limit management median metabolic inhibitor Mild moderate Mortality Negative conversion Normalisation Open-label outcomes Patient progression randomised randomised clinical trial Randomized receive reported RT-PCR SARS-CoV-2 severe COVID-19 severe COVID-19 patients shown significantly shorter standard care Standard of care time Tolerability treated Treatment Trial vital sign WHO
[DOI] 10.1186/s12879-022-07642-6 PMC 바로가기 [Article Type] Clinical Trial

Allosteric Binding Sites of the SARS-CoV-2 Main Protease: Potential Targets for Broad-Spectrum Anti-Coronavirus Agents

SARS-CoV-2 주요 프로테아제의 알로스테릭 결합 부위: 광범위한 항 코로나바이러스 제제의 잠재적 표적

Review

Published on 2022-08-022022-09-11
Journal: Drug design, development and therapy [Category] SARS, 치료제,

Soluble CD137 as a potential biomarker for severe COVID-19

Article

Published on 2022-08-012022-10-05
Journal: Immunology letters [Category] 바이오마커,

[키워드] 24 hour acute respiratory syndrome Analysis Biomarker Blood Brazil Care caused CD137 characterized Clinical outcome contagious Control coronavirus Coronavirus disease 2019 correlation COVID-19 critical COVID-19 patient Critically ill patient cytokine Cytokines demonstrated disease disease severity evaluate evaluated growth factor Growth factors Health healthy blood donors high risk highly pathogenic hospital ICU ICU admission identify immune increase in increased risk Infection intensive care isoform mechanical ventilation membrane-bound mortality rate Necrosis outcomes pandemic Potential biomarker potential therapy primary endpoint Prospective Study receptor recruitment regulate responsible SARS-CoV-2 severe COVID-19 severe SARS-CoV-2 severity Soluble CD137 Soluble immune checkpoints T-cell activation therapeutic targets TNF was related was used WHO with COVID-19 World Health Organization
[DOI] 10.1016/j.imlet.2022.07.003 [Article Type] Article

Monkeypox: another test for PCR

원숭이두(Monkeypox): PCR에 대한 또 다른 테스트

Article

Published on 2022-08-012022-09-11
Journal: Eurosurveillance [Category] Fulltext, 원숭이두창, 유전자 메커니즘, 치료기술,