Innate immune evasion by SARS-CoV-2: Comparison with SARS-CoVReview Published on 2020-11-012023-07-12 Journal: Reviews in Medical Virology [Category] SARS, [키워드] Coronaviruses IFN-α/β immune evasion Innate immunity NLRP3 inflammasome SARS-CoV-2 [DOI] 10.1002/rmv.2135 [Article Type] Review
Aminoglycosides can be a better choice over macrolides in COVID-19 regimen: Plausible mechanism for repurposing strategy아미노글리코사이드는 COVID-19 요법에서 마크로라이드보다 더 나은 선택이 될 수 있습니다: 용도 변경 전략을 위한 그럴듯한 메커니즘Article Published on 2020-11-012022-08-31 Journal: Medical Hypotheses [Category] SARS, 변종, 신약개발, 유전자 메커니즘, 치료제, [키워드] Aminoglycoside Andrographis antiviral activity Azithromycin clarithromycin COVID-19 COVID-19 pandemic defensin Defensins ENhance enhancer Immunity Innate Innate immunity lack mechanism microbes regimen reported repurposing Repurposing strategy. respiratory respiratory infection respiratory infections [DOI] 10.1016/j.mehy.2020.109984 PMC 바로가기 [Article Type] Article
Hydrogen peroxide and viral infections: A literature review with research hypothesis definition in relation to the current covid-19 pandemicReview Published on 2020-11-012023-07-12 Journal: Med Hypotheses [Category] SARS, [키워드] coronavirus COVID-19 hydrogen peroxide Innate immunity SARS-CoV-2 viruses [DOI] 10.1016/j.mehy.2020.109910 PMC 바로가기 [Article Type] Review
Role of latent tuberculosis infections in reduced COVID-19 mortality: Evidence from an instrumental variable method analysisArticle Published on 2020-11-012023-07-12 Journal: Med Hypotheses [Category] SARS, [키워드] BCG COVID-19 Innate immunity Instrumental variable method latent tuberculosis infection trained immunity [DOI] 10.1016/j.mehy.2020.110214 PMC 바로가기
Hypoxia: A key feature of COVID-19 launching activation of HIF-1 and cytokine stormReview Published on 2020-10-292022-10-29 Journal: Journal of Inflammation (London, England) [Category] COVID-19, [키워드] activated Activation acute lung injury acute respiratory distress Angiogenesis ARDS caused cell proliferation cellular processe COVID-19 COVID-19 pathogenesis Cytokine storm disease Factor HIF-1 HIF-1α HIF-1α hypoxia immune cells immune response Impact Inflammation Inflammatory response inflammatory site Innate immunity innate immunity cells lung metabolism moderate New coronavirus patient’s death Pneumonia pro-inflammatory cytokine regulate respiratory virus SARS-CoV-2 severe cases Spread Symptom syndrome [DOI] 10.1186/s12950-020-00263-3 PMC 바로가기 [Article Type] Review
Tea Bioactive Modulate Innate Immunity: In Perception to COVID-19 Pandemic차 생체 활성 조절 타고난 면역: COVID-19 전염병에 대한 인식Review Published on 2020-10-282022-08-31 Journal: Frontiers in Immunology [Category] MERS, SARS, 치료제, [키워드] accumulate activate affected animal model animal models anti-inflammatory properties caffeine Camellia sinensis cascade combating condition copper coronavirus coronavirus disease COVID 19 COVID-19 COVID-19 pandemic Cytokines Disease progression Disruption Drawing effective EGCG ENhance epigallocatechin epigallocatechin gallate experiments gallate green Immunity immunomodulatory impairment In-vitro Infectious disease Infectious diseases Innate innate immune response Innate immunity interferons iron manganese medium Micronutrient micronutrients mitigate modulate natural killer cell Natural killer cells Novel coronavirus novel coronavirus disease nutritional immunity oxygen Pathways Perception pro-inflammatory cytokines processed provide reactive oxygen specy Selenium signaling pathway Soil tea tea polyphenols theaflavin theobromine theophylline trials upregulating Vitamin vitamins water Zinc [DOI] 10.3389/fimmu.2020.590716 PMC 바로가기 [Article Type] Review
Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analysesArticle Published on 2020-10-272022-10-04 Journal: Scientific Reports [Category] MERS, 유전자 메커니즘, 임상, [키워드] Analysis association Bacillus BCG BCG vaccination benefit boost clinical trial co-morbidities confounding variables correlation country COVD-19 COVID-19 COVID-19 outbreak death rate Diseases epidemiological epidemiological finding Evidence Health policy incidence of COVID-19 infection with SARS-CoV-2 initial Innate immunity Mortality Numerous Prevalence Prevent protection provide reduced Registered Respiratory tract diseases SARS-CoV-2 severity of COVID-19 significantly smoking Spread supported thought Tuberculosis Vaccine variable while [DOI] 10.1038/s41598-020-75491-x PMC 바로가기 [Article Type] Article
SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral responseArticle Published on 2020-10-272022-11-01 Journal: Cellular and Molecular Immunology [Category] COVID-19, MERS, SARS, [키워드] aggregation antiviral response cause downstream evade glycoprotein host immunity immune evasion innate immune response Innate immunity Interaction IRF3 M protein MAVS mechanism membrane Membrane glycoprotein M morbidity Mortality pathogen Pathways Protein recruitment SARS-CoV-2 SARS-related coronavirus TBK1 TRAF3 type I interferon [DOI] 10.1038/s41423-020-00571-x PMC 바로가기 [Article Type] Article
Title: Cytokine release syndrome is not usually caused by secondary hemophagocytic lymphohistiocytosis in a cohort of 19 critically ill COVID-19 patientsArticle Published on 2020-10-262022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 임상, [키워드] absence Admission Analysis appear approach ARDS assessment caused Clinical course Cohort Course courses COVID-19 COVID-19 patient criteria Critically ill CRS Cytokine release syndrome Cytokines death declining Diagnostic Criteria discharge dominant feature Fever HLH hyperinflammation Hyperinflammatory ICU immunology immunosuppressive implication IMPROVE independent Infection Inflammation Innate immune cells Innate immunity macrophage activation syndrome median neutrophil neutrophilic observation period outcomes over Patient reached Respiratory failure secondary hemophagocytic lymphohistiocytosis severe disease sHLH subgroups of patient syndrome tested therapy Trajectories Treatment virus were assessed [DOI] 10.1038/s41598-020-75260-w PMC 바로가기 [Article Type] Article
Numbers Game and Immune Geography as Determinants of Coronavirus PathogenicityCellular and Infection Microbiology Published on 2020-10-232022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] Coronavirus, MERS, [키워드] COVID-19 determinant game Geography IFN-I Innate immunity number Pathogenesis SARS - CoV-2 viral dynamics [DOI] 10.3389/fcimb.2020.559209 PMC 바로가기 [Article Type] Cellular and Infection Microbiology