Global dynamic analysis of a H7N9 avian-human influenza model in an outbreak regionArticle Published on 2015-02-212023-06-02 Journal: Journal of theoretical biology [Category] 조류인플루엔자, [키워드] Equilibria Mutant avian influenza virus persistence Simulation stability [DOI] 10.1016/j.jtbi.2014.12.002
Livestock-associated MRSA: innocent or serious health threat?Editorial Published on 2015-01-012023-06-02 Journal: Future Microbiology [Category] 조류인플루엔자, [키워드] Infection livestock-associated MRSA persistence Transmission [DOI] 10.2217/fmb.15.1 [Article Type] Editorial
Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolatesResearch Article Published on 2014-12-222022-10-28 Journal: BMC Genomics [Category] Coronavirus, [키워드] Activation acute respiratory syndrome Amino acid Analysis analyzed approach Atypical Calu-3 caused Cell cell line changes changes in clinical Clustering Computational topology coronavirus Cytokine simulation differential expression epithelial Extracellular feature filtered Gene Expression highly pathogenic homology host response human airway epithelial human Calu-3 humans IFN IL-1α in viral include Infection innate immune Innate immunity isolate kinetic magnitude MERS MERS-CoV MERS-CoV infection Middle East modulate Novel coronavirus pathogenic patients performed persistence Pneumonia post infection pro-inflammatory pro-inflammatory responses progressive respiratory failure Protein respiratory virus responses Result SARS-CoV Signaling STAT3 statistical analysis strain Strains supplementary material syndrome TNF transcriptional transcriptional change transcriptional difference transcriptomics zoonotic [DOI] 10.1186/1471-2164-15-1161 PMC 바로가기 [Article Type] Research Article
Global and Local Persistence of Influenza A(H5N1) VirusArticle Published on 2014-08-012023-05-31 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] Avian Influenza H5N1 Influenza migration network persistence Source viruses [DOI] 10.3201/eid2008.130910 PMC 바로가기
Requirements for Pseudomonas aeruginosa Acute Burn and Chronic Surgical Wound Infection녹농균 급성 화상 및 만성 외과적 상처 감염에 대한 요건Research Article Published on 2014-07-242022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major accompanied acute and chronic infections acute and chronic P. aeruginosa wound infections acute and non-diabetic chronic wound infections acute burn wound infections acute infection acute infections acute wounds addition amino acids Bacterial bed sores Burn burn wound burn wound infections burns carbon carbon source caused chemotactic chemotaxis chronic chronic and acute wounds chronic infection chronic infections chronic wound chronic wound infections cofactor cofactors colonization complex Critical determinant diabetic ulcers energy expression Fatty acid fatty acids fitness flagellar function Gene Expression Gene expression profiling Genetic genomic growth healthcare high mortality High-throughput sequencing in vivo Infection infections insertion Intensive Intervention metabolic genes murine model murine models mutant non-diabetic chronic wound infection non-diabetic chronic wound infections not correlated nutritional requirements opportunistic infection opportunistic Infections opportunistic pathogen P. aeruginosa P. aeruginosa wound infections pathogen Pathogenesis persistence power primary source profiles Pseudomonas aeruginosa purines Requirement RNA-Seq Sepsis Sequencing Soft tissue Soft tissue infections Spread Strains Surgical Wound Infection These data tissue damage Tn-seq trajectory Transcriptome Travel utility Variation virulence while Wound Infection wound infections [DOI] 10.1371/journal.pgen.1004518 PMC 바로가기 [Article Type] Research Article
Immune memory to hepatitis B persists in children aged 7–8 years, who were vaccinated in infancy with 4 doses of hexavalent DTPa-HBV-IPV/Hib (Infanrix™ hexa) vaccineB형 간염에 대한 면역 기억은 유아기에 6가 DTPa-HBV-IPV/Hib(Infanrix™ 헥사) 백신 4회 접종을 받은 7~8세 어린이에게서 지속됩니다.journal-article Published on 2014-06-042024-07-30 Journal: Human vaccines & immunotherapeutics [Category] 백일해, 파상풍, [키워드] Anti-HBs hepatitis B immune memory long-term persistence [DOI] 10.4161/hv.28480 [Article Type] journal-article
Genotypic and Functional Impact of HIV-1 Adaptation to Its Host Population during the North American Epidemic북미 전염병 동안 숙주 인구에 대한 HIV-1 적응의 유전형 및 기능적 영향Research Article Published on 2014-04-242022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accumulate adaptation analyzed Antiviral antiviral immunity assessment average Boston cellular immunity changes in characterized circulating codon Cohort Consensus consequence detectable enrolled Epidemic ERAS escape mutation Evolution exhibiting explain Frequency functional Gag greater HIV HIV-1 HLA Host immune immune escape mutation immune escape mutations Impact implication in vitro Increases individual information median medians Mutation New York North North America Patient persistence phenotypic Phylogeny polymorphism Polymorphisms Population Protective Protein reconstructed reduce remained replication capacity residue Result San Francisco selected sequence specimen Spread subsequent suggested Support the epidemic the median Transmission unlikely Viral viral fitness Viral proteins virus [DOI] 10.1371/journal.pgen.1004295 PMC 바로가기 [Article Type] Research Article
Residence ofStreptococcus pneumoniaeandMoraxella catarrhaliswithin polymicrobial biofilm promotes antibiotic resistance and bacterial persistencein vivo다종균 생물 막 내에서 폐렴 연쇄구균과 콧물 모라크셀라의 생존은 항생제 저항성과 세균의 지속성을 촉진한다.journal-article Published on 2014-04-012024-08-04 Journal: Pathogens and Disease [Category] 폐렴구균 감염증, [키워드] antibiotic biofilm otitis persistence [DOI] 10.1111/2049-632X.12129 [Article Type] journal-article
Porcine epidemic diarrhea virus (PEDV) co-infection induced chlamydial persistence/stress does not require viral replicationMicrobiology Published on 2014-01-092022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] Coronavirus, MERS, [키워드] Chlamydia pecorum absence Alter aminopeptidase N binding CD13 Cell cellular signaling pathway characteristic Chlamydia Chlamydiae chlamydial persistence chlamydial stress response chronic inflammation Co-infection contribute Course Critical Culture cycloheximide de novo demonstrated developmental disease drug epidemic diarrhea experiment Host host cell receptor incubated indicated induce Infected Infection infectious inhibit inhibited non-infectious PEDV performed persistence Porcine epidemic diarrhea virus produced protein synthesis reduced removed Replication replicative required stimulate stressed chlamydiae Vero Cell Viral protein viral replication virus [DOI] 10.3389/fcimb.2014.00020 PMC 바로가기 [Article Type] Microbiology
A Leaderless Genome Identified during Persistent Bovine Coronavirus Infection Is Associated with Attenuation of Gene ExpressionResearch Article Published on 2013-12-122022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] addition Analysis attenuation Bovine coronavirus Cell culture contribute determined different downstream Efficiency example expression found Frame Genome genomes genomic genomic RNA Identified Infected Infection mutant viruses ORF persistence persistent Postinfection replicative retained RNA selected sequence sgmRNA subgenomic mRNA Transcription translation viral infection was impaired [DOI] 10.1371/journal.pone.0082176 PMC 바로가기 [Article Type] Research Article