Emergency Use Authorization for Remdesivir and Its Potential Implications렘데시비르의 긴급 사용 승인 및 잠재적 영향Article Published on 2021-03-012022-09-11 Journal: Therapeutic innovation & regulatory science [Category] SARS, 치료제, [키워드] authorization Emergency Potential [DOI] 10.1007/s43441-020-00212-5 PMC 바로가기 [Article Type] Article
Remdesivir: Critical Clinical Appraisal for COVID 19 Treatment렘데시비르: COVID 19 치료에 대한 중요한 임상 평가Review Published on 2021-03-012022-09-11 Journal: Drug research [Category] SARS, 신약개발, 유전자 메커니즘, 임상, 치료제, [키워드] appraisal approved authorization clinical Clinical research Clinical studies clinical trial conducted COVID 19 COVID19 effective Emergency Hope In-vitro information mechanism MERS molecule Regulatory Remdesivir Research therapeutic molecules Usage virus [DOI] 10.1055/a-1288-4078 PMC 바로가기 [Article Type] Review
Pride and Prejudice during the COVID-19 Pandemic: The Misfortune of Inappropriate Clinical Trial DesignCOVID-19 전염병 동안의 오만과 편견: 부적절한 임상 시험 설계의 불행Article Published on 2021-03-012022-09-11 Journal: Journal of Epidemiology and Global Health [Category] SARS, 임상, [키워드] anticipated antivirals classic clinical Clinical outcome clinical trial clinical trials collaboration complications conducted controlled trials coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Effectiveness Emergency evaluate example global pandemic Health Organization Intervention management MOST multi-center non-randomized studies non-randomized study pandemic Placebo Placebo effect practicality precedence Pride and Prejudice primary endpoint randomization Randomized controlled trials randomized trials Registered Research protocol secure several limitation several limitations Simultaneous single-arm single-arm. single-center therapeutic Treatment Trial World Health Organization [DOI] 10.2991/jegh.k.200729.001 PMC 바로가기 [Article Type] Article
Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort studySARS-CoV2에 감염된 환자의 혈청에서 키누레닌 대 트립토판 비율 증가: 관찰 코호트 연구Observational Study Published on 2021-03-012022-09-11 Journal: Biochimica et biophysica acta. Molecular basis of [Category] MERS, SARS, 바이오마커, 임상, [키워드] activated Activation acute respiratory distress acute respiratory distress syndrome addition age balance Biomarker Cytokines death dysregulation Emergency emergency room examined hallmark healthy controls healthy subject healthy subjects highest HPLC immune immune dysregulation immune reactivity immune tolerance increase in Increased Infection Inflammation inflammatory state intensive care intensive care unit Italy Kynurenine Kynurenine pathway Kynurenine:Tryptophan ratio lymphopenia males mechanism metabolism Observational cohort study Patient patients positive patients positively correlated pro-inflammatory cytokine pro-inflammatory cytokines reactivity recruited reflect respiratory distress Respiratory distress syndrome Rome room SARS-CoV2 SARS-CoV2 infection serum Serum level severe lymphopenia severity Severity of infection Severity of infection. significant difference Stage syndrome therapeutic intervention Tolerance Tryptophan were assessed [DOI] 10.1016/j.bbadis.2020.166042 PMC 바로가기 [Article Type] Observational Study
[Clinical and epidemiological characteristics of SARS-CoV-2 infections in family physicians: A case-control study]Observational Study Published on 2021-03-012022-10-04 Journal: Atencion Primaria [Category] 임상, [키워드] Care Case-control case-control study Characteristics Comorbidity Comorbilidad Contact Control Coronavirus infections cough COVID-19 COVID-19 disease COVID-19 patient Del Diagnosis Emergency English epidemiological Evaluación de síntoma facilitate family Family physicians fatigue Fever headache hospital identify infected with SARS-CoV-2 Infection Logistic regression manifested Médicos de familia participated Pathologies PCR PCR positive physician primer RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus infection Sociodemographic Spanish Symptom Symptom assessment the SARS-CoV-2 the SARS-CoV-2 virus these symptom tiredness variable virus [DOI] 10.1016/j.aprim.2020.12.001 PMC 바로가기 [Article Type] Observational Study
ENT emergencies during the first wave of COVID-19 pandemic in Spain: Our experienceObservational Study Published on 2021-03-012022-10-05 Journal: American journal of otolaryngology [Category] 임상, [키워드] ambulatory Ambulatory care carried Characteristics confirmed case correlated correlation COVID-19 COVID-19 pandemic Critical decrease Department Emergency emergency medicine epidemiological situation explain First wave Generalized linear model Health health system Hospital administration Neck not affect otolaryngology predominant Primary Health Care reduction in remained Retrospective study SARS-CoV-2 SARS-CoV-2 pandemic Spanish surgery the SARS-CoV-2 university hospital [DOI] 10.1016/j.amjoto.2020.102865 PMC 바로가기 [Article Type] Observational Study
An algorithm in ophthalmic emergencies to evaluate the necessity of physical consultation during COVID-19 lockdown in Paris: Experience of the first 100 patientsObservational Study Published on 2021-03-012022-10-05 Journal: Journal français d'ophtalmologie [Category] 임상, [키워드] Algorithm approach clinically confinement COVID-19 defined Diagnosis Distanciation sociale Emergency Emergency ophthalmology English evaluate experience Final French help identify lockdown management Negative predictive value Observational cohort study one patient Ophtalmologie d’urgence ophthalmic past medical history Patient patients physical positive Positive predictive value questionnaire Questionnaires recommendation reduction reliability retrospective sensitivity severity social distancing specificity suggested Symptom telemedicine visits Téléophtalmologie. teleophthalmology [DOI] 10.1016/j.jfo.2020.12.002 PMC 바로가기 [Article Type] Observational Study
Urgent/emergency surgery during COVID-19 state of emergency in Portugal: a retrospective and observational studyObservational Study Published on 2021-03-012022-10-05 Journal: Brazilian journal of anesthesiology (Elsevier) [Category] 임상, [키워드] 2020 COVID-19 pandemic Admission affected analysed Care changed Characteristics conducted correlated country COVID-19 COVID-19 case COVID-19 diagnostic testing COVID-19 pandemic COVID-19 patients Department diagnostic Efficiency Emergency emergency service Emergency service, hospital Evolution examined good quality growth health care facility homologous hospital less medical record Mortality mortality rate National no difference number of infected operative pandemic Patient Population Portugal preoperative reduce reduction in reported retrospective SARS-CoV-2 virus screening strategy surgical Surgical procedures, operative. Volume [DOI] 10.1016/j.bjane.2021.01.003 PMC 바로가기 [Article Type] Observational Study
Timing and volume of information produced for the Otolaryngologist during the COVID-19 pandemic in the UK: A review of the volume of online literatureArticle Published on 2021-03-012023-07-13 Journal: Clinical otolaryngology : official journal of ENT- [Category] SARS, [키워드] aerosol-generating procedures Elective Emergency ENT head and neck cancer healthcare SARS-CoV-2 service [DOI] 10.1111/coa.13669 PMC 바로가기
COVID-19 Presenting as Encephalopathy in the Emergency Department: A Case ReportCase Report Published on 2021-02-262022-10-31 Journal: Clinical Practice and Cases in Emergency Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Altered mental status Anosmia Case report Central nervous system clinically Community conscious coronavirus disease Coronavirus-2 COVID-19 COVID-19 infection death described Emergency Encephalopathy etiology Evidence Fever headache Healthcare provider highlight increasingly infection control male Measures Meningitis neuropathic novel SARS-CoV-2 virus pandemic pathogenesis of COVID-19 Patient presenting report Respiratory system SARS-CoV-2 Symptom [DOI] 10.5811/cpcem.2020.12.50036 PMC 바로가기 [Article Type] Case Report