eight – Page 73 – Communicable Diseases Research

Direct hemoperfusion using a polymyxin B-immobilized polystyrene column for COVID-19

COVID-19에 대해 폴리믹신 B 고정 폴리스티렌 컬럼을 사용한 직접 혈액 관류

Observational Study

Published on 2021-06-012022-09-11
Journal: Journal of clinical apheresis [Category] 바이오마커, 임상,

Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in healthy adults aged 60 years and older: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial

60세 이상의 건강한 성인을 대상으로 한 불활성화 SARS-CoV-2 백신(CoronaVac)의 안전성, 내약성 및 면역원성: 무작위, 이중 맹검, 위약 대조, 1/2상 임상 시험

Randomized Controlled Trial

Published on 2021-06-012022-09-11
Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 임상, 진단, 치료기술,

[키워드] Adults Adverse reaction Adverse reactions age All participants Aluminium aluminium hydroxide antibody Antibody Response Antibody titre assigned baseline Beijing block Block randomisation China Chinese clinical trial CoronaVac COVID-19 COVID-19 vaccine Cutoff defined detectable development dose dose-escalation double-blind eight Endpoint enrolled groups healthy hydroxide immunogenicity inactivated injection injection site pain intervention group Intramuscular injection investigators Laboratory live SARS-CoV-2 Mild moderate morbidity morbidity and mortality Neutralising Antibodies neutralising antibody neutralising antibody titres occurred Older Older adults participant Participants Phase 1 Phase 2 phase 3 trial Placebo placebo group placebo-controlled positive primary immunogenicity Program random assignment randomised Randomly receive Registered reported research and development Safe Safety safety population SARS-CoV-2 SARS-CoV-2 vaccine Science second dose Serious Adverse Events Seroconversion seroconversion rate seronegative seropositive Seven severity technology the disease the placebo group titre Tolerability treatment allocation trial protocol vaccination Vaccine virus
[DOI] 10.1016/S1473-3099(20)30987-7 PMC 바로가기 [Article Type] Randomized Controlled Trial

Four Weeks of Detraining Induced by COVID-19 Reverse Cardiac Improvements from Eight Weeks of Fitness-Dance Training in Older Adults with Mild Cognitive Impairment

Article

Published on 2021-05-312022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS,

[키워드] Acute respiratory infection Adults aerobic age aging Analysis average baseline levels benefit bpm cardiac Cardiovascular health change Cognitive impairment combined training COVID-19 Dance effective eight females fitness generate Health heart rate HRV improvement induced Intervention lockdown lockdowns maintain male measure mental health Mild MONITOR Older one-way ANOVA pandemic Pandemics parameter participant participated performance physical physical activity Pro promote reduced reducing response responsiveness reversed severity strength Symptom team training training cessation Variability was used Week were used wireless zone
[DOI] 10.3390/ijerph18115930 PMC 바로가기 [Article Type] Article

Serial markers of coagulation and inflammation and the occurrence of clinical pulmonary thromboembolism in mechanically ventilated patients with SARS-CoV-2 infection; the prospective Maastricht intensive care COVID cohort

Research

Published on 2021-05-312022-10-29
Journal: Thrombosis Journal [Category] COVID-19,

[키워드] addition adjusted age analysed Anticoagulants average Biomarker body mass index C-reactive protein cardiac thrombus clinical Coagulation Cohort Computed tomography Concentration COVID COVID-19 CRP CTPA D-dimer eight excluded ferritin fibrinogen hypothesise incidence Inflammation intensive care Linear regression model Lower marker mechanically ventilated patient Occurrence on mechanical ventilation outcome Patient positive Prospective Study Protein pulmonary angiography Pulmonary embolism pulmonary thrombosis Result risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient sensitivity analysis Sex significantly statistical significance supplementary material therapy Thromboembolism thrombus formation tissue plasminogen activator vessels were measured
[DOI] 10.1186/s12959-021-00286-7 PMC 바로가기 [Article Type] Research

Engagement and Effectiveness of a Healthy-Coping Intervention via Chatbot for University Students During the COVID-19 Pandemic: Mixed Methods Proof-of-Concept Study

Original Paper

Published on 2021-05-282022-10-31
Journal: JMIR mHealth and uHealth [Category] Coronavirus, SARS,

[키워드] age Analysis Anxiety anxiety symptom asked attrition average baseline benefit chatbot chatbots cognitive collected Complete COVID-19 COVID-19 pandemic Critical decrease Depression Digital Digital health distress Effectiveness eight Engagement extreme female form GAD-7 Generalized healthy healthy-coping intervention improvement increasingly Intervention mental health mental health problems mental health services mindfulness mobile mental health objective offer participant Perceived Stress Scale Positive psychology postintervention provided PSS-10 psychoeducational psychological support questionnaire recruited required Research Result seeking significant decrease significantly Stress stress symptom student study period subscale scores Support therapy university university student university students user while
[DOI] 10.2196/27965 PMC 바로가기 [Article Type] Original Paper

The Soundscape of the COVID-19 Lockdown: Barcelona Noise Monitoring Network Case Study †

Article

Published on 2021-05-282022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS,

[키워드] L_Aeq Analysis annoyance Barcelona caused comparison conducted COVID-19 decrease drastic eight lockdown measure moderate monitoring network noise level reduction significant decrease soundscape Spain Stage WASN
[DOI] 10.3390/ijerph18115799 PMC 바로가기 [Article Type] Article

Spike in Rhino-Orbital-Cerebral Mucormycosis Cases Presenting to a Tertiary Care Center During the COVID-19 Pandemic

Medicine

Published on 2021-05-282022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

Liver and Kidney Function Biomarkers, Blood Cell Traits and Risk of Severe COVID-19: A Mendelian Randomization Study

Genetics

Published on 2021-05-272022-10-31
Journal: Frontiers in Genetics [Category] COVID-19,

An optimized transfer learning-based approach for automatic diagnosis of COVID-19 from chest x-ray images

Bioinformatics

Published on 2021-05-272022-10-29
Journal: PeerJ Computer Science [Category] COVID-19,

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans

Research

Published on 2021-05-272022-10-05
Journal: Nature [Category] SARS, 변종, 유전자 메커니즘, 임상, 치료제,

[키워드] adaptive antibody BNT162b2 BNT162b2 vaccine boost CD4+ CD8+ CD8+ T cell cells Cellular immune response circulating conserved COVID-19 demonstrated detectable doses Efficacy eight elicit elicited ENCODE epitope geometric healthy Human humoral immune response individual induce Lipid nanoparticle MHC allele MOST Mutant strains neutralized Neutralizing neutralizing antibody nine nucleoside-modified mRNA observation period participant phenotype prefusion conformation presenting pseudovirus SARS-CoV-2 SARS-CoV-2 variants serum spike glycoprotein T cell T helper the SARS-CoV-2 titre Trial vaccination variants
[DOI] 10.1038/s41586-021-03653-6 [Article Type] Research