Serological identification of SARS-CoV-2 infections among children visiting a hospital during the initial Seattle outbreakArticle Published on 2020-09-012022-10-29 Journal: Nature Communications [Category] COVID-19, SARS, [키워드] Adults Care children collected COVID-19 COVID-19 case COVID-19 disease disease Epidemiology Frequency hospital identify infected children initial less MOST neutralized Neutralizing activity outbreak Paediatric research pediatric positive SARS-CoV-2 SARS-COV-2 infection Seattle Seattle Children’s Hospital seeking sera Serologically seropositive Seven The United States viral infection were infected [DOI] 10.1038/s41467-020-18178-1 PMC 바로가기 [Article Type] Article
Human post‐infection serological response to the spike and nucleocapsid proteins of SARS‐CoV‐2Short Article Published on 2020-08-252022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] COVID-19, [키워드] antibodies average characterized collected comparable COVID‐19 COVID‐19 patient Epidemiology Frequency Human individuals nucleocapsid nucleocapsid protein response SARS‐CoV‐2 SARS‐CoV‐2 sera serological response serology specificity spike tested Viral proteins [DOI] 10.1111/irv.12798 PMC 바로가기 [Article Type] Short Article
A highly specific and sensitive serological assay detects SARS-CoV-2 antibody levels in COVID-19 patients that correlate with neutralization매우 특이적이고 민감한 혈청학적 분석은 중화와 상관관계가 있는 COVID-19 환자의 SARS-CoV-2 항체 수준을 감지합니다Original Paper Published on 2020-08-212022-09-10 Journal: Infection [Category] MERS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition anti-SARS-CoV-2 antibody antibodies antibody Antibody test antigens Assay validation controls coronavirus correlated correlation COVID-19 COVID-19 patient cross-react described detect develop domain ectodomain ELISA enzyme IgA IgG immunosorbent Infection infection rate infection rates infections monitoring national health system neutralization objective pandemic parameter Patient protective immunity protocol public health measure public health measures R 2 RBD RBD ELISA RBD-based ELISA Receptor binding domain respiratory response Result robust S protein SARS-CoV-2 SARS-CoV-2 antibody seasonal coronaviruses sensitivity sera Seroconversion Serological assay serology Seroprevalence serum severe acute respiratory syndrome Coronavirus specificity Spike protein supplementary material symptom onset the RBD threshold thresholds vaccination Virus neutralization were measured [DOI] 10.1007/s15010-020-01503-7 PMC 바로가기 [Article Type] Original Paper
Low risk of serological cross-reactivity between dengue and COVID-19Short Communication Published on 2020-08-142022-10-29 Journal: Memórias do Instituto Oswaldo Cruz [Category] COVID-19, MERS, SARS, [키워드] Accuracy antibodies Coronavirus disease 2019 COVID-19 COVID-19 antibody cross-reactivity Dengue dengue patients diagnostic Epidemics false-positive result health system investigated overlap positive Rapid test regions risk SARS-CoV-2 sera serological serological cross-reaction tested tropical virus [DOI] 10.1590/0074-02760200225 PMC 바로가기 [Article Type] Short Communication
A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluationArticle Published on 2020-08-132022-10-04 Journal: Nature Communications [Category] MERS, 치료기술, 치료법, [키워드] antibody Antibody titer approach Bacterial comparable Convalescent plasma therapy COVID-19 COVID-19 diagnosis COVID-19 patient cross detect determine develop Efficacy gold standard infections Infectious-disease diagnostics Local neutralization Neutralization assay Neutralizing neutralizing antibody Neutralizing antibody titer offer parameter Patient platform public health reduction SARS-CoV-2 SARS-CoV-2 neutralization SARS-CoV-2 neutralizing antibody scaled sera Serological testing specimen Vaccine Vaccine development [DOI] 10.1038/s41467-020-17892-0 PMC 바로가기 [Article Type] Article
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults Research Published on 2020-08-122022-10-05 Journal: Nature [Category] 유전자 메커니즘, 임상, [키워드] accumulating acute respiratory syndrome Administered age BNT162b1 caused Concentration convalescent coronavirus coronavirus disease COVID-19 death domain dose dose-dependent dose-escalation ENCODE event generally mild geometric mean healthy human sera immunogenicity data Increased immunogenicity lack local reaction moderate mRNA vaccine Neutralizing nucleoside-modified mRNA observer-blinded pandemic placebo-controlled positive SARS-CoV-2 PCR Randomized RBD RBD-binding IgG reached reactogenicity receive reported RNA vaccine SARS-CoV-2 second dose second vaccination sera single dose spike glycoprotein Support titre Tolerability Vaccine WHO World Health Organization [DOI] 10.1038/s41586-020-2639-4 [Article Type] Research
Repeated leftover serosurvey of SARS-CoV-2 IgG antibodies, Greece, March and April 2020Rapid Communication Published on 2020-08-062022-10-31 Journal: Eurosurveillance [Category] COVID-19, Fulltext, MERS, [키워드] COVID-19 COVID-19 incidence Effectiveness Fatality rate females Greece IgG antibody individual Infection Measures Older positive Prevalence Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 IgG antibodies sera Seroprevalence Serosurvey was performed [DOI] 10.2807/1560-7917.ES.2020.25.31.2001369 PMC 바로가기 [Article Type] Rapid Communication
Comparison of diagnostic accuracies of rapid serological tests and ELISA to molecular diagnostics in patients with suspected coronavirus disease 2019 presenting to the hospitalComparative Study Published on 2020-08-012022-10-06 Journal: Clinical microbiology and infection : the official [Category] SARS, 진단, [키워드] 95% CI Accuracy acute respiratory syndrome Analysis C-reactive protein (CRP Characteristics Cohort coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRP diagnostic diagnostics disease eligible ELISA evaluated heterogeneous hospital immunochromatographic assay individual Lateral lateral flow lateral flow immunoassay molecular NAT NATs nucleic acid amplification Orient Patient patient control group patients plasma sample presenting Rapid rapid serological test Rapid test respiratory sample respiratory symptom SARS-CoV-2 sensitivity sera serology severe acute respiratory syndrome coronavirus 2 specificity Symptom Symptoms Test Variability [DOI] 10.1016/j.cmi.2020.05.028 PMC 바로가기 [Article Type] Comparative Study
Point-of-Care Diagnostics of COVID-19: From Current Work to Future PerspectivesReview Published on 2020-07-312022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, SARS, [키워드] Analysis biosensors Blood caused China COVID-19 current described diagnostic Future Genetic gold standard hospitals IgM/IgG immunoassay immunoassays lab lateral flow Lineage MERS-CoV methodology Microneutralization test nasopharyngeal swabs outbreak pandemic point-of-care Point-of-care devices polymerase chain precautions proteomic RT-PCR SARS-CoV SARS-CoV-2 Saudi Arabia sera Spike protein Spread Swab swab samples syndrome Treatment virus virus detection work [DOI] 10.3390/s20154289 PMC 바로가기 [Article Type] Review
From Anti-SARS-CoV-2 Immune Responses to COVID-19 via Molecular MimicryArticle Published on 2020-07-162022-10-27 Journal: Antibodies [Category] COVID-19, [키워드] analyzed autoantibody Autoimmune Autoimmunity composed coronavirus 2 COVID-19 cross-reactivity disorders distress epitope human protein IEDB Infection mimicry molecular mimicry multiple organ failure mutated pathologic peptide peptide sharing Perspective Protein target protein targets proteome respiratory response SARS-CoV-2 SARS-CoV-2 epitopes SARS-COV-2 infection SARS-CoV-2 pandemic sequence sera starting point Surveillance [DOI] 10.3390/antib9030033 PMC 바로가기 [Article Type] Article