sera – Page 74 – Communicable Diseases Research

Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus Pseudotypes

Article

Published on 2020-07-152022-10-28
Journal: Vaccines [Category] COVID-19,

[키워드] acute respiratory syndrome analyzed antibodies antiviral therapy approved biosafety Biosafety Level 3 can be used caused classical coefficient convalescent COVID-19 patient convalescent COVID-19 patients coronavirus correlated detect determine displaying genus Betacoronavirus homologous Immune status morbidities MOST neutralization titer neutralized Neutralizing antibodies neutralizing antibody Neutralizing antibody titer pandemic virus passive immunization patient cohort Pearson correlation performed pseudotype virus pseudovirus quantification Rapid robust SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 neutralization SARS-CoV-2-neutralizing antibodies SARS-CoV-2-neutralizing antibody sera serum Spike protein the SARS-CoV-2 therapeutic vaccinated individuals Vaccine Vaccines vesicular vesicular stomatitis virus VSV
[DOI] 10.3390/vaccines8030386 PMC 바로가기 [Article Type] Article

SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

Article

Published on 2020-07-142022-10-04
Journal: Nature Communications [Category] SARS, 임상, 진단, 치료기술, 치료법,

Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice

Article

Published on 2020-07-092022-10-29
Journal: Nature Communications [Category] COVID-19, SARS,

Serological differentiation between COVID-19 and SARS infections

COVID-19와 SARS 감염의 혈청학적 구별

Research Article

Published on 2020-07-072022-08-13
Journal: Emerging Microbes & Infections [Category] MERS, SARS, 임상,

[키워드] acute disease anti-N antibodies Anti-RBD antibodies antibody antibody tests asymptomatic infection rate asymptomatic infection rates best Betacoronavirus Blood capture caused choice Contact tracing Coronaviridae coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 antibody test COVID-19 antibody tests cross-reactivity diagnostic diagnostic test diagnostic tests Disease diagnosis ELISA family Coronaviridae genus genus Betacoronavirus herd immunity humans Immunity infect Infection N protein offer other coronavirus outbreak PCR PCR test PCR tests performed protective immunity Protein RBD region required SARS SARS infection SARS patient SARS-CoV SARS-CoV-2 sequence identity sera serological test Serological tests serology significant level species specificity survivor virus waned while
[DOI] 10.1080/22221751.2020.1780951 PMC 바로가기 [Article Type] Research Article

Immune Phenotyping Based on the Neutrophil-to-Lymphocyte Ratio and IgG Level Predicts Disease Severity and Outcome for Patients With COVID-19

Molecular Biosciences

Published on 2020-07-032022-10-31
Journal: Frontiers in Molecular Biosciences [Category] COVID-19,

[키워드] acute respiratory syndrome Analysis antibody Antibody Response calculated CD4+ T cell characterized chemiluminescence CLIA Clinical deterioration Clinical outcome complementary coronavirus disease Coronavirus-2 COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity Cytokine storm disease disease severity IgG IgG and IgM IgG level IgG levels IgG response IL-10 IL-2 IL-6 immune response Inflammatory cytokine initiated Level Neutrophil-to-lymphocyte ratio NLR non-severe patients occurred outcome outcomes Patient phenotype Phenotypes Phenotyping predict Ratio Respiratory disease robust SARS-CoV-2 sera Severe patient single center Spread stratified Wuhan
[DOI] 10.3389/fmolb.2020.00157 PMC 바로가기 [Article Type] Molecular Biosciences

The common personal behavior and preventive measures among 42 uninfected travelers from the Hubei province, China during COVID-19 outbreak: a cross-sectional survey in Macao SAR, China

Health Policy

Published on 2020-06-192022-10-28
Journal: PeerJ [Category] COVID-19,

[키워드] age analyzed antibodies Behavior caused Characteristics children China city composed conducted confirmed case Contact country COVID-19 COVID-19 cases cross-sectional survey cumulative mortality death diagnosed with COVID-19 disease effective exclusion female Government hands with soap handwashing high-risk activity highest hygiene identify individuals ineligible Infant information lockdown mandatory quarantine Mask nasopharyngeal specimen novel coronavirus disease organized outbreak over Prevalence prevention preventive measure preventive measures proportion quarantine questionnaire Result RNA SAR SARS-CoV-2 sera significant increase Social distance Traffic ban uninfected Wuhan
[DOI] 10.7717/peerj.9428 PMC 바로가기 [Article Type] Health Policy

Potential Antiviral Options against SARS-CoV-2 Infection

Article

Published on 2020-06-132022-10-28
Journal: Viruses [Category] COVID-19, SARS,

The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

Research Articles

Published on 2020-06-112022-10-28
Journal: Science Immunology [Category] COVID-19, Fulltext, SARS, 조류인플루엔자,

[키워드] acute respiratory syndrome antibody Antigen can be used Clinical symptoms clinically conserved contagious control subjects coronavirus correlation diagnostic evaluate human sera hyperimmune identify immunodominant individual infected individuals Mild onset of symptoms pandemic pathogenic human coronaviruses patients PCR testing population level RBD RBD binding antibody RBD-binding antibody Receptor binding domain Recombinant SARS-CoV-2 RBD responsible SARS-CoV SARS-CoV-2 SARS-CoV-2 antibody responses SARS-CoV-2 neutralization SARS-CoV-2 neutralizing antibody SARS-CoV-2 patient SARS-CoV-2-specific antibodies sera serologic test serological Serum level severe disease severe respiratory illness Spread Support Surveillance symptomatic patient the RBD the spike protein Viral RNA viral spike protein virus virus infection zoonotic CoV
[DOI] 10.1126/sciimmunol.abc8413 PMC 바로가기 [Article Type] Research Articles

Diagnostic performance of immunochromatography assay for rapid detection of IgM and IgG in coronavirus disease 2019

Research Article

Published on 2020-06-092022-10-04
Journal: Journal of medical virology [Category] 진단,

Immunization with porcine epidemic diarrhea virus harbouring Fc domain of IgG enhances antibody production in pigs

Research Article

Published on 2020-06-082022-10-28
Journal: The Veterinary Quarterly [Category] Coronavirus, MERS,

[키워드] addition Analysis antibody production Cell collected coronavirus crossbred cytokine domain Efficacy ELISA ENhance epidemic diarrhea evaluated experiment expressing facilitate Fc IFN-γ IgG IgG Fc immune response immunization inactivated Inactivated vaccine Infection intramuscularly negative controls Neutralizing objective PEDV Porcine Porcine epidemic diarrhea Prevent Protective Result resulting sera serum serum sample significantly higher significantly increased Spread swine t-test TCID two-tailed Vaccine vaccine candidate Vero Cell virion virus was performed were used
[DOI] 10.1080/01652176.2020.1773006 PMC 바로가기 [Article Type] Research Article