Clinical course and predictors of 60-day mortality in 239 critically ill patients with COVID-19: a multicenter retrospective study from Wuhan, ChinaResearch Published on 2020-07-062022-11-01 Journal: Critical Care [Category] COVID-19, [키워드] Acute cardiac injury Acute kidney injury acute respiratory distress acute respiratory syndrome age AKI ARDS association clinical Clinical course clinical outcomes Coagulopathy collected Complication confirmed case Course COVID-19 Critically ill Critically ill patient Deceased hospital ICU admission ICUs identify information intensive care unit Laboratory median Mortality multicenter Negative conversion occurred Older Patient patients patients with COVID-19 predicted predictor preexisting comorbidities regression analysis Result Retrospective study SARS-CoV-2 IgM SARS-CoV-2 RNA serum severity survivor symptom onset syndrome thrombocytopenia with COVID-19 Wuhan, China [DOI] 10.1186/s13054-020-03098-9 PMC 바로가기 [Article Type] Research
Effect of hypertension on outcomes of adult inpatients with COVID-19 in Wuhan, China: a propensity score–matching analysisResearch Published on 2020-07-062022-10-28 Journal: Respiratory Research [Category] COVID-19, [키워드] 95% CI Analysis applied chronic Comorbidity COVID-19 COVID-19 patient critically ill patients D-dimer D-dimer level death died discharge Effect enrolled hazard ratio Hospitalized hypertension Increased increased mortality increased risk Inpatient Laboratory lymphocyte Mortality N/L neutrophil non-survivor outcome outcomes participant Patient patients with COVID-19 patients’ mortality previous study Propensity score–matching analysis proportion PSM question radiological Result risk severe COVID-19 shown survived survivor with COVID-19 Wuhan Wuhan, China [DOI] 10.1186/s12931-020-01435-8 PMC 바로가기 [Article Type] Research
Dynamic changes of D-dimer and neutrophil-lymphocyte count ratio as prognostic biomarkers in COVID-19Research Published on 2020-07-032022-10-28 Journal: Respiratory Research [Category] COVID-19, [키워드] 95% CI acute respiratory distress age Analysis caused change China Clinical use collected data correlation count COVID-19 Cox regression Cox regression analysis Critical cut-off D-dimer death Deceased diagnosed dynamic enrolled evaluate Hospital admission Hospitalization hospitalized patient Infection initial Intubated intubated patients intubation Laboratory mortality rate much higher multivariable Cox regression Neutrophil-lymphocyte count ratio NLR non-intubated patient observé outbreak participant Patient patients patients with COVID-19 PCT Prognosis prognostic prognostic biomarker Prognostic factor pulmonary Ratio Result Retrospective study rising risk of death ROC Curve statistically survivor Symptom syndrome the patient utility with COVID-19 Wuhan [DOI] 10.1186/s12931-020-01428-7 PMC 바로가기 [Article Type] Research
Longitudinal hematologic and immunologic variations associated with the progression of COVID-19 patients in ChinaResearch article Published on 2020-07-012022-10-05 Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 바이오마커, [키워드] Admission analyzed association basophils Biomarker C-reactive protein CD8+ T-cell changes in China Cohort coronavirus disease correlation COVID-19 COVID-19 patient D-dimer Deceased discharged dropped eosinophils hematologic Hematologic indices Hospitalization IL-6 immunologic response immunologic responses impairment Increased increases in longitudinal lymphocyte Lymphocytes multivariate Cox regression National neutrophil count Neutrophils nonsurvivor nonsurvivors objective outcome patients patients with COVID-19 Platelet predict predictor predominant procalcitonin progression Protein restored Result Retrospective study severity significantly suggested survivor Survivors T-cell Variation was performed [DOI] 10.1016/j.jaci.2020.05.003 [Article Type] Research article
Prevalence and impact of acute renal impairment on COVID-19: a systematic review and meta-analysisResearch Published on 2020-06-182022-11-01 Journal: Critical Care [Category] COVID-19, SARS, [키워드] 2019-nCoV 95% CI Acute kidney injury AKI Analysis association Continuous Continuous renal replacement therapy COVID-19 COVID-19 patient COVID-19 patients critical cases CRRT database determine eligible incidence kidney dysfunction Meta-analysis Mild moderate non-severe patient non-survivor Non-survivors Patient patients Prevalence proportion renal impairment renal replacement therapy reported required Result SARS-CoV-2 searched severe cases severe patients severity and prognosis survivor Survivors systematic review Urine was performed [DOI] 10.1186/s13054-020-03065-4 PMC 바로가기 [Article Type] Research
Mental health status and related influencing factors of COVID‐19 survivors in Wuhan, ChinaLetter to Editor Published on 2020-06-052022-10-31 Journal: Clinical and Translational Medicine [Category] COVID-19, [키워드] COVID‐19 COVID‐19 Factor follow‐up Health status mental health survivor Survivors Wuhan, China [DOI] 10.1002/ctm2.52 PMC 바로가기 [Article Type] Letter to Editor
Plasma albumin levels predict risk for nonsurvivors in critically ill patients with COVID-19Research Article Published on 2020-06-032022-10-28 Journal: Biomarkers in Medicine [Category] COVID-19, SARS, [키워드] albumin albumin level association Biomarker Biomarkers Confirmed COVID-19 infection confounding factors COVID-19 Critical Critically ill patient critically ill patients Disease progression hospitalized patient increase in independent Infection material moderate nonsurvivor nonsurvivors plasma Platelet Pneumonia predict risk severity of COVID-19 survivor with COVID-19 [DOI] 10.2217/bmm-2020-0254 PMC 바로가기 [Article Type] Research Article
Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-ReviewCOVID-19 치료에 대한 클로로퀸 및 하이드록시클로로퀸 이독성의 임상적 의미: 미니 리뷰Review Published on 2020-05-292022-09-11 Journal: Frontiers in Public Health [Category] SARS, 치료제, [키워드] auditory Autoimmune diseases Characteristics Chloroquine clinical clinical trial clinical trials COVID-19 COVID-19 infection COVID-19 pandemic damage dose drug dysfunction Effect effective greater hearing loss Hydroxychloroquine hydroxychloroquine treatment Imbalance implication inner ear Intervention lAbel malaria Newborn off-label off-label use ototoxic ototoxicity pregnant women protocol reported sensorineural hearing loss structures suggested survivor tinnitus treated Treatment Trial urgent investigation usual dosage [DOI] 10.3389/fpubh.2020.00252 PMC 바로가기 [Article Type] Review
The potential long-term impact of the COVID-19 outbreak on patients with non-communicable diseases in Europe: consequences for healthy ageingReview Published on 2020-05-262022-10-28 Journal: Aging Clinical and Experimental Research [Category] COVID-19, MERS, SARS, [키워드] Affect change Chronic diseases clinical conditions Clinical symptoms communicable consequence Containment measure coronavirus country COVID-19 COVID-19 outbreak COVID-19 pandemic Diagnosis disease early stage elderly frailty healthcare Healthcare systems healthy implication IMPROVE individual individuals infection control management measure medication mental health disorders mitigate mortality risk NCD Non-communicable disease outbreak Patient patients physical activity progression quarantine reduce risk factor SARS-CoV-2 SARS-COV-2 infection severity of COVID-19 social distancing survivor to define Treatment strategies vitamin D level while worsening [DOI] 10.1007/s40520-020-01601-4 PMC 바로가기 [Article Type] Review
Novel Insights Into Illness Progression and Risk Profiles for Mortality in Non-survivors of COVID-19Medicine Published on 2020-05-222022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Acute cardiac injury Acute kidney injury age analyzed ARDS biochemical Biochemical parameters bleeding CD3 CD4 CD8 cells changes in clinical picture Cohort complete clinical course COVID-19 D-dimer death Deterioration Diagnosis disease disease onset Disease progression elevated epidemiological exhibited Hospital admission illness immune dysregulation immune parameter indicated Infection initial insight Intervention intestine IQR Kaplan–Meier Leukocytosis lymphopenia male median Mortality non-survivor Non-survivors novel outbreak Patient patients died patients with COVID-19 Peripheral blood procalcitonin profile progression proportion Result risk SARS-CoV-2 severe complications Shock significantly suffered survival survivor T lymphocyte the disease the median Wuhan [DOI] 10.3389/fmed.2020.00246 PMC 바로가기 [Article Type] Medicine