Nontyphoidal salmonella disease: Current status of vaccine research and development비타이프 살모넬라 질병: 백신 연구 및 개발의 현재 상태journal-article Published on 2016-06-012024-07-30 Journal: Vaccine [Category] 살모넬라증, [키워드] Africa developing countries iNTS disease Pediatric infections S. Enteritis S. Typhimurium Salmonella Salmonella infections Vaccine development [DOI] 10.1016/j.vaccine.2016.03.072 [Article Type] journal-article
Status of paratyphoid fever vaccine research and development파라티푸스 백신 연구 및 개발 현황journal-article Published on 2016-06-012024-07-30 Journal: Vaccine [Category] 살모넬라증, [키워드] developing countries Enteric fever paratyphoid fever Salmonella Salmonella paratyphi salmonella paratyphi a Vaccine development vaccine policy Vaccines [DOI] 10.1016/j.vaccine.2016.03.106 [Article Type] journal-article
Deciphering the biology of porcine epidemic diarrhea virus in the era of reverse geneticsArticle Published on 2016-05-202022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] addressed approach association BAC Biological Cell culture cell line cell lines clone complementary disease disease phenotype emergence epidemic diarrhea function Genetic genetics help highlight identify implication in vitro lack less mitigate modulating nucleocapsid nucleocapsid protein ORF3 Pathogenesis pathogenic mechanisms pathogenicity PEDV Porcine epidemic diarrhea virus question reverse genetics RNA recombination Spike protein the spike protein Vaccine Vaccine development viral life cycle viral tropism virulence virus [DOI] 10.1016/j.virusres.2016.05.003 PMC 바로가기 [Article Type] Article
A trivalent vaccine candidate against hepatitis E virus, norovirus, and astrovirusArticle Published on 2016-02-102023-06-12 Journal: Vaccine [Category] E형 간염, Fulltext, [키워드] astrovirus hepatitis E virus Norovirus Oligomeric complex Trivalent vaccine Vaccine development vaccine platform [DOI] 10.1016/j.vaccine.2015.12.068 PMC 바로가기
Malaria invasion ligand RH5 and its prime candidacy in blood-stage malaria vaccine designarticle Published on 2015-12-312024-09-01 Journal: Human vaccines & immunotherapeutics [Category] 말라리아, [키워드] Invasion Malaria vaccine Plasmodium falciparum RH5 Vaccine development [Article Type] article
Epitope-Based Vaccine Target Screening against Highly Pathogenic MERS-CoV: An In Silico Approach Applied to Emerging Infectious DiseasesResearch Article Published on 2015-12-072022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] alleles Analysis B-cell B-cell epitope candidate Cellular immune response Coverage CTL CTL epitope CTL epitopes cytotoxic T lymphocyte Diseases dominant effective elicit epitope helper T-cell epitope helper T-cell epitopes HLA binding Immune Epitope Database Immunity immunogen induce Infectious disease linear majority mapped MERS MERS-CoV Middle East neutralizing antibody nucleocapsid pandemic pathogen peptide Population Protective protective neutralizing antibody Protein provide public health Region respiratory syndrome coronavirus screened Screening screening strategy selected sequence T-cell T-cell Response target the N protein Vaccine vaccine candidates Vaccine development was performed [DOI] 10.1371/journal.pone.0144475 PMC 바로가기 [Article Type] Research Article
Discovery of Immunodominant B Cell Epitopes within Surface Pneumococcal Virulence Proteins in Pediatric Patients with Invasive Pneumococcal Disease소아 침습성 폐렴구균 질환 환자에서 표면 폐렴구균 독성 단백질 내 면역지배 B 세포 에피토프의 발견journal-article Published on 2015-11-012024-08-04 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] epitope mapping Pneumonia Streptococcus Vaccine development zinc finger [DOI] 10.1074/jbc.M115.666818 [Article Type] journal-article
Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibodyArticle Published on 2015-09-152022-10-29 Journal: Nature Communications [Category] Coronavirus, [키워드] antibody binding complex Critical domain epitope Fab healthy high affinity Human implication in vivo information Interaction m336 mechanism MERS-CoV Mortality Mutation neutralization overlap provide residue reveal structural biology supplementary material Vaccine development vaccine immunogen viral infection virus Virus structures [DOI] 10.1038/ncomms9223 PMC 바로가기 [Article Type] Article
Purification and characterization of aShigellaconjugate vaccine, produced by glycoengineeringEscherichia coli글리코공학 에셔리키아 콜리를 이용하여 생산된 시겔라 접합 백신의 정제 및 특성 분석journal-article Published on 2015-09-102024-07-30 Journal: Glycobiology [Category] 세균성이질, [키워드] biosynthetic glycoconjugate vaccine E. coli glycosylation O-polysaccharide Shigella dysenteriae type 1 Vaccine development [DOI] 10.1093/glycob/cwv077 [Article Type] journal-article
Evaluation of candidate vaccine approaches for MERS-CoVArticle Published on 2015-07-282022-10-29 Journal: Nature Communications [Category] Coronavirus, MERS, [키워드] Analysis antibodies approach atomic candidate vaccine complex Computerized tomography CoV demonstrated DNA effective elicit full-length S glycoprotein highlight immunization immunogen information Isolation mechanism MERS-CoV mice Middle East monoclonal antibody Multiple murine NAb neutralization neutralizing antibody non-human primates Pneumonia Protein Radiographic RBD respiratory syndrome coronavirus responses rhesus macaque robust S variant S1 and S2 S1 subunit Sequencing serological assays severe respiratory disease spike strain subunit supplementary material the receptor-binding domain Vaccine Vaccine development Vaccines viral infection Virology virus [DOI] 10.1038/ncomms8712 PMC 바로가기 [Article Type] Article