Sequence features governing aggregation or degradation of prion-like proteins
프리온 유사 단백질의 응집 또는 분해를 제어하는 서열 특징
Research Article
[키워드] aggregate
aggregates
aggregation
aliphatic
Alzheimer’s disease
Amino acid
amino acid sequence
amino acids
Amyotrophic lateral sclerosis
aromatic residue
aromatic residues
asparagine
cellular
classical
clearance
complex interplay
control systems
correlated
Degradation
Diseases
domain
domains
dose-dependent
elicited
enhanced
eukaryotic
evade
Factor
Factors
feature
Features
Frequency
Genetic
genetic screen
Glutamine
glycine
highlight
hnRNPA1
human protein
human proteins
increase in
intrinsic
Lateral Sclerosis
lead
neurodegenerative disorder
neurodegenerative disorders
occur
Prevent
promote
promoted
Protein
protein quality control
Proteins
Quality control
recognize
recognizing
residue
second
sequence
stimulate
subset
suppressed
to define
variety
while
yeast
[DOI] 10.1371/journal.pgen.1007517 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.pgen.1007517 PMC 바로가기 [Article Type] Research Article