Murine-β-coronavirus-induced neuropathogenesis sheds light on CNS pathobiology of SARS-CoV2Review Published on 2021-04-012023-08-30 Journal: Journal of Neurovirology [Category] E형 간염, [키워드] Acute myelitis coronavirus Cytokine storm Encephalitis IFNs lymphocytopenia m-CoV. MHV Myelin loss in the CNS and PNS) Neurological manifestations (meningitis SARS-CoV2 Spike protein Virus persistence [DOI] 10.1007/s13365-021-00945-5 PMC 바로가기 [Article Type] Review
COVID-19 is associated with clinically significant weight loss and risk of malnutrition, independent of hospitalisation: A post-hoc analysis of a prospective cohort studyObservational Study Published on 2021-04-012022-10-05 Journal: Clinical nutrition (Edinburgh, Scotland) [Category] SARS, 임상, [키워드] Admission age alteration Analysis biochemical parameter C-reactive protein clinic clinical manifestations clinically collected Coronavirus disease 2019 Course COVID-19 COVID-19 patients demographic Department diagnosis of COVID-19 discharged home disease Emergency enrolled females Follow-up greater hospitalised hospitalised patient incidence independent initial initial body institution intensive care lost weight Malnutrition median median age multivariate logistic regression Nutritional evaluation nutritional status Outpatient Outpatient management overweight/obese Patient post-hoc analysis predicted prospective cohort study prospective observational cohort renal function risk SARS-CoV2 Severe respiratory distress Survivors systemic inflammation Treatment university Visual Analogue Scale weight weight loss were assessed [DOI] 10.1016/j.clnu.2020.10.043 PMC 바로가기 [Article Type] Observational Study
Rare SARS-CoV-2 antibody development in cancer patients암 환자에서 희귀 SARS-CoV-2 항체 개발Article Published on 2021-04-012022-09-11 Journal: Seminars in oncology [Category] MERS, SARS, 진단, 치료기술, [키워드] adaptive analyzed antibody antibody concentration assumed bead BGI Cancer cancer patient CAST Course COVID-19 develop Diagnosis doubt extraction humoral Hypothesis Immunity immunoassay individual infected with SARS-CoV-2 knowledge MERS-CoV multiple testing other coronaviruses pandemic Pathogenesis Patient positive provided qPCR Roche RT-qPCR SARS-CoV SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV2 SARS-CoV2 antibody development. SARS-CoV2 infection subsequent understanding Vaccine development were used [DOI] 10.1053/j.seminoncol.2020.12.003 PMC 바로가기 [Article Type] Article
Parsonage-turner syndrome associated with SARS-CoV2 (COVID-19) infectionCase Reports Published on 2021-04-012023-07-11 Journal: Clinical imaging [Category] SARS, [키워드] Acute idiopathic brachial neuritis multisystem inflammatory syndrome in children (MIS-C) Neuralgic amyotrophy Parsonage-Turner Syndrome SARS-CoV2 Shoulder-girdle syndrome. [DOI] 10.1016/j.clinimag.2020.11.017 PMC 바로가기 [Article Type] Case Reports
COVID-19: Between Past and PresentReview Published on 2021-04-012023-07-06 Journal: Viral immunology [Category] SARS, [키워드] coronavirus COVID-19 Cytokine storm immunopathology SARS-CoV2 therapy [DOI] 10.1089/vim.2020.0102 [Article Type] Review
Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein내피 세포 손상은 COVID-19의 중심 부분이며 스파이크 단백질의 S1 서브유닛을 주입하여 유도된 마우스 모델Article Published on 2021-04-012022-09-11 Journal: Annals of diagnostic pathology [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] ACE2 Analysis Autopsy Behavior Brain Brain tissues C5b-9 caspase caspase 3 caspase-3 cell damage Complication COVID-19 demonstrated detect diagnostic died endothelial Endothelial cell endothelial cell damage endothelial damage envelope eosin examined fatal COVID-19 full length hematoxylin Hematoxylin and eosin host response IL6 immunohistochemistry increased thirst incubated injected injection Localization membrane protein Membrane proteins MFSD2a mice neurologic neurologic signs Neuron neuronal neuronal cell neuronal cells NOS pathologist pathology positive Protein Proteins pseudovirion pseudovirions S1 subunit S2 subunit SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV2 SHIP1 spike Spike protein subunit subunits symptomatic symptomatic COVID-19 tail the S1 subunit the spike protein tissue TNFα Viral RNA were used wild type [DOI] 10.1016/j.anndiagpath.2020.151682 PMC 바로가기 [Article Type] Article
RAMIC: Design of a randomized, double-blind, placebo-controlled trial to evaluate the efficacy of ramipril in patients with COVID-19RAMIC: COVID-19 환자에서 라미프릴의 효능을 평가하기 위한 무작위, 이중 맹검, 위약 대조 시험 설계Article Published on 2021-04-012022-09-11 Journal: Contemporary clinical trials [Category] MERS, SARS, 바이오마커, 임상, [키워드] ACE Adult patients angiotensin Complication composite endpoint coronavirus disease Coronavirus disease 2019 COVID-19 death decrease diastolic double-blind Efficacy emergency department Endpoint evaluate exclusion criteria filtration rate glomerular filtration rate hospital ICU admission include Informed consent inhibitor Invasive mechanical ventilation Mechanical mechanical ventilation mechanical ventilator mitigate Mortality multicenter Novel coronavirus novel coronavirus disease occur patients with COVID-19 Personal protective equipment Placebo placebo-controlled trial PPE primary composite endpoint ramipril Randomized receive reduced risk risk risk of infection risk of transmission SARS-CoV-2 transmission SARS-CoV2 shown study population study visit Systolic blood pressure Treatment Virtual visit. [DOI] 10.1016/j.cct.2021.106330 PMC 바로가기 [Article Type] Article
Cardiovascular Complications of COVID-19: Pharmacotherapy PerspectiveCOVID-19의 심혈관 합병증: 약물 요법의 관점Review Published on 2021-04-012022-09-11 Journal: Cardiovascular Drugs and Therapy [Category] SARS, 치료제, [키워드] 2019 Acute coronary syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered anti-inflammatory agents approved Arrhythmias cardiovascular cardiovascular complication cardiovascular complications cardiovascular disease caused Complication coronary syndrome coronavirus coronavirus disease COVID-19 COVID-19 infection Dexamethasone disease drug Drug–drug interactions Evidence Health Organization healthy individual heart failure Hydroxychloroquine increased risk Interaction medication morbidity Mortality myocarditis Patient patients with COVID-19 pharmacotherapy problem protease inhibitors Remdesivir SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 severe acute respiratory syndrome Coronavirus therapy Thromboembolism Treatment Venous Thromboembolism World Health Organization [DOI] 10.1007/s10557-020-07037-2 PMC 바로가기 [Article Type] Review
Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Acute Admissions at the Emergency and Cardiology Departments Across EuropeObservational Study Published on 2021-04-012022-10-05 Journal: The American journal of medicine [Category] SARS, 임상, [키워드] 95% confidence interval Acute cardiovascular admissions Acute coronary syndrome Acute heart failure acute respiratory syndrome Admission Admissions analyzed arrhythmia Cardiology changes in collected coronary syndrome coronavirus COVID-19 COVID-19 outbreak death Department Emergency Europe European evaluated Impact incidence rate multicenter Myocardial Odds ratio outbreak pandemic Patient provided risk risk of death SARS-CoV2 [DOI] 10.1016/j.amjmed.2020.08.043 PMC 바로가기 [Article Type] Observational Study
The treatment of SARS-CoV2 with antivirals and mitigation of the cytokine storm syndrome: the role of gene expressionReview Published on 2021-04-012023-07-11 Journal: Genome [Category] SARS, [키워드] Cytokine release syndrome Cytokine storm syndrome drug treatment epigenetics épigénétique. expression génique Gene Expression SARS-CoV2 syndrome de choc cytokinique syndrome de libération de cytokines traitement pharmacologique [DOI] 10.1139/gen-2020-0130 [Article Type] Review