eight – Page 78 – Communicable Diseases Research

Early prediction keys for COVID-19 cases progression: A meta-analysis

Review article

Published on 2021-05-012022-10-05
Journal: Journal of infection and public health [Category] SARS, 바이오마커,

Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial

인도에서 중등도에서 중증의 COVID-19 관련 사이토카인 방출 증후군(COVINTOC) 환자에 대한 토실리주맙과 표준 치료 대 표준 치료: 공개, 다기관, 무작위 배정, 대조, 3상 시험

Clinical Trial

Published on 2021-05-012022-09-12
Journal: The Lancet. Respiratory Medicine [Category] Fulltext, SARS, 임상, 진단,

[키워드] 1:1 Action acute respiratory distress adverse event adverse events analyses anti-IL-6 receptor antibody assigned baseline Block randomisation Cipla clinical country COVID-19 COVID-19 progression Cytokine release syndrome death decrease discharge education effective eight Evidence FIVE Follow-up grade 3 hospital India intensive care investigated mechanical ventilation medication Ministry of Health moderate modified intention-to-treat multicentre occurred one patient Open-label participant Patient patients died phase 3 trial positive SARS-CoV-2 PCR post-hoc Prevent primary endpoint progression Racial randomised randomised controlled trial Randomly randomly assigned patients receive recruited reduced Registered registry reported Roche routine Safety Serious Adverse Events Seven severe COVID-19 shown standard care standard care group supported syndrome the primary endpoint Tocilizumab Treatment Trial with COVID-19
[DOI] 10.1016/S2213-2600(21)00081-3 PMC 바로가기 [Article Type] Clinical Trial

Coronavirus Disease (Covid-19) Associated Mucormycosis (CAM): Case Report and Systematic Review of Literature

코로나바이러스 감염증(Covid-19) 관련 점막진균증(CAM): 사례 보고 및 문헌의 체계적인 검토

Case Reports

Published on 2021-05-012022-09-11
Journal: Mycopathologia [Category] 치료제,

[키워드] Admission Amphotericin amphotericin B CAPA complicate concurrent coronavirus disease Course COVID-19 Dexamethasone diabetes Diabetes Mellitus diagnosed died discharged eight Fungal infection glucocorticoid Glucocorticoids had no higher risk hospital Hospitalization IMPROVE increasingly index case Infection Kidney disease literature management Mucorales Mucormycosis outcomes patients performed pulmonary aspergillosis Pulmonary mucormycosis report required review risk risk factor Seven severe coronavirus disease severe COVID-19 subject suspicion systematic review systemic glucocorticoids therapy Tocilizumab Two subjects while Zygomycosis
[DOI] 10.1007/s11046-021-00528-2 PMC 바로가기 [Article Type] Case Reports

Exacerbation of Inequities in Use of Diagnostic Radiology During the Early Stages of Reopening After COVID-19

Research article

Published on 2021-05-012022-10-05
Journal: Journal of the American College of Radiology : JAC [Category] SARS, 진단,

The Evolution in Anxiety and Depression with the Progression of the Pandemic in Adult Populations from Eight Countries and Four Continents

Article

Published on 2021-05-012022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, SARS,

[키워드] adjusted odds ratio age Anxiety Belgium build Canada caused conducted continent continuum contributed contributing to country COVID-19 outbreak depressive disorder eight England Evolution examined exceeded Factor Factors GAD global pandemic Health healthcare Hong Kong increase in independent indicated infodemic Intervention Logistic regression mental health New pandemic phase Population progression proportion Protective Psychological psychological disorders Psychosocial impact Psychosocial impacts public health measure rising sense of coherence Switzerland The United States Variation were assessed
[DOI] 10.3390/ijerph18094845 PMC 바로가기 [Article Type] Article

Convalescent plasma treatment of critically ill intensive care COVID-19 patients

중환자 중환자실 COVID-19 환자의 회복기 혈장 치료

Clinical Trial

Published on 2021-05-012022-09-11
Journal: Transfusion [Category] MERS, SARS, 비임상, 임상, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus All the patient all the patients antibody antiviral drug antiviral drugs antiviral immune response applied average breath Clinical outcome Complication convalescent plasma treatment coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill COVID-19 patients Deceased determined by died effective Efficacy eight enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Euroimmun FFP transfusion FIVE IgG IgG antibody immune responses Immunoglobulin Immunoglobulin G IMPROVE indicated Infectious disease infectious disease testing intensive care Intravenous immunoglobulin investigated life-threatening median multiple organ failure Neutralization assay Neutralizing titer neutralizing titers onset of symptoms organ Organ failure Patient patient survival patients plasma respiratory S1 protein SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody sera Seven severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specific antibodies survivor the S1 protein treated Treatment
[DOI] 10.1111/trf.16392 PMC 바로가기 [Article Type] Clinical Trial

What Proportion of Patients with Bone and Soft Tissue Tumors Contracted Coronavirus-19 and Died From Surgical Procedures During the Initial Period of the COVID-19 Pandemic? Results From the Multicenter British Orthopaedic Oncology Society Observational Study

Observational Study

Published on 2021-05-012022-10-05
Journal: Clinical orthopaedics and related research [Category] SARS, 임상,

[키워드] 48 hour addition adjuvant therapy Admission age agency analyzed association Asymptomatic benefit bone Cancer Cancer center cancer treatment Care Chemotherapy clinician Complication contracting the virus Coronavirus 2019 COVID-19 COVID-19 in patient COVID-19-related complications detrimental eight England Factor FIVE Follow-up Future help hospital Hospital stay identify Increased increased mortality increased risk initial knowledge Level likelihood lower risk management mandatory measure median men Mortality Musculoskeletal National National Health Service Odds ratio oncology outcome outcomes pandemic Patient patients died PCR testing performed Period potential risk Primary outcome procedure Radiation reduce Result retrospective risk secondary outcome Society Soft surgeon surgical Surgical Procedure susceptibility tested the median therapeutic therapy tissue treated Treatment Tumor undergo United Kingdom were used
[DOI] 10.1097/CORR.0000000000001568 PMC 바로가기 [Article Type] Observational Study

Impaired performance of SARS-CoV-2 antigen-detecting rapid diagnostic tests at elevated and low temperatures

고온 및 저온에서 SARS-CoV-2 항원 검출 신속 진단 검사의 성능 저하

Article

Published on 2021-05-012022-09-10
Journal: Journal of Clinical Virology [Category] 진단, 치료기술,

[키워드] Ag-RDT Ag-RDTs ambient ambient temperatures analytical sensitivity Antigen Antigen-detecting rapid diagnostic tests Cell culture cell culture supernatant clinically complement condition conditions consequence COVID-19 culture supernatant diagnostic tests diagnostics eight elevated elevated temperature Emergency use exhibited exposure to false-negative false-positive result False-positive results FIVE Genome Health Organization Highlights impair Impaired include Incubation limit limits Limits of detection low temperature Low temperatures mean temperature mean temperatures molecular molecular diagnostics North not affected occurred operation pandemic quarantine ranged rapid antigen test Rapid diagnostic test RDTs reduce reduced respiratory respiratory virus respiratory viruses SARS-CoV-2 SARS-CoV-2 cell sensitivity South specificity storage temperature Temperature stability test results tested the WHO Transmission Tropics virus concentration Virus concentrations viruses Winter World Health Organization
[DOI] 10.1016/j.jcv.2021.104796 PMC 바로가기 [Article Type] Article

Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and Other Coronaviruses: A Genome-wide Comparative Annotation and Analysis

Comparative Study

Published on 2021-05-012022-10-04
Journal: Molecular and cellular biochemistry [Category] SARS, 신약개발,

[키워드] alleviate Analysis analyzed annotation cause Comparative coronavirus coronavirus 2 COVID-19 death develop diagnostic difficulty in breathing disease dry cough eight facilitate Factors Fatality rate Fever Genome genome map genomes genomic geographical location Host Human identify IFR include infecting Infection involved less MERS Middle East Mild Mutation mutational rate novel Other other coronavirus outbreak pandemic peptide Phylogenetic analysis Phylogenomics polymorphism predicted rate of infection researcher respiratory SARS-CoV SARS-CoV2 sequenced severe cases severe respiratory illness similarity SNP SNPs SSR Symptom transcriptional UTR UTR. virus virus infection WHO whole genome World Health Organization Wuhan
[DOI] 10.1007/s11010-020-04027-8 PMC 바로가기 [Article Type] Comparative Study

Detection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives

Short communication

Published on 2021-05-012022-10-05
Journal: Clinical microbiology and infection : the official [Category] 진단, 치료기술,

[키워드] 95% CI acute COVID-19 alleviate Antigen antigenaemia approach Blood blood draw Cohort collected COVID COVID-19 COVID-19 diagnosis detection diagnostic diagnostics eight ELISA FIVE France French limit Lower respiratory tract marker molecular assays N-antigen nasopharyngeal Nasopharyngeal samples Nasopharyngeal swab nasopharyngeal viral objective Patient patients performance plasma positive positive RT-PCR provide reagents resource Result robust RT-PCR Saliva SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 N-antigen SARS-CoV-2 nucleocapsid sensitivity serum serum sample specificity symptom onset symptoms onset tested
[DOI] 10.1016/j.cmi.2020.11.025 [Article Type] Short communication