Effects of Tanreqing Capsule on the negative conversion time of nucleic acid in patients with COVID-19: A retrospective cohort studyTanreqing Capsule이 COVID-19 환자에서 핵산의 음성 전환 시간에 미치는 영향: 후향적 코호트 연구Article Published on 2021-01-012022-08-31 Journal: Journal of integrative medicine [Category] SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] addition Administered Capsule CD3 CD4 CD45 center Chinese clinical Clinical efficacy complement conducted control group control groups coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnostic testing COVID-19 patient COVID-19 patients diagnostic diagnostic testing disease Effect fecal hospital immune laboratory-confirmed mechanism Mild moderate Moderate COVID-19 negative Negative conversion Negative conversion rate nucleic acid pandemic Patient pharyngeal Pharyngeal swab Public reductions in retrospective cohort study Shanghai Shanghai Public Health Clinical Center Significant significant reductions statistically significant difference subset T cell T cells T-cell Tanreqing Capsule. the median Therapeutic benefit Traditional Traditional Chinese medicine treated Treatment treatment group was used [DOI] 10.1016/j.joim.2020.10.002 PMC 바로가기 [Article Type] Article
Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed Infection but with Undetectable SARS-CoV-2-Specific IgGArticle Published on 2021-01-012023-07-06 Journal: Emerging Infectious Diseases [Category] SARS, [키워드] B cells cellular immunity convalescent plasma coronavirus disease COVID-19 ELISPOT PCR-confirmed infection respiratory infections SARS SARS-CoV-2 Seronegativity Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 T cells viruses zoonoses [DOI] 10.3201/2701.203772
Elevated plasma sTIM-3 levels in patients with severe COVID-19중증 COVID-19 환자의 혈장 sTIM-3 수치 상승Clinical Trial Published on 2021-01-012022-09-11 Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 바이오마커, 임상, [키워드] activated Activated neutrophils activated T cell activated T cells Activation analyzed association CD25 Clinical outcome coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 infection disease severity disorder downregulation dysregulation examined Exhaustion fraction high plasma level high plasma levels Hospital admission ICU ICU treatment immune activation immune dysregulation Immunoglobulin Infection intensive care intensive care unit leukocyte macrophage activation marker monocyte mucin myeloperoxidase N-terminal N-terminal pro-B-type natriuretic peptide neutrophil neutrophil activation Neutrophils outcome oxygen parameter Pathogenesis pathogenesis of COVID-19 Patient peptide plasma Plasma levels positively correlated pro-B-type natriuretic peptide Respiratory failure severe COVID-19 subset T cell T cells T-cell T-cell activation TIM-3 Treatment [DOI] 10.1016/j.jaci.2020.09.007 PMC 바로가기 [Article Type] Clinical Trial
Longitudinal clinical and radiographic evaluation reveals interleukin-6 as an indicator of persistent pulmonary injury in COVID-19종단 임상 및 방사선 사진 평가에서 코로나19의 지속적인 폐 손상의 지표로 인터루킨-6이 밝혀졌습니다.Research Paper Published on 2021-01-012022-09-10 Journal: International Journal of Medical Sciences [Category] MERS, 바이오마커, [키워드] Admission Analysis analyzed association B cell B cells CD19 CD4 CD8 change Chest computed tomography Chest CT Clinical management collected Computed tomography coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patients cross-sectional analysis disease course elevated evaluate expression favor feature Features follow-up period IL-6 immunological increase in independent interleukin interleukin-6 Intervention laboratory-confirmed lesion lesions longitudinal Lung injury lymphocyte Lymphocytes Mild moderate Multivariate analysis neutrophil Neutrophils outcome Patient patients Peripheral blood Peripheral blood sample peripheral blood samples Previous studies previous study Prolonged pulmonary injury pulmonary lesion pulmonary lesions Radiographic rationale reveal scored semi-quantification sequential monitoring Severe patient severe patients significantly sustained T cells the disease [DOI] 10.7150/ijms.49728 PMC 바로가기 [Article Type] Research Paper
How could we forget immunometabolism in SARS-CoV2 infection or COVID-19?Review Published on 2021-01-012023-07-12 Journal: International reviews of immunology [Category] SARS, [키워드] B cells COVID-19 Immunity immunometabolism. SARS-CoV2 T cells [DOI] 10.1080/08830185.2020.1840567 [Article Type] Review
Cellular Immunity in COVID-19 Convalescents with PCR-Confirmed Infection but with Undetectable SARS-CoV-2–Specific IgGResearch Published on 2021-01-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, [키워드] acute respiratory syndrome analyzed antibody Antibody Response B cells blood donor cellular immunity Contact convalescent convalescent patient convalescent plasma coronavirus coronavirus disease COVID-19 detect Donor ELISA ELISPOT Frequency Germany IgG immune response Immunity infected patient Infection interferon-γ investigated negative controls onset of symptoms participant PCR-confirmed PCR-confirmed infection PCR-positive positive control respiratory infections SARS SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection Seronegativity Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 study participant T cell T cells T-cell immunity the S1 protein undetectable viruses Volunteer without symptom zoonoses [DOI] 10.3201/eid2701.203772 PMC 바로가기 [Article Type] Research
Interferon-α2b Treatment for COVID-19 Is Associated with Improvements in Lung AbnormalitiesCOVID-19에 대한 인터페론-α2b 치료는 폐 이상 개선과 관련이 있습니다Article Published on 2020-12-302022-09-10 Journal: Viruses [Category] MERS, SARS, 바이오마커, 치료제, [키워드] accelerated acute respiratory syndrome acute respiratory syndrome coronavirus age albumin Analysis ARB Arbidol C-reactive protein cause CD8+ T cell CD8+ T cells circulating clinical clinical study coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRP CT images death determine IFN treatment IFN-α2b IL-6 IL-6 levels immune parameter improvement include independent of individual Infection Inflammatory biomarker inflammatory biomarkers Inhaled interferon limit lung abnormalities lung abnormality Lung disease Moderate COVID-19 Necrosis organ Platelets predictor provided reduction in reported respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity study cohort T cell T cells the strongest therapeutic intervention treated Treatment Tumor tumor necrosis tumor necrosis factor upper airway upper airways Viral viral clearance with COVID-19 worsening [DOI] 10.3390/v13010044 PMC 바로가기 [Article Type] Article
Peripheral Blood Immune Profiling of Convalescent Plasma Donors Reveals Alterations in Specific Immune Subpopulations Even at 2 Months Post SARS-CoV-2 Infection회복기 혈장 기증자의 말초혈액 면역 프로파일링은 SARS-CoV-2 감염 후 2개월에도 특정 면역 하위 집단의 변화를 보여줍니다Article Published on 2020-12-252022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] alteration analyzed antibody B cells Blood cause CD16 CD4 CD56 CD8 characterized control subject control subjects convalescent plasma convalescent plasma donors COVID-19 COVID-19 patients deficiency Donor donors Exhaustion Follow-up full recovery Granulocytes highest Hospitalized Humoral immunity immune cells Immune profile immune profiling immune system lowest lymphocyte Lymphocytes lymphopenia Monocytes Month multiparametric flow cytometry natural killer NKT cells patients with COVID-19 peripheral Peripheral blood phenotype pro-inflammatory monocytes pro-inflammatory response Profiling promotion reduced regulatory T cells restored SARS-CoV-2 serum shown Specific subpopulations T and B cells T cells Th17 cells Th2 [DOI] 10.3390/v13010026 PMC 바로가기 [Article Type] Article
Footprint of the COVID-19 Pandemic in India: A Study of Immune Landscape and Other Factors Shielding MortalityReview Article Published on 2020-12-242022-10-28 Journal: Analytical Cellular Pathology (Amsterdam) [Category] COVID-19, Fulltext, MERS, SARS, [키워드] affected age BCG vaccination CD4 CD8 Cell contribute COVID-19 Cytotoxic T cell Ethnic groups expressed Factor favor Footprint genetic architecture Health HLA HLA ligand human leukocyte antigen immune response gene Immunity India infected cell infected cells Infection infection rates KIR KIR-HLA landscape Mortality motif natural killer NK cell function Other outbreak overexpressed pandemic polymorphism preventive measure receptor SARS-CoV-2 shown significantly significantly lower survival T cell T cells target the SARS-CoV-2 therapeutic intervention triggering Vaccination strategies virus-infected cell [DOI] 10.1155/2020/6692739 PMC 바로가기 [Article Type] Review Article
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection무증상 및 경증 SARS-CoV-2 감염에서 불일치 중화 항체 및 T 세포 반응Research Articles Published on 2020-12-232022-09-12 Journal: Science Immunology [Category] Coronavirus, MERS, SARS, 진단, [키워드] analyzed antibody Antibody Response Antibody responses Asymptomatic Asymptomatic case asymptomatic infection COVID-19 HCW healthcare worker Immunity in some individual infection with SARS-CoV-2 lockdown majority Mild mild SARS-CoV-2 infection NAb NAb titers Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing antibody responses occur pandemic reactive SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection Spike protein Symptoms symptoms of COVID-19 T cell T cell response T cell responses T cells uncoupling understanding undetectable United Kingdom [DOI] 10.1126/sciimmunol.abf3698 PMC 바로가기 [Article Type] Research Articles