Adaptive immune response – Page 8 – Communicable Diseases Research

SARS-CoV-2 Specific IgG Antibodies Persist Over a 12-Month Period in Oral Mucosal Fluid Collected From Previously Infected Individuals

SARS-CoV-2 특정 IgG 항체는 이전에 감염된 개인으로부터 수집한 구강 점막에서 12개월 동안 지속

Immunology

Published on 2021-12-092022-09-11
Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술,

Foxp3 + CD4 + regulatory T cells control dendritic cells in inducing antigen-specific immunity to emerging SARS-CoV-2 antigens

Foxp3 + CD4 + 조절 T 세포는 새로운 SARS-CoV-2 항원에 대한 항원 특이적 면역을 유도하는 수지상 세포를 제어합니다

Research Article

Published on 2021-12-092022-09-10
Journal: PLoS Pathogens [Category] SARS, 변종,

[키워드] absence activate activating acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive Adaptive immune response adaptive immune responses adjuvant adjuvants Administered administration antibody Antigen antigens approach Autoimmune diseases B cell responses CD4 CD8 cells cellular immunity Combination coronavirus DCs dendritic cell dendritic cells draining lymph node draining lymph nodes effective Efficacy ENhance examined expressing follicular FOXP3 Germinal center help helper T cell highlight humoral immune response immune responses Immunity immunological immunological tolerance IMPROVE induce initiated interferon interferon-γ investigated live SARS-CoV-2 lymph nodes maturation mechanisms mice naïve T cells neutralized Neutralizing antibodies neutralizing antibody present antigen prevented produced Protective receptor Regulatory respiratory response responses SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 spike protein SARS-CoV-2 variants self-tolerance severe acute respiratory syndrome Coronavirus Spike protein stimulate suppress T cell T cells therapy These data transcription factor Transient Treg Treg cell Treg cells vaccination Vaccine variants
[DOI] 10.1371/journal.ppat.1010085 PMC 바로가기 [Article Type] Research Article

Immuno-Endocrinology of COVID-19: The Key Role of Sex Hormones

COVID-19의 면역 내분비학: 성 호르몬의 주요 역할

Review

Published on 2021-12-022022-09-11
Journal: Frontiers in Endocrinology [Category] SARS, 유전자 메커니즘,

[키워드] Adaptive immune response androgen Clinical studies clinical study coronavirus coronavirus 2019 disease COVID-19 COVID-19 pathogenesis COVID-19 severity Cytopathic effect disease severity element Estrogen Evidence Factor Factors fatality Gender Gene regulation hormone hyper-inflammatory response identify immune response immune responses immuno-endocrinology include Infection Injury involved mechanism optimization Pathogenesis personalised regulated Regulation role SARS-CoV2 severity Sex sex hormone Sex hormones susceptibility target targets therapeutic intervention tissue injury tissue specific Treatment outcome Trial
[DOI] 10.3389/fendo.2021.726696 PMC 바로가기 [Article Type] Review

Performance of the T-SPOT Ⓡ.COVID test for detecting SARS-CoV-2-responsive T cells

SARS-CoV-2 반응성 T 세포 검출을 위한 T-SPOT Ⓡ.COVID 검사 성능

Article

Published on 2021-12-012022-09-11
Journal: International Journal of Infectious Diseases [Category] SARS, 진단, 치료기술, 치료법,

[키워드] Activation Adaptive immune response anti-N IgG Blood common cold common cold coronavirus control group coronavirus COVID-19 cross-reactive detect Diagnosis ELISPOT evaluate IGRA Immunoglobulin Infection interferon interferon-gamma release assay less methodology NAAT nucleic acid nucleic acid amplification nucleic acid amplification test nucleocapsid participant Participants participants with SARS-CoV-2 Patient peptides performance performed reactive response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike serology serology test seropositive T cell T cell response T cell responses T cells T-cell T-cells T-SPOT.COVID
[DOI] 10.1016/j.ijid.2021.09.073 PMC 바로가기 [Article Type] Article

Therapeutic mTOR blockade in systemic autoimmunity: Implications for antiviral immunity and extension of lifespan

전신 자가면역에서 치료적 mTOR 차단: 항바이러스 면역 및 수명 연장에 대한 시사점

Review

Published on 2021-12-012022-09-11
Journal: Autoimmunity reviews [Category] SARS, 치료제,

[키워드] Activation adaptive Adaptive immune response aging Antigen antigen-presenting cell antiviral immunity APC Autoimmunity blockade Cell cell fate characterized clinical Clinical effect clinical trials cognate antigen conserved contraction COVID-19 infection Critical cytokine Cytokines disease Efficacy Engagement ENhance evaluate Evidence expansion extension form Health healthy highlight Immune cell lineage specification in viral Infection Inflammation Influenza Influenza virus innate immune system Lifespan extension Lineage lupus erythematosus Mechanistic target of rapamycin mTOR pathway Plasma cell Plasma cells preliminary evidence pro-inflammatory Protective protective immunity protein complex provide provided Rapamycin receptor reduce regulatory T cells responsiveness shown Sirolimus SLE SLE patient SLE patients subjects systemic systemic lupus erythematosus T cell T cell activation T cell receptor T cells TCR Th17 Treatment Trial vaccination viral infection viral infections
[DOI] 10.1016/j.autrev.2021.102984 PMC 바로가기 [Article Type] Review

Probiotics and Coronavirus disease 2019: think about the link

Full Papers

Published on 2021-11-282022-10-28
Journal: The British Journal of Nutrition [Category] COVID-19, Fulltext, MERS, SARS,

Chapter One: Renal diseases and the role of complement: Linking complement to immune effector pathways and therapeutics

Book chapter

Published on 2021-11-262022-10-05
Journal: Advances in Immunology [Category] 비임상,

Single-Cell Immunogenomic Approach Identified SARS-CoV-2 Protective Immune Signatures in Asymptomatic Direct Contacts of COVID-19 Cases

COVID-19 사례의 무증상 직접 접촉에서 SARS-CoV-2 보호 면역 서명을 식별한 단일 세포 면역유전체학적 접근 방식

Immunology

Published on 2021-11-252022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immune response amplitude antibody Antibody titer Asymptomatic B-cell BCR CD4 CD8 Cell characterized class close contact colony stimulating factor concomitant increase Contact controls coronavirus coronavirus disease Coronavirus disease 2019 CoV COVID-19 cytokine cytokine levels Cytokines direct contact Direct Contacts Eotaxin G-CSF granulocyte granulocyte-colony stimulating factor host immunity Identified IL-7 impacted infected cases infected patients Inflammatory inhibitory interleukin Macrophage memory memory B cell memory B cells MIF Migration MIP-1α naïve T cells Neutralizing Patient patients Profiling proportion receptor reported respiratory RNA SARS-CoV-2 scBCR-seq scRNA-seq scTCR-seq Sequencing severe acute respiratory syndrome Coronavirus shown signature significant increase single-cell status T cell T cells T-cell receptor TCR Temra cells virus Virus neutralization
[DOI] 10.3389/fimmu.2021.733539 PMC 바로가기 [Article Type] Immunology

Assessment of Macrophage Inflammatory Biomarkers and Neutrophil Extracellular Traps Associated Proteins in COVID-19 Patients

Conference abstract

Published on 2021-11-232022-10-05
Journal: Blood [Category] 바이오마커,

[키워드] activate Activation acute respiratory distress Adaptive immune response age Analysis assessment Biobank Biomarker Blood cause cfDNA Characteristics chitinase circulating clinical clinical manifestations clinical variable Comorbidities contribute control group COVID-19 COVID-19 patient COVID19 critically ill patients cytokine Cytokine storm D-dimer database decrease demographic disease severity DNA download dysregulated immune response Elastase endothelial damage ethics committee European evaluate explained ferritin figure Follow-up GDPR group healthy control Hospitalization hospitalized patient Hypothesis increase in induce Infection Inflammation inflammation marker knowledge Macrophage macrophage activation Mann-Whitney U test marker microthrombi MPO multiple organ failure NET NETosis neutrophil Neutrophil extracellular trap Patient protection provided Research Result resulting routine clinical practice SARS-CoV-2 infected subjects SARS-COV-2 infection selected Septic shock severe complication severe COVID-19 disease shown statistical statistically significant stratified supported symptom onset syndrome System the median the patient thrombosis thrombotic complication Vascular damage were measured were used
[DOI] 10.1182/blood-2021-148166 [Article Type] Conference abstract

Longitudinal analysis of FcRL5 expression and clonal relationships among classical and atypical memory B cells following malaria

말라리아 이후 고전적 및 비정형 기억 B 세포 간의 FcRL5 발현 및 클론 관계에 대한 종단적 분석

Research

Published on 2021-11-102024-08-08
Journal: Malaria Journal [Category] 말라리아,

[키워드] Adaptive immune response B cell differentiation B cell receptor BCR-sequencing Humoral immunity Infection Plasmodium falciparum
[DOI] 10.1186/s12936-021-03970-1 PMC 바로가기 [Article Type] Research